- 3-Bromo-4-fluoronitrobenzene
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- $8.00 / 1KG
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2025-09-25
- CAS:701-45-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 3-Bromo-4-fluoronitrobenzene Basic information |
| | 3-Bromo-4-fluoronitrobenzene Chemical Properties |
| Melting point | 55°C | | Boiling point | 250.6±20.0 °C(Predicted) | | density | 1.808±0.06 g/cm3(Predicted) | | Fp | 105° | | storage temp. | Sealed in dry,Room Temperature | | form | Solid | | color | White or Colorless to Light yellow to Light orange | | Water Solubility | Slightly soluble in water. | | InChI | 1S/C6H3BrFNO2/c7-5-3-4(9(10)11)1-2-6(5)8/h1-3H | | InChIKey | FAWMTDSAMOCUAR-UHFFFAOYSA-N | | SMILES | [O-][N+](=O)c1ccc(F)c(Br)c1 | | CAS DataBase Reference | 701-45-1(CAS DataBase Reference) |
| Hazard Codes | Xi,Xn | | WGK Germany | WGK 3 | | HazardClass | IRRITANT | | HS Code | 29049090 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Acute Tox. 4 Oral |
| | 3-Bromo-4-fluoronitrobenzene Usage And Synthesis |
| Chemical Properties | Light yellow solid | | Uses | Reatant in the synthesis of N-fused tricyclic indoles, dimethyamine, benzofuran. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 63, p. 8448, 1998 DOI: 10.1021/jo981557o | | Synthesis | Example 4: 3.0 g (0.054 mol) of iron powder was added to 250 g (1.77 mol) of 4-fluoronitrobenzene and the mixture was heated to 140 °C. Over a period of 9 hours, 450 g (2.81 mol) of bromine was slowly added dropwise and supplemented with 15 g (0.27 mol) of iron powder in batches. After the dropwise addition was completed, stirring of the reaction mixture was continued for 6 hours. After completion of the reaction, the mixture was filtered and the filtrate was dissolved in 530 g of hot hexane. After cooling the solution, 220 g of 3-bromo-4-fluoronitrobenzene crystals precipitated in a yield of 55.8% of the theoretical value, with the product having a melting point of 55.5°C-56.5°C and a purity of 99.0%. | | References | [1] Patent: US4446075, 1984, A |
| | 3-Bromo-4-fluoronitrobenzene Preparation Products And Raw materials |
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