| Company Name: |
T&W GROUP |
| Tel: |
021-61551611 13296011611 |
| Email: |
contact@trustwe.com |
Br-PEG5-acid manufacturers
- Br-PEG5-acid
-
-
2025-06-07
- CAS:1817735-27-5
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
|
| | Br-PEG5-acid Basic information |
| Product Name: | Br-PEG5-acid | | Synonyms: | Br-PEG5-acid;Bromo-PEG5-propionic acid;Br-PEG5-CH2CH2COOH;Bromo-PEG5-C2-acid;Br-PEG5-CH2CH2COOH/Propanoic acid, 3-[(14-bromo-3,6,9,12-tetraoxatetradec-1-yl)oxy]-;Propanoic acid, 3-[(14-bromo-3,6,9,12-tetraoxatetradec-1-yl)oxy]-;1-Bromo-3,6,9,12,15-pentaoxaoctadecan-18-oic acid | | CAS: | 1817735-27-5 | | MF: | C13H25BrO7 | | MW: | 373.24 | | EINECS: | | | Product Categories: | | | Mol File: | 1817735-27-5.mol |  |
| | Br-PEG5-acid Chemical Properties |
| Boiling point | 462.1±45.0 °C(Predicted) | | density | 1.320±0.06 g/cm3(Predicted) | | pka | 4.28±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | Br-PEG5-acid Usage And Synthesis |
| Description | Bromo-PEG5-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | | Uses | Bromo-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Br-PEG5-acid Preparation Products And Raw materials |
|