Mal-PEG5-COOtBu manufacturers
- Mal-PEG5-Boc
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- $30.00
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2026-05-11
- CAS:2250216-91-0
- Purity: 99.72%
- Supply Ability: 10g
- Mal-PEG5-COOtBu
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2025-06-07
- CAS:2250216-91-0
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | Mal-PEG5-COOtBu Basic information |
| Product Name: | Mal-PEG5-COOtBu | | Synonyms: | Mal-PEG5-COOtBu;Mal-PEG5-CH2CH2COOtBu;Mal-PEG5-Boc;Inhibitor,Mal-PEG-5-Boc,inhibit,MalPEG5Boc,PROTAC Linkers,Mal PEG5 Boc;Mal-PEG5-CH2CH2COOtBu/4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester;4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester;tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oate | | CAS: | 2250216-91-0 | | MF: | C21H35NO9 | | MW: | 445.5 | | EINECS: | | | Product Categories: | | | Mol File: | 2250216-91-0.mol |  |
| | Mal-PEG5-COOtBu Chemical Properties |
| Boiling point | 533.2±50.0 °C(Predicted) | | density | 1.152±0.06 g/cm3(Predicted) | | solubility | Soluble in DCM | | pka | -2.34±0.20(Predicted) |
| | Mal-PEG5-COOtBu Usage And Synthesis |
| Description | Mal-PEG5-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | | Uses | Mal-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Mal-PEG5-COOtBu Preparation Products And Raw materials |
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