METHYL 4-BROMO-3-METHOXYBENZOATE synthesis
- Product Name:METHYL 4-BROMO-3-METHOXYBENZOATE
- CAS Number:17100-63-9
- Molecular formula:C9H9BrO3
- Molecular Weight:245.07
106291-80-9
177 suppliers
$8.00/250mg
77-78-1
321 suppliers
$22.00/25g
17100-63-9
129 suppliers
$9.00/250mg
Yield:17100-63-9 99%
Reaction Conditions:
with potassium carbonate in acetone; for 3 h;Heating / reflux;
Steps:
35.B
Step B. Methyl 4-bromo-3-methoxybenzoate A solution of methyl 4-bromo-3-hydroxybenzoate of Step A (27 mmol), potassium carbonate (33 mmol), and dimethyl sulfate (32 mmol) in acetone (40 mL) was stirred at reflux temperature under nitrogen atmosphere for three hours. The mixture was cooled and 5 mL of water was added. The acetone was evaporated and 30 mL of water was added. The product was extracted into dichloromethane. The organic solution was dried over anhydrous magnesium sulfate, filtered and evaporated to give the title compound (6.5 g, 99%) as a hard, white crystalline solid.
References:
US2006/199806,2006,A1 Location in patent:Page/Page column 23
106291-80-9
177 suppliers
$8.00/250mg
74-88-4
352 suppliers
$15.00/10g
17100-63-9
129 suppliers
$9.00/250mg
14348-38-0
163 suppliers
$14.00/1g
74-88-4
352 suppliers
$15.00/10g
17100-63-9
129 suppliers
$9.00/250mg
67-56-1
776 suppliers
$9.00/25ml
56256-14-5
149 suppliers
$26.00/1g
17100-63-9
129 suppliers
$9.00/250mg
3556-83-0
165 suppliers
$7.00/1g
17100-63-9
129 suppliers
$9.00/250mg