Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
logo
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook

Welcome back!

Structured search
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List pyridine-3-sulfonyl chloride
16133-25-8

pyridine-3-sulfonyl chloride synthesis

8synthesis methods
Add thionyl chloride to the water, cool to about 0-5°C, and add cuprous chloride. Fluoboric acid diazonium salt was added to the solution and reacted at 0-5°C overnight. The reaction solution was extracted with dichloromethane, combining the organic layers. The organic layer was washed once with saturated aqueous sodium bicarbonate solution, once with water, and finally once with saturated brine. The product was dried over anhydrous sodium sulfate and filtered, and the filtrate was concentrated to remove methylene chloride to obtain the product pyridine-3-sulfonyl chloride with a yield of 90.7%.
pyridine-3-sulfonyl chloride
636-73-7 Synthesis
3-Pyridinesulfonic acid

636-73-7
408 suppliers
$5.00/5g

pyridine-3-sulfonyl chloride

16133-25-8
473 suppliers
$6.00/1g

-

Yield:16133-25-8 94%

Reaction Conditions:

with phosphorus pentachloride;trichlorophosphate for 3 h;Heating / reflux;

Steps:

B.1.1

A mixture of pyridine-3-sulfonic acid (10.3 g, 64.8 mmol), phosphorus pentachloride (20.82 g, 100 mmol) and phosphorus oxychloride (10 mL, 109 mmol) was heated to reflux for 3 h (according to J. Org. Chem. 1989, 54(2), 389.). Evaporated to dryness to give a yellow solid, dissolved in ice water and methyl-tert-butyl ether, added cautiously sat. NaHCO3-sol. until neutralized, saturated with solid NaCl, separated phases, dried organic layer over Na2SO4. Removal of the solvent in vacuum to give the title compound as an orange liquid (10.85 g, 94%). MS (ISP) 178.1 [(M+H)+] and 180.0 [(M+2+H)+].

References:

US2006/217387,2006,A1 Location in patent:Page/Page column 25

462-08-8 Synthesis
3-Aminopyridine

462-08-8
484 suppliers
$14.00/25g

pyridine-3-sulfonyl chloride

16133-25-8
473 suppliers
$6.00/1g

References
42899-76-3 Synthesis
Pyridine-3-sulfonyl chloride hydrochloride

42899-76-3
172 suppliers
$13.43/1gm:

pyridine-3-sulfonyl chloride

16133-25-8
473 suppliers
$6.00/1g

References
626-55-1 Synthesis
3-Pyridyl bromide

626-55-1
576 suppliers
$5.00/5/ G

pyridine-3-sulfonyl chloride

16133-25-8
473 suppliers
$6.00/1g

References
Pyridine-3-thiol

16133-26-9
22 suppliers
inquiry

pyridine-3-sulfonyl chloride

16133-25-8
473 suppliers
$6.00/1g

References

pyridine-3-sulfonyl chloride Related Search:

5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde N-NITROSO-DI-ISO-PROPYLAMINE Malononitrile 3 5-DICHLOROPYRIDINE 1-OXIDE 98 3-Pyridinesulfonic acid 3-Chloropyridine 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde 2'-Fluoroacetophenone 4-Pyridinesulphonic acid 3-(2-(pyridin-3-yl)disulfanyl)pyridine