| Identification | Back Directory | [Name]
E3 ligase Ligand-Linker Conjugates 17 | [CAS]
1950635-16-1 | [Synonyms]
E3 ligase Ligand-Linker Conjugates 17
Cereblon Ligand -Linker Conjugates 2 TFA
Pomalidomide Related Compound 6 Triflate
E3 Ligase Ligand-Linker Conjugates 20 (TFA)
N-(8-Aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate | [Molecular Formula]
C25H31F3N4O8 | [MDL Number]
MFCD31560485 | [MOL File]
1950635-16-1.mol | [Molecular Weight]
572.54 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [form ]
Solid | [color ]
White to off-white | [InChIKey]
AJVLNIUPDHKOPS-UHFFFAOYSA-N | [SMILES]
O=C(C(F)(F)F)[O-].O=C(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)NCCCCCCCC[NH3+] |
| Hazard Information | Back Directory | [Uses]
Thalidomide-O-amido-C8-NH2 TFA (Cereblon Ligand -Linker Conjugates 2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. | [IC 50]
Cereblon | [References]
[1] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2. |
|
| Company Name: |
Henan Alfachem Co.,Ltd.
|
| Tel: |
0371-55051623 18137891487 |
| Website: |
www.chemicalbook.com/supplier/14555231/ |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|