1950635-16-1

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1950635-16-1 Structure

Identification	Back Directory
[Name] E3 ligase Ligand-Linker Conjugates 17
[CAS] 1950635-16-1
[Synonyms] E3 ligase Ligand-Linker Conjugates 17 Cereblon Ligand -Linker Conjugates 2 TFA Pomalidomide Related Compound 6 Triflate E3 Ligase Ligand-Linker Conjugates 20 (TFA) N-(8-Aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate
[Molecular Formula] C25H31F3N4O8
[MDL Number] MFCD31560485
[MOL File] 1950635-16-1.mol
[Molecular Weight] 572.54

Safety Data	Back Directory
[Symbol(GHS) ] GHS07,GHS02
[Signal word ] Warning
[Hazard statements ] H315-H319-H226
[Precautionary statements ] P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235

Hazard Information	Back Directory
[Uses] Thalidomide-O-amido-C8-NH2 TFA (Cereblon Ligand -Linker Conjugates 2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
[IC 50] Cereblon
[References] [1] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.

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