ChemicalBook--->CAS DataBase List--->1950635-14-9

1950635-14-9

1950635-14-9 Structure

1950635-14-9 Structure
IdentificationBack Directory
[Name]

E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate
[CAS]

1950635-14-9
[Synonyms]

Thalidomide-O-amido-C6-NH2 TFA
E3 ligase Ligand-Linker Conjugates 25
Cereblon Ligand-Linker Conjugates 11 TFA
E3 Ligase Ligand-Linker Conjugates 25 TFA
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate
[Molecular Formula]

C23H27F3N4O8
[MDL Number]

MFCD31715439
[MOL File]

1950635-14-9.mol
[Molecular Weight]

544.48
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C, stored under nitrogen
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].
[IC 50]

Cereblon
[References]

[1] Bradner J, et al. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses. WO 2017024318 A1
Spectrum DetailBack Directory
[Spectrum Detail]

E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate(1950635-14-9)1HNMR
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