| Identification | Back Directory | [Name]
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate | [CAS]
1950635-14-9 | [Synonyms]
Thalidomide-O-amido-C6-NH2 TFA E3 ligase Ligand-Linker Conjugates 25 Cereblon Ligand-Linker Conjugates 11 TFA E3 Ligase Ligand-Linker Conjugates 25 TFA E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate | [Molecular Formula]
C23H27F3N4O8 | [MDL Number]
MFCD31715439 | [MOL File]
1950635-14-9.mol | [Molecular Weight]
544.48 |
| Hazard Information | Back Directory | [Uses]
Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1]. | [IC 50]
Cereblon | [References]
[1] Bradner J, et al. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses. WO 2017024318 A1 |
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