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1957236-21-3

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1957236-21-3 Structure

1957236-21-3 Structure
IdentificationBack Directory
[Name]

E3 ligase Ligand-Linker Conjugates 14
[CAS]

1957236-21-3
[Synonyms]

E3 ligase Ligand-Linker Conjugates 14
Pomalidomide Related Compound 5 Triflate
Cereblon Ligand-Linker Conjugates 3 (TFA)
E3 ligase Ligand-Linker Conjugates 14 (TFA)
[Molecular Formula]

C25H31F3N4O11
[MDL Number]

MFCD31560482
[MOL File]

1957236-21-3.mol
[Molecular Weight]

620.529
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
[IC 50]

Cereblon
[References]

[1] BRADNER, James, et al. METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES. WO2017024317A2.
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