| Identification | More | [Name]
1-Bromo-2-nitrobenzene | [CAS]
577-19-5 | [Synonyms]
1-BROMO-2-NITROBENZENE
2-BROMONITROBENZENE
2-Nitrobromobenzene
AURORA KA-1883
O-BROMONITROBENZENE
O-NITROBROMOBENZENE
1-bromo-2-nitro-benzen
Benzene,1-bromo-2-nitro-
o-Nitrophenyl bromide
o-nitrophenylbromide
1-BROMO-2-NITROBENZENE, 99+%
0-Bromonitrobenzene
BENZENE,ORTHO-BROMONITRO-
ORTHO-BROMONITROBENZENE
2-Bromo-1-nitrobenzene
2-Nitrophenyl bromide | [EINECS(EC#)]
209-409-0 | [Molecular Formula]
C6H4BrNO2 | [MDL Number]
MFCD00007045 | [Molecular Weight]
202.01 | [MOL File]
577-19-5.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
40-42 °C (lit.) | [Boiling point ]
261 °C (lit.) | [density ]
1.7 g/cm3 (20℃) | [refractive index ]
1.6060 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
powder to crystal | [color ]
Light yellow to Amber to Dark green | [Stability:]
Stable. Combustible. Incompatible with strong bases, strong oxidizing agents. | [Water Solubility ]
insoluble | [BRN ]
2044109 | [InChI]
1S/C6H4BrNO2/c7-5-3-1-2-4-6(5)8(9)10/h1-4H | [InChIKey]
ORPVVAKYSXQCJI-UHFFFAOYSA-N | [SMILES]
[O-][N+](=O)c1ccccc1Br | [CAS DataBase Reference]
577-19-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzene, 1-bromo-2-nitro-(577-19-5) | [EPA Substance Registry System]
577-19-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S22:Do not breathe dust . | [RIDADR ]
UN 3459 6.1/PG 3
| [WGK Germany ]
3
| [RTECS ]
CY9040450
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29049085 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
1-Bromo-2-nitrobenzene may be used in the preparation of:
- 4-methoxy-2′-nitrodiphenyl ether
- 1-methoxy-3,5-bis-(2-nitro-phenoxy)benzene
- 5-hydroxy-3-methoxy-2′-nitrodiphenyl ether
| [Uses]
1-Bromo-2-nitrobenzene is used in organic synthesis. It also can react with 2-methylamino-benzoic acid to get N-methyl-N-(2-nitro-phenyl)-anthranilic acid. And it is also used in the preparation of 4-methoxy-2?-nitrodiphenyl ether, 1-methoxy-3,5-bis-(2-nitro-phenoxy)benzene. | [General Description]
1-Bromo-2-nitrobenzene undergoes palladium[0]-mediated Ullmann cross-coupling reaction with a range of β-halo-enals, -enones or -esters to afford the corresponding β-aryl derivatives. Palladium[0]-mediated Ullmann cross-coupling reaction of 1-bromo-2-nitrobenzene with β-bromo-α,β-unsaturated aldehydes is reported. | [Purification Methods]
Crystallise it twice from pet ether, using charcoal before the first crystallisation. [Beilstein 5 III 618, 5 IV 728.] |
|
|