3-Formyl-4-hydroxybenzoic acid
- CAS No.
- 584-87-2
- Chemical Name:
- 3-Formyl-4-hydroxybenzoic acid
- Synonyms
- 3-FormyL;-4-hydroxybenzoic acid;3-Formyl-4-hydroxybenzoic acid;3-formyl-4-hydroxybenzonic acid;4-HYDROXYISOPHTHALALDEHYDIC ACID;Benzoic acid, 3-formyl-4-hydroxy-;3-ForMyl-4-hydroxybenzoic acid 97%;4-hydroxy-3-methanoyl-benzoic acid;4-HYDROXYISOPHTHALALDEHYDIC ACID 97%;3-FORMYL-4-HYDROXYBENZOIC ACID HEMIHYDRATE
- CBNumber:
- CB0232122
- Molecular Formula:
- C8H6O4
- Molecular Weight:
- 166.13
- MDL Number:
- MFCD00016595
- MOL File:
- 584-87-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 246-250 °C (lit.) |
|---|---|
| Boiling point | 254.32°C (rough estimate) |
| Density | 1.3579 (rough estimate) |
| refractive index | 1.5090 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 4.22±0.10(Predicted) |
| Appearance | White to yellow Solid |
| InChI | InChI=1S/C8H6O4/c9-4-6-3-5(8(11)12)1-2-7(6)10/h1-4,10H,(H,11,12) |
| InChIKey | NXZBZWZORYEIJL-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C(O)C(C=O)=C1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H317-H319 |
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338 |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22-36/38 |
| Safety Statements | 26-36/37 |
| WGK Germany | 2 |
| HS Code | 2918999090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 |
3-Formyl-4-hydroxybenzoic acid price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 633488 | 3-Formyl-4-hydroxybenzoic acid 97% | 584-87-2 | 1g | $252 | 2026-04-30 | Buy |
| Sigma-Aldrich | 633488 | 3-Formyl-4-hydroxybenzoic acid 97% | 584-87-2 | 5g | $447.75 | 2026-04-30 | Buy |
| Biosynth | FF34543 | 3-Formyl-4-hydroxybenzoic acid | 584-87-2 | 10g | $150 | 2026-06-04 | Buy |
| Biosynth | FF34543 | 3-Formyl-4-hydroxybenzoic acid | 584-87-2 | 5g | $150 | 2026-06-04 | Buy |
| Biosynth | FF34543 | 3-Formyl-4-hydroxybenzoic acid | 584-87-2 | 25g | $188.25 | 2026-06-04 | Buy |
3-Formyl-4-hydroxybenzoic acid Chemical Properties, Uses, Production
Uses
3-FORMYL-4-HYDROXYBENZOIC ACID is used as an intermediate in the synthesis of MOF material ligands or COF material monomers.
Synthesis
100-97-0
99-96-7
584-87-2
GENERAL METHOD: To a solution of trifluoroacetic acid (5 mL) of the substrate (1a-1q, 0.15 mmol) was sequentially added hexamethylenetetramine (urotropine, 0.3 mmol) and cuprous oxide (0.15 mmol). The reaction mixture was heated to reflux for 5 h and subsequently cooled to room temperature. A 3 N hydrochloric acid solution (5 mL) was slowly added to the reaction system and stirring was continued for 1 hour. Upon completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography (200-300 mesh) to afford the target product 3-formyl-4-hydroxybenzoic acid.
References
[1] Bioconjugate Chemistry, 2018, vol. 29, # 9, p. 2909 - 2919
[2] Dalton Transactions, 2010, vol. 39, # 8, p. 2070 - 2077
[3] European Journal of Inorganic Chemistry, 2012, # 32, p. 5225 - 5238
[4] Research on Chemical Intermediates, 2015, vol. 41, # 11, p. 8147 - 8158
[5] Chemical Communications, 2018, vol. 54, # 42, p. 5385 - 5388
3-Formyl-4-hydroxybenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TR Pharma & Tech Co., Ltd. | 0531-88633905 15863156350 | jntryy@hotmail.com | China | 45 | 55 |
| Shanghai Zhen Li Biological Technology Co., Ltd | 021-16621358918; 18516310516;16621358918;13045646768 | zhenlipharma888@163.com | China | 19060 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Aemon Chemical | 0086-755-86198205 | acinfo@aemonchem.com | China | 1928 | 57 |
| Beijing Taiya Jie Technology Development Co., Ltd. | 021-33690831-8001 13552411790;18616022633 | postmaster@tyjchem.cn | China | 1541 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 |
View Latest Price from 3-Formyl-4-hydroxybenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-16 | 3-FORMYL-4-HYDROXYBENZOIC ACID
584-87-2
|
1KG | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2020-01-01 | 3-FORMYL-4-HYDROXYBENZOIC ACID
584-87-2
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 3-FORMYL-4-HYDROXYBENZOIC ACID
584-87-2
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 3-FORMYL-4-HYDROXYBENZOIC ACID
584-87-2
- $1.00
- 99%
- Career Henan Chemical Co
