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2-Amino-6-chloro-3-nitropyridine

2-Amino-6-chloro-3-nitropyridine Structure
2-Amino-6-chloro-3-nitropyridine structure
CAS No.
27048-04-0
Chemical Name:
2-Amino-6-chloro-3-nitropyridine
Synonyms
6-CHLORO-3-NITROPYRIDIN-2-AMINE;LABOTEST-BB LT00012599;2-Amino-6-chloro-3-nitrop...;2-amino-3-nitrochloropyridine;6-Chlor-3-nitropyridin-2-amin;2-Amino-3-nitro-6-chloropyridi;2-Amino-6-chloro-nitro pyridne;2-Amino-6-chlor-3-nitropyridin;FlupirtinemaleateintermediateI;6-Chloro-3-nitro-2-pyridinamine
CBNumber:
CB0245762
Molecular Formula:
C5H4ClN3O2
Molecular Weight:
173.56
MDL Number:
MFCD00044350
MOL File:
27048-04-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 17:24:13
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2-Amino-6-chloro-3-nitropyridine Properties

Melting point 195-196
Boiling point 339.9±37.0 °C(Predicted)
Density 1.596±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Chloroform, DMSO
form Crystalline
pka -1.69±0.50(Predicted)
color Yellow
Water Solubility Slightly soluble in water. Soluble in dimethyl sulfoxide and chloroform.
InChI InChI=1S/C5H4ClN3O2/c6-4-2-1-3(9(10)11)5(7)8-4/h1-2H,(H2,7,8)
InChIKey WERABQRUGJIMKQ-UHFFFAOYSA-N
SMILES C1(N)=NC(Cl)=CC=C1[N+]([O-])=O
CAS DataBase Reference 27048-04-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Warning
Hazard statements  H302-H312-H315-H319-H331-H335
Precautionary statements  P261-P280-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-26-36/37/39
RIDADR  2811
Hazard Note  Irritant
HazardClass  6.1
PackingGroup  Ⅲ
HS Code  29333999
REACH Registrations Active
NFPA 704
0
2 0

2-Amino-6-chloro-3-nitropyridine price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A1756 2-Amino-6-chloro-3-nitropyridine 27048-04-0 5G $32 2026-04-30 Buy
TCI Chemical A1756 2-Amino-6-chloro-3-nitropyridine 27048-04-0 25G $95 2026-04-30 Buy
TRC TRC-A603495-25G 6-Amino-2-chloro-5-nitropyridine 27048-04-0 25g $1133 2026-06-03 Buy
TRC TRC-A603495-2.5G 6-Amino-2-chloro-5-nitropyridine 27048-04-0 2.5g $154 2026-06-03 Buy
AstaTech 20246 2-AMINO-3-NITRO-6-CHLOROPYRIDINE 97% 27048-04-0 25G $13 2026-04-30 Buy
Product number Packaging Price Buy
A1756 5G $32 Buy
A1756 25G $95 Buy
TRC-A603495-25G 25g $1133 Buy
TRC-A603495-2.5G 2.5g $154 Buy
20246 25G $13 Buy

2-Amino-6-chloro-3-nitropyridine Chemical Properties, Uses, Production

Description

2-Amino-6-chloro-3-nitropyridine is a cytotoxic drug that has been shown to have anti-viral potency, as well as antiviral activity in an activity test. It is synthesized by reacting hydrogen tartrate with oxadiazole, and then hydrolyzing the resulting product with chloride. 2-Amino-6-chloro-3-nitropyridine has also been shown to inhibit human immunodeficiency virus type 1 (HIV) replication in vitro and to be effective against other viruses such as type 2 influenza. This drug can bind to the viral envelope and inhibit fusion of the viral membrane with host cells by preventing the release of viral contents into the cytoplasm. The binding affinity of 2-amino 6-chloro 3 nitropyridine for chloride may be due to hydrogen bonding interactions.

Chemical Properties

YELLOW POWDER

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Synthesis

The 2-Amino-6-chloro-3-nitropyridine may be obtained by the ammonolysis of 2,6-dichloro-3-nitropyridine by a known process. The ammonolysis is carried out by using solution of aqueous ammonia in methanol at 35°–40° C. After the reaction is over, the product is obtained by filtration.

References

[1] Patent: CN103936766, 2016, B. Location in patent: Paragraph 0034-0035
[2] Patent: US2015/152057, 2015, A1. Location in patent: Paragraph 0111; 0112; 0113
[3] Patent: WO2009/27732, 2009, A1. Location in patent: Page/Page column 69-70
[4] Patent: WO2004/2986, 2004, A2. Location in patent: Page 127-128
[5] Collection of Czechoslovak Chemical Communications, 1991, vol. 56, # 11.1, p. 2420 - 2429

2-Amino-6-chloro-3-nitropyridine synthesis

16013-85-7
27048-04-0
Synthesis of 2-Amino-6-chloro-3-nitropyridine from 2,6-Dichloro-3-nitropyridine

2-Amino-6-chloro-3-nitropyridine Preparation Products And Raw materials

Raw materials

2(1H)-Pyridinone, 6-amino-5-nitro- Ethanol 2-Chloro-6-methoxy-3-nitropyridine Ammonia 2,6-Dichloro-3-nitropyridine
2-Amino-6-methoxy-3-nitropyridine 2,6-Dichloropyridine

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Preparation Products

Flupirtine 6-Chloro-2,3-diaminopyridine 2,3-Diamino-6-chloropyridine N-(6-Chloro-3-nitropyridin-2-yl)acetamide tert-Butyl carbazate
2-Amino-5-nitropyridine 2-Chloro-5-nitropyridin-4-amine 2-Chloro-5-nitropyridine 6-Bromopyridine-2,3-diamine 2-AMino-6-(benzylaMino)-3-nitropyridine
(5-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)methanol 5-broMo-6-ethoxy-3-nitropyridin-2-aMine

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2-Amino-6-chloro-3-nitropyridine Suppliers

Global Suppliers ( 413)
Supplier Tel Email Country ProdList Advantage
Weifang Siyuan Chemical Co., Ltd. 0536-8888106 17663601818 2354379876@qq.com China 244 58
Shandong Mingfeng Pharmaceutical and Technology Co. Ltd 053155551677 15315114555 1345456643@qq.com China 298 58
Nanbu County Chengxin Technology Co., Ltd. 0838-5675166 15883665058 nbcxkj@126.com China 956 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Jinxiang Chemical (Danyang) Products Co., Ltd. 025-86819862 13913839793 nancyzong@jinchemical.com China 97 74
Supplier Advantage
Weifang Siyuan Chemical Co., Ltd. 58
Shandong Mingfeng Pharmaceutical and Technology Co. Ltd 58
Nanbu County Chengxin Technology Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
INTATRADE GmbH 66
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56
Energy Chemical 61
Jinxiang Chemical (Danyang) Products Co., Ltd. 74

View Latest Price from 2-Amino-6-chloro-3-nitropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-6-chloro-3-nitropyridine pictures 2026-09-11 2-Amino-6-chloro-3-nitropyridine
27048-04-0
 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
2-Amino-6-chloro-3-nitropyridine pictures 2026-08-20 2-Amino-6-chloro-3-nitropyridine
27048-04-0
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Amino-6-chloro-3-nitropyridine pictures 2026-06-30 2-Amino-6-chloro-3-nitropyridine
27048-04-0
 25KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd

2-Amino-6-chloro-3-nitropyridine Spectrum

2-Amino-6-chloro-3-nitropyridine(27048-04-0)1HNMR2-Amino-6-chloro-3-nitropyridine(27048-04-0)FT-IR

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2-AMINO-6-CHLORO-3-NITROPYRIDINE 2-AMINO-3-NITRO-6-CHLOROPYRIDINE 6-chloro-3-nitropyridin-2-ylamine 2-amino-3-nitrochloropyridine 2-AMINO-6-CHLOR-3-NITROPYRIDIN 95% 2-Amino-3-nitro-6-chloropyridi 2-Amino-6-chloro-3-nitropyridine 98% LABOTEST-BB LT00012599 2-Amino-6-chloro-nitro pyridne 6-Amino-2-chloro-5-nitropyridine 6-Chloro-3-nitro-2-pyridinamine 2-Amino-3-nitro-6-chloropyridine ,98% 6-Chloro-3-nitropyridine-2-amine 2-Amino-6-chloro-3-nitropyridine,97% 6-Chloro-3-nitro-2-pyridylamine 2-Amino-6-chloro-3-nitrop... 2-Amino-6-chlor-3-nitropyridin 2-Pyridinamine, 6-chloro, 3-nitro- 2-AMINO-6-CHLORO-3-NITROYRIDINE 2-AMine-3-nitro-6-chloropyridine 2-AMINO-6-CHOLORO-3-NITRO PYRIDINE ( RE- EXPORT SHIPMENT ) FlupirtinemaleateintermediateI 6-Chlor-3-nitropyridin-2-amin 2-Amino-6-chloro-3-nitropyridine ISO 9001：2015 REACH 2-amino-3-nitro-6-chloropyridineQ: What is 2-amino-3-nitro-6-chloropyridine Q: What is the CAS Number of 2-amino-3-nitro-6-chloropyridine Q: What is the storage condition of 2-amino-3-nitro-6-chloropyridine Q: What are the applications of 2-amino-3-nitro-6-chloropyridine 6-Chloro-3-nitro pyridine-2-ylamine 6-Chlor-3-nitropyridin-2-ylamin Product: 2-Amino-6-chloro-3-nitropyridine 2-AMINO-6-CHLOR-3-NITROPYRIDIN 95% 6-CHLORO-3-NITROPYRIDIN-2-AMINE 27048-04-0 C5H4CIN2O2 Aromatics Heterocycles Miscellaneous Reagents Pyridines Pyridine pyridine derivative Amines blocks NitroCompounds