2-Fluoropyridine-6-carboxylic acid
- CAS No.
- 402-69-7
- Chemical Name:
- 2-Fluoropyridine-6-carboxylic acid
- Synonyms
- 6-FLUOROPICOLINIC ACID;65753;2-Fluoroyridine-6;uoro-2-pyridinecarboxyL;5-Amino-6-chloro-4-picoline;2-Fluoroyridine-6-carboxylicacid;2-Fluoropyridine-6-carboxylicaci;6-Fluoro-2-pyridinecarboxylicacid;2-FLUOROPYRIDINE-6-CARBOXYLIC ACID;2-FLUORO-6-PYRIDINECARBOXYLIC ACID
- CBNumber:
- CB0426291
- Molecular Formula:
- C6H4FNO2
- Molecular Weight:
- 141.1
- MDL Number:
- MFCD02181193
- MOL File:
- 402-69-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-Fluoro-2-pyridinecarboxylic acid 97% | 593664 | 250mg | $118 |
| 6-Fluoro-2-pyridinecarboxylic Acid >98.0%(T) | F0837 | 1g | $53 |
| 6-Fluoro-2-pyridinecarboxylic Acid >98.0%(T) | F0837 | 5g | $181 |
| 6-Fluoropyridine-2-carboxylic acid 98% | PC3966 | 1g | $21 |
| 6-Fluoropyridine-2-carboxylic acid 98% | PC3966 | 5g | $30 |
| More product size | |||
| Melting point | 139-143 °C (lit.) |
|---|---|
| Boiling point | 306.3±22.0 °C(Predicted) |
| Density | 1.419±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 3.30±0.10(Predicted) |
| form | Powder or Crystalline Powder |
| color | White to yellow to pale brown |
| InChI | 1S/C6H4FNO2/c7-5-3-1-2-4(8-5)6(9)10/h1-3H,(H,9,10) |
| InChIKey | DIEMCUFYSOEIDU-UHFFFAOYSA-N |
| SMILES | OC(=O)c1cccc(F)n1 |
| CAS DataBase Reference | 402-69-7(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Fluoropyridine-6-carboxylic acid price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 593664 | 6-Fluoro-2-pyridinecarboxylic acid 97% | 402-69-7 | 250mg | $118 | 2023-06-20 | Buy |
| TCI Chemical | F0837 | 6-Fluoro-2-pyridinecarboxylic Acid >98.0%(T) | 402-69-7 | 1g | $53 | 2026-04-30 | Buy |
| TCI Chemical | F0837 | 6-Fluoro-2-pyridinecarboxylic Acid >98.0%(T) | 402-69-7 | 5g | $181 | 2026-04-30 | Buy |
| Apolloscientific | PC3966 | 6-Fluoropyridine-2-carboxylic acid 98% | 402-69-7 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC3966 | 6-Fluoropyridine-2-carboxylic acid 98% | 402-69-7 | 5g | $30 | 2026-06-04 | Buy |
2-Fluoropyridine-6-carboxylic acid Chemical Properties,Uses,Production
Chemical Properties
White to light yellow powder
Uses
2-Fluoropyridine-6-carboxylic acid serves as a ligand in the synthesis of Cu(II) metal complexes [5].
Synthesis
407-22-7
402-69-7
General procedure for the synthesis of 6-fluoro-2-pyridinecarboxylic acid from 2-fluoro-6-methylpyridine: to a solution of 2-fluoro-6-methylpyridine (2.5 g, 22.5 mmol) in water (170 ml) was added potassium permanganate (KMnO, 2 g, 12.65 mmol) in batches and the mixture was heated to reflux. Subsequently, potassium permanganate (KMnO, 8 g, 50.63 mmol) was added in batches and heating to reflux was continued for 3 hours. After completion of the reaction, the mixture was cooled and the precipitate was removed by filtration. The filtrate was acidified with hydrochloric acid (HCl) solution and subsequently concentrated under reduced pressure. The residue was ground with hot ethanol (EtOH), the solid was collected by filtration and the filtrate was concentrated to dryness under reduced pressure. 6-Fluoro-2-pyridinecarboxylic acid was finally obtained as a white solid (1.7 g, 53% yield); melting point 137 °C.
References
[1] Patent: WO2004/13135, 2004, A1. Location in patent: Page 46-47
[2] Patent: WO2004/13138, 2004, A2. Location in patent: Page 22
[3] Journal of Fluorine Chemistry, 2011, vol. 132, # 8, p. 541 - 547
[4] Journal of the American Chemical Society, 1949, vol. 71, p. 4152
[5]
Tamer, Ö., Şimşek, M., Avcı, D., Başoğlu, A., Bensebaa, M., Boukelkoul, M., Dege, N., Atalay, Y. (2025). Exploring the structural, vibrational, thermal, and nonlinear optical properties of a novel Cu(II) complex of 6-fluoro-pyridine-2-carboxylic acid. Journal of Molecular Structure, 1342, 142707. https://doi.org/10.1016/j.molstruc.2025.142707
2-Fluoropyridine-6-carboxylic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20111 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8827 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17339 | 58 |
| Hefei Hangang Pharmaceutical Technology Co., Ltd. | +8618062405514 | ada@ipurechemical.com | China | 10224 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; 19817745290 | bd@blocksynth.com | China | 5971 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9983 | 58 |
View Lastest Price from 2-Fluoropyridine-6-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 2-Fluoropyridine-6-carboxylic acid
402-69-7
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | 2-Fluoropyridine-6-carboxylic acid
402-69-7
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-06-25 | 2-Fluoropyridine-6-carboxylic acid
402-69-7
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd |
-
- 2-Fluoropyridine-6-carboxylic acid
402-69-7
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 2-Fluoropyridine-6-carboxylic acid
402-69-7
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-Fluoropyridine-6-carboxylic acid
402-69-7
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
