2-Fluoro-3-nitropyridine
- CAS No.
- 1480-87-1
- Chemical Name:
- 2-Fluoro-3-nitropyridine
- Synonyms
- uoro-3-nitropyridine;2-Fluoro-3-nitropyri;2-FLUORO-3-NITROPYRIDINE;2-Fluoro-3-nitrylpyridine;2-Fluoro-3-nitropyridine>Pyridine, 2-fluoro-3-nitro-;2-Fluoro-3-nitropyridine,98%;2-Fluoro-3-nitropyridine, 97+%;3-bromo-2-fluoro-5-trifluoromethyl ryridine;2-Fluoro-3-nitropyridine ISO 9001：2015 REACH
- CBNumber:
- CB0427546
- Molecular Formula:
- C5H3FN2O2
- Molecular Weight:
- 142.09
- MDL Number:
- MFCD03095068
- MOL File:
- 1480-87-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 18℃ |
|---|---|
| Boiling point | 110℃/10mm |
| Density | 1.439±0.06 g/cm3(Predicted) |
| refractive index | 1.5300 to 1.5340 |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Low Melting Solid |
| pka | -4.47±0.10(Predicted) |
| color | Yellow |
| Water Solubility | Slightly soluble in water. |
| CAS DataBase Reference | 1480-87-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | T,Xi,C | |||||||||
| Risk Statements | 20/21/22-36/37/38-34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| Hazard Note | Toxic | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2-Fluoro-3-nitropyridine price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0982 | 2-Fluoro-3-nitropyridine >98.0%(GC) | 1480-87-1 | 5g | $43 | 2026-04-30 | Buy |
| TCI Chemical | F0982 | 2-Fluoro-3-nitropyridine >98.0%(GC) | 1480-87-1 | 25g | $144 | 2026-04-30 | Buy |
| Apolloscientific | PC9190 | 2-Fluoro-3-nitropyridine 95% | 1480-87-1 | 10g | $63 | 2026-06-04 | Buy |
| Apolloscientific | PC9190 | 2-Fluoro-3-nitropyridine 95% | 1480-87-1 | 25g | $89 | 2026-06-04 | Buy |
| Apolloscientific | PC9190 | 2-Fluoro-3-nitropyridine 95% | 1480-87-1 | 100g | $335 | 2026-06-04 | Buy |
2-Fluoro-3-nitropyridine Chemical Properties, Uses, Production
Uses
2-Fluoro-3-nitropyridine is used as a pharmaceutical intermediate.
Synthesis
5470-18-8
1480-87-1
General procedure for the synthesis of 2-fluoro-3-nitropyridine from 2-chloro-3-nitropyridine: 2-chloro-3-nitropyridine (1.00 g, 6.76 mmol) was dissolved in DMSO (33.8 ml) at room temperature, followed by addition of CsF (2.053 g, 13.51 mmol). The reaction mixture was stirred in air at 110°C for 20 hrs. After completion of the reaction, the reaction mixture was quenched with ice water and extracted with EtOAc. The organic layer was separated, washed sequentially with water and brine, dried over anhydrous Na2SO4 and concentrated under reduced pressure. Purification of the residue by column chromatography (silica gel as stationary phase and EtOAc/hexane as eluent) afforded 2-fluoro-3-nitropyridine (0.639 g, 4.86 mmol, 71.9% yield) as a colorless oil. Similarly, compounds 3B'-8B' can be prepared according to the synthesis of 2B' above.
References
[1] European Journal of Inorganic Chemistry, 2017, vol. 2017, # 2, p. 330 - 339
[2] Tetrahedron Letters, 2015, vol. 56, # 44, p. 6043 - 6046
[3] Heterocycles, 1986, vol. 24, # 11, p. 3213 - 3221
[4] Journal of Labelled Compounds and Radiopharmaceuticals, 2004, vol. 47, # 6, p. 373 - 383
[5] Tetrahedron, 2001, vol. 57, # 4, p. 739 - 750
2-Fluoro-3-nitropyridine Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
View Latest Price from 2-Fluoro-3-nitropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 2-Fluoro-3-nitropyridine
1480-87-1
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-20 | 2-Fluoro-3-nitropyridine
1480-87-1
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2026-06-30 | 2-Fluoro-3-nitropyridine
1480-87-1
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 2-Fluoro-3-nitropyridine
1480-87-1
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 2-Fluoro-3-nitropyridine
1480-87-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2-Fluoro-3-nitropyridine
1480-87-1
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
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