2-Fluoro-3-nitropyridine
- CAS No.
- 1480-87-1
- Chemical Name:
- 2-Fluoro-3-nitropyridine
- Synonyms
- uoro-3-nitropyridine;2-Fluoro-3-nitropyri;2-FLUORO-3-NITROPYRIDINE;2-Fluoro-3-nitrylpyridine;2-Fluoro-3-nitropyridine>Pyridine, 2-fluoro-3-nitro-;2-Fluoro-3-nitropyridine,98%;2-Fluoro-3-nitropyridine, 97+%;3-bromo-2-fluoro-5-trifluoromethyl ryridine;2-Fluoro-3-nitropyridine ISO 9001：2015 REACH
- CBNumber:
- CB0427546
- Molecular Formula:
- C5H3FN2O2
- Molecular Weight:
- 142.09
- MDL Number:
- MFCD03095068
- MOL File:
- 1480-87-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Fluoro-3-nitropyridine >98.0%(GC) | F0982 | 5g | $43 |
| 2-Fluoro-3-nitropyridine >98.0%(GC) | F0982 | 25g | $144 |
| 2-Fluoro-3-nitropyridine 95% | PC9190 | 10g | $63 |
| 2-Fluoro-3-nitropyridine 95% | PC9190 | 25g | $89 |
| 2-Fluoro-3-nitropyridine 95% | PC9190 | 100g | $335 |
| More product size | |||
| Melting point | 18℃ |
|---|---|
| Boiling point | 110℃/10mm |
| Density | 1.439±0.06 g/cm3(Predicted) |
| refractive index | 1.5300 to 1.5340 |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Low Melting Solid |
| pka | -4.47±0.10(Predicted) |
| color | Yellow |
| Water Solubility | Slightly soluble in water. |
| CAS DataBase Reference | 1480-87-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | T,Xi,C | |||||||||
| Risk Statements | 20/21/22-36/37/38-34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| Hazard Note | Toxic | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2-Fluoro-3-nitropyridine price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0982 | 2-Fluoro-3-nitropyridine >98.0%(GC) | 1480-87-1 | 5g | $43 | 2026-04-30 | Buy |
| TCI Chemical | F0982 | 2-Fluoro-3-nitropyridine >98.0%(GC) | 1480-87-1 | 25g | $144 | 2026-04-30 | Buy |
| Apolloscientific | PC9190 | 2-Fluoro-3-nitropyridine 95% | 1480-87-1 | 10g | $63 | 2026-06-04 | Buy |
| Apolloscientific | PC9190 | 2-Fluoro-3-nitropyridine 95% | 1480-87-1 | 25g | $89 | 2026-06-04 | Buy |
| Apolloscientific | PC9190 | 2-Fluoro-3-nitropyridine 95% | 1480-87-1 | 100g | $335 | 2026-06-04 | Buy |
2-Fluoro-3-nitropyridine Chemical Properties,Uses,Production
Uses
2-Fluoro-3-nitropyridine is used as a pharmaceutical intermediate.
Synthesis
5470-18-8
1480-87-1
General procedure for the synthesis of 2-fluoro-3-nitropyridine from 2-chloro-3-nitropyridine: 2-chloro-3-nitropyridine (1.00 g, 6.76 mmol) was dissolved in DMSO (33.8 ml) at room temperature, followed by addition of CsF (2.053 g, 13.51 mmol). The reaction mixture was stirred in air at 110°C for 20 hrs. After completion of the reaction, the reaction mixture was quenched with ice water and extracted with EtOAc. The organic layer was separated, washed sequentially with water and brine, dried over anhydrous Na2SO4 and concentrated under reduced pressure. Purification of the residue by column chromatography (silica gel as stationary phase and EtOAc/hexane as eluent) afforded 2-fluoro-3-nitropyridine (0.639 g, 4.86 mmol, 71.9% yield) as a colorless oil. Similarly, compounds 3B'-8B' can be prepared according to the synthesis of 2B' above.
References
[1] European Journal of Inorganic Chemistry, 2017, vol. 2017, # 2, p. 330 - 339
[2] Tetrahedron Letters, 2015, vol. 56, # 44, p. 6043 - 6046
[3] Heterocycles, 1986, vol. 24, # 11, p. 3213 - 3221
[4] Journal of Labelled Compounds and Radiopharmaceuticals, 2004, vol. 47, # 6, p. 373 - 383
[5] Tetrahedron, 2001, vol. 57, # 4, p. 739 - 750
2-Fluoro-3-nitropyridine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20120 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Changzhou Carman Chemical Co., Ltd. | 15061933924 | CHINA | 514 | 58 | |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 2-Fluoro-3-nitropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-09 | 2-Fluoro-3-nitropyridine
1480-87-1
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | 2-Fluoro-3-nitropyridine
1480-87-1
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-02-02 | 2-Fluoro-3-nitropyridine
1480-87-1
|
$1.00 | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 2-Fluoro-3-nitropyridine
1480-87-1
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 2-Fluoro-3-nitropyridine
1480-87-1
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-Fluoro-3-nitropyridine
1480-87-1
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
