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2-Fluoro-6-trifluoromethylpyridine

CAS No.
94239-04-0
Chemical Name:
2-Fluoro-6-trifluoromethylpyridine
Synonyms
2-FLUORO-6-(TRIFLUOROMETHYL)PYRIDINE;2-Fluoro-6-(trifluoromethyl)py;2-FLUORO-6-RIFLUOROMETHYLPYRIDINE;2-Trifluoromethyl-6-fluoropyridine;2-Fluooro-6-trifluoroMethylpyridine;-Fluoro-6-(trifluoromethyl)pyridine;2-Fluoro-6-(trifluoromethyl)pyridine>Pyridine, 2-fluoro-6-(trifluoroMethyl)-;2-Fluoro-6-(trifluoromethyl)pyridine,98%;2-Fluoro-6-(trifluoromethyl)pyridine 98%
CBNumber:
CB0466314
Molecular Formula:
C6H3F4N
Molecular Weight:
165.09
MDL Number:
MFCD03092901
MOL File:
94239-04-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 22:42:44

2-Fluoro-6-trifluoromethylpyridine Properties

Boiling point 121.6±35.0 °C(Predicted)
Density 1.371±0.06 g/cm3(Predicted)
vapor pressure 5.6hPa at 25℃
refractive index 1.4010-1.4050
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -5.11±0.12(Predicted)
form clear liquid
color Colorless to Almost colorless
Water Solubility 1.9g/L at 25℃
InChI InChI=1S/C6H3F4N/c7-5-3-1-2-4(11-5)6(8,9)10/h1-3H
InChIKey IZOIOCQPMHHDHN-UHFFFAOYSA-N
SMILES C1(F)=NC(C(F)(F)F)=CC=C1
LogP 1.83 at 25℃
CAS DataBase Reference 94239-04-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H302+H332-H412-H302-H332-H402
Precautionary statements  P210-P233-P240-P241+P242+P243-P261-P264-P270-P271-P273-P280-P301+P312+P330-P303+P361+P353-P304+P340+P312-P403+P235-P501-P280a-P304+P340-P501a
Hazard Codes  Xi,T
Risk Statements  20/21/22-36/37/38-36-25
Safety Statements  26-36/37/39-45
RIDADR  1993
Hazard Note  Irritant
HazardClass  3
PackingGroup  III
HS Code  2933399960
REACH Registrations Active
NFPA 704
2
2 0

2-Fluoro-6-trifluoromethylpyridine price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical F0826 2-Fluoro-6-(trifluoromethyl)pyridine >98.0%(GC) 94239-04-0 5g $28 2026-04-30 Buy
TCI Chemical F0826 2-Fluoro-6-(trifluoromethyl)pyridine >98.0%(GC) 94239-04-0 25g $84 2026-04-30 Buy
Usbiological 276719 2-Fluoro-6-trifluoromethylpyridine Asreported 94239-04-0 5g $429 2026-06-03 Buy
Usbiological 276719 2-Fluoro-6-trifluoromethylpyridine Asreported 94239-04-0 10g $656 2026-06-03 Buy
Usbiological 276719 2-Fluoro-6-trifluoromethylpyridine Asreported 94239-04-0 25g $938 2026-06-03 Buy
Product number Packaging Price Buy
F0826 5g $28 Buy
F0826 25g $84 Buy
276719 5g $429 Buy
276719 10g $656 Buy
276719 25g $938 Buy

2-Fluoro-6-trifluoromethylpyridine Chemical Properties, Uses, Production

Synthesis

At 0°C, 2-chloro-6-trichloromethylpyridine, hydrofluoric acid, ferric chloride, and solvent were slowly added to a vacuum-dried pressure-resistant tube. The resulting mixture was stirred at 170°C for 4 hours, and the reaction progress was monitored by gas chromatography. The reaction was cooled to room temperature, and after the reaction was complete, a saturated sodium carbonate aqueous solution was slowly added to the reaction system to neutralize the acid produced during the reaction, adjusting the pH of the reaction system to alkaline. After extraction with ethyl acetate, the organic layer was dried, and then evaporated to dryness to obtain the target product.

Synthesis of 94239-04-0

Figure: Synthetic route of 2-fluoro-6-trifluoromethylpyridine

Chemical Properties

Cloroless to light yellow liquid

Uses

2-Fluoro-6-trifluoromethylpyridine is a useful research chemical used in the preparation of 2-(3-alkoxy-1H-pyrazol-1-yl)azines as inhibitors of human dihydroorotate dehydrogenase.

2-Fluoro-6-trifluoromethylpyridine Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 305)
Supplier Tel Email Country ProdList Advantage
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. 13396369453 18678026865 sdfantai@163.com China 904 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60

View Latest Price from 2-Fluoro-6-trifluoromethylpyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Fluoro-6-trifluoromethylpyridine pictures 2026-08-20 2-Fluoro-6-trifluoromethylpyridine
94239-04-0
$1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Fluoro-6-trifluoromethylpyridine pictures 2026-03-20 2-Fluoro-6-trifluoromethylpyridine
94239-04-0
$10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Fluoro-6-trifluoromethylpyridine pictures 2026-02-28 2-Fluoro-6-trifluoromethylpyridine
94239-04-0
250kg Purity: 99% 1000tons Shandong Jihui Chemical Co., Ltd.

2-Fluoro-6-trifluoromethylpyridine Spectrum

2-FLUORO-6-(TRIFLUOROMETHYL)PYRIDINE 2-FLUORO-6-RIFLUOROMETHYLPYRIDINE 2-Trifluoromethyl-6-fluoropyridine 2-Fluoro-6-(trifluoromethyl)pyridine 98% 2-Fluoro-6-(trifluoromethyl)py 2-Fluooro-6-trifluoroMethylpyridine Pyridine, 2-fluoro-6-(trifluoroMethyl)- 2-Fluoro-6-(trifluoromethyl)pyridine,98% -Fluoro-6-(trifluoromethyl)pyridine 2-Fluoro-6-(trifluoromethyl)pyridine> 2-Fluoro-6-trifluoromethylpyridine ISO 9001:2015 REACH 94239-04-0 92239-04-0 1826-34-0 Pyridine Pyridines derivates API intermediates Halides blocks FluoroCompounds Pyridines Pyridines, Pyrimidines, Purines and Pteredines