2-Fluoro-6-trifluoromethylpyridine
- CAS No.
- 94239-04-0
- Chemical Name:
- 2-Fluoro-6-trifluoromethylpyridine
- Synonyms
- 2-FLUORO-6-(TRIFLUOROMETHYL)PYRIDINE;2-Fluoro-6-(trifluoromethyl)py;2-FLUORO-6-RIFLUOROMETHYLPYRIDINE;2-Trifluoromethyl-6-fluoropyridine;2-Fluooro-6-trifluoroMethylpyridine;-Fluoro-6-(trifluoromethyl)pyridine;2-Fluoro-6-(trifluoromethyl)pyridine>Pyridine, 2-fluoro-6-(trifluoroMethyl)-;2-Fluoro-6-(trifluoromethyl)pyridine,98%;2-Fluoro-6-(trifluoromethyl)pyridine 98%
- CBNumber:
- CB0466314
- Molecular Formula:
- C6H3F4N
- Molecular Weight:
- 165.09
- MDL Number:
- MFCD03092901
- MOL File:
- 94239-04-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 121.6±35.0 °C(Predicted) |
|---|---|
| Density | 1.371±0.06 g/cm3(Predicted) |
| vapor pressure | 5.6hPa at 25℃ |
| refractive index | 1.4010-1.4050 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | -5.11±0.12(Predicted) |
| form | clear liquid |
| color | Colorless to Almost colorless |
| Water Solubility | 1.9g/L at 25℃ |
| InChI | InChI=1S/C6H3F4N/c7-5-3-1-2-4(11-5)6(8,9)10/h1-3H |
| InChIKey | IZOIOCQPMHHDHN-UHFFFAOYSA-N |
| SMILES | C1(F)=NC(C(F)(F)F)=CC=C1 |
| LogP | 1.83 at 25℃ |
| CAS DataBase Reference | 94239-04-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H302+H332-H412-H302-H332-H402 | |||||||||
| Precautionary statements | P210-P233-P240-P241+P242+P243-P261-P264-P270-P271-P273-P280-P301+P312+P330-P303+P361+P353-P304+P340+P312-P403+P235-P501-P280a-P304+P340-P501a | |||||||||
| Hazard Codes | Xi,T | |||||||||
| Risk Statements | 20/21/22-36/37/38-36-25 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | 1993 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2933399960 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
2-Fluoro-6-trifluoromethylpyridine price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0826 | 2-Fluoro-6-(trifluoromethyl)pyridine >98.0%(GC) | 94239-04-0 | 5g | $28 | 2026-04-30 | Buy |
| TCI Chemical | F0826 | 2-Fluoro-6-(trifluoromethyl)pyridine >98.0%(GC) | 94239-04-0 | 25g | $84 | 2026-04-30 | Buy |
| Usbiological | 276719 | 2-Fluoro-6-trifluoromethylpyridine Asreported | 94239-04-0 | 5g | $429 | 2026-06-03 | Buy |
| Usbiological | 276719 | 2-Fluoro-6-trifluoromethylpyridine Asreported | 94239-04-0 | 10g | $656 | 2026-06-03 | Buy |
| Usbiological | 276719 | 2-Fluoro-6-trifluoromethylpyridine Asreported | 94239-04-0 | 25g | $938 | 2026-06-03 | Buy |
2-Fluoro-6-trifluoromethylpyridine Chemical Properties, Uses, Production
Synthesis
At 0°C, 2-chloro-6-trichloromethylpyridine, hydrofluoric acid, ferric chloride, and solvent were slowly added to a vacuum-dried pressure-resistant tube. The resulting mixture was stirred at 170°C for 4 hours, and the reaction progress was monitored by gas chromatography. The reaction was cooled to room temperature, and after the reaction was complete, a saturated sodium carbonate aqueous solution was slowly added to the reaction system to neutralize the acid produced during the reaction, adjusting the pH of the reaction system to alkaline. After extraction with ethyl acetate, the organic layer was dried, and then evaporated to dryness to obtain the target product.

Figure: Synthetic route of 2-fluoro-6-trifluoromethylpyridine
Chemical Properties
Cloroless to light yellow liquid
Uses
2-Fluoro-6-trifluoromethylpyridine is a useful research chemical used in the preparation of 2-(3-alkoxy-1H-pyrazol-1-yl)azines as inhibitors of human dihydroorotate dehydrogenase.
2-Fluoro-6-trifluoromethylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. | 13396369453 18678026865 | sdfantai@163.com | China | 904 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
View Latest Price from 2-Fluoro-6-trifluoromethylpyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-20 | 2-Fluoro-6-trifluoromethylpyridine
94239-04-0
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
![]() |
2026-03-20 | 2-Fluoro-6-trifluoromethylpyridine
94239-04-0
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
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2026-02-28 | 2-Fluoro-6-trifluoromethylpyridine
94239-04-0
|
250kg | Purity: 99% | 1000tons | Shandong Jihui Chemical Co., Ltd. |
-

- 2-Fluoro-6-trifluoromethylpyridine
94239-04-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-

- 2-Fluoro-6-trifluoromethylpyridine
94239-04-0
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 2-Fluoro-6-trifluoromethylpyridine
94239-04-0
- Purity: 99%
- Shandong Jihui Chemical Co., Ltd.
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