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3-Trifluoromethylpyridine

3-Trifluoromethylpyridine Structure
3-Trifluoromethylpyridine structure
CAS No.
3796-23-4
Chemical Name:
3-Trifluoromethylpyridine
Synonyms
3-(TRIFLUOROMETHYL)PYRIDINE;3-TP;3-TF;AKOS BBS-00001545;à,à,à-trifluoro-3-picoline;3- trifloro methyl pyridine;Pyridine, 3-(trifluoromethyl)-;3-(Trifluoromethyl)pyridine97%;3-(Trifluoromethyl)pyridine 97%;alpha,alpha,alpha-Trifluoro-3-picoline
CBNumber:
CB0480671
Molecular Formula:
C6H4F3N
Molecular Weight:
147.1
MDL Number:
MFCD00100032
MOL File:
3796-23-4.mol
MSDS File:
SDS
Last updated:2026-05-27 22:44:56
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3-Trifluoromethylpyridine Properties

Boiling point 113-115 °C (lit.)
Density 1.276 g/mL at 25 °C
refractive index n20/D 1.418
Flash point 74 °F
storage temp. Inert atmosphere,Room Temperature
form clear liquid
pka 2.80±0.10(Predicted)
color Colorless to Light yellow
BRN 1563102
InChI InChI=1S/C6H4F3N/c7-6(8,9)5-2-1-3-10-4-5/h1-4H
InChIKey JTZSFNHHVULOGJ-UHFFFAOYSA-N
SMILES C1=NC=CC=C1C(F)(F)F
CAS DataBase Reference 3796-23-4(CAS DataBase Reference)
FDA UNII 625H9FC8CE
NIST Chemistry Reference 3-(CF3)-pyridine(3796-23-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Skull and Crossbones (GHS06)
GHS02,GHS06
Signal word  Danger
Hazard statements  H226-H300-H315-H319-H335
Precautionary statements  P210-P233-P240-P301+P310-P303+P361+P353-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  T,Xi,F
Risk Statements  10-25-36/37/38-11
Safety Statements  26-45-37-36
RIDADR  UN 1992 3/PG 3
WGK Germany  2
Hazard Note  Irritant
HazardClass  3
PackingGroup  II
HS Code  2933399990
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 2 Oral
Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
3
2 0

3-Trifluoromethylpyridine price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 643564 3-(Trifluoromethyl)pyridine 97% 3796-23-4 1g $136 2022-05-15 Buy
TCI Chemical T2786 3-(Trifluoromethyl)pyridine >98.0%(GC) 3796-23-4 5g $66 2026-04-30 Buy
TCI Chemical T2786 3-(Trifluoromethyl)pyridine >98.0%(GC) 3796-23-4 25g $205 2026-04-30 Buy
Apolloscientific PC7766G 3-(Trifluoromethyl)pyridine 97% 3796-23-4 1g $21 2026-06-04 Buy
Apolloscientific PC7766G 3-(Trifluoromethyl)pyridine 97% 3796-23-4 5g $33 2026-06-04 Buy
Product number Packaging Price Buy
643564 1g $136 Buy
T2786 5g $66 Buy
T2786 25g $205 Buy
PC7766G 1g $21 Buy
PC7766G 5g $33 Buy

3-Trifluoromethylpyridine Chemical Properties,Uses,Production

Synthesis

Use copper iodide (I) (13.3 mg, 0.07 mmol), 1,10-phenanthroline (12.6 mg, 0.07 mmol), KF (61 mg, 1.05 mmol, 3 eq.), and aryl iodide (0.35 mmol, 1 eq.). Close the reaction vessel, then evacuate and refill three times with argon or nitrogen. Add DMSO (1.0 mL) and aryl iodide (0.35 mmol) (if it is not solid), B(OMe)3 (109 mg, 117 μL, 1.05 mmol, 3 eq.), and TMSCF3 (149.3 mg, 155 μL, 1.05 mmol, 3 eq.) via syringe.

(eq.). The solid aryl iodide was weighed directly in the reaction vessel. The resulting orange-yellow suspension was stirred at 60°C for 24 hours. The sample was dissolved in Et₂O and analyzed by GC-MS to obtain 3-trifluoromethylpyridine, yield: 100%.

Chemical Properties

Colorless liquid;Pale yellow liqui

Uses

3-(Trifluoromethyl)pyridine is a reagent used to improve amyloid detection in the brain during MRI.

3-Trifluoromethylpyridine synthesis

65753-47-1
3796-23-4
Synthesis of 3-Trifluoromethylpyridine from 2-Chloro-3-(trifluoromethyl)pyridine

3-Trifluoromethylpyridine Preparation Products And Raw materials

Raw materials

2-Chloro-3-(trifluoromethyl)pyridine 2,5-Dichloro-3-(trifluoromethyl)pyridine 2,5,6-Trichloro-3-trifluoromethylpyridine Copper, (trifluoromethyl)- 3-Iodopyridine

Preparation Products

5-isothiocyanato-3-(trifluoromethyl)picolinonitrile 4-(Trifluoromethyl)pyridine 3-(Trifluoromethyl)pyridine-2-carboxylic acid

3-Trifluoromethylpyridine Suppliers

Global( 277)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing XiLang Chemical Products Co., Ltd. 18936048580 chemxilang@163.com China 3909 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Changzhou Huanling Chemical Co., Ltd. 89803005 18206112582 info@huanlingchem.com China 983 68
Supplier Advantage
Nanjing XiLang Chemical Products Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
INTATRADE GmbH 66
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Capot Chemical Co., Ltd 66
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Changzhou Huanling Chemical Co., Ltd. 68

View Lastest Price from 3-Trifluoromethylpyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Trifluoromethylpyridine pictures 2026-09-02 3-Trifluoromethylpyridine
3796-23-4
 $5.00 1KG 98% Henan Fengda Chemical Co., Ltd
3-Trifluoromethylpyridine pictures 2026-08-20 3-Trifluoromethylpyridine
3796-23-4
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
3-Trifluoromethylpyridine pictures 2026-06-30 3-Trifluoromethylpyridine
3796-23-4
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd

3-Trifluoromethylpyridine Spectrum

3-Trifluoromethylpyridine(3796-23-4)1HNMR

3796-23-4(3-Trifluoromethylpyridine)Related Search:

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2-Chloro-3-(trifluoromethyl)pyridine Pyridine 3-Chloro-5-(trifluoromethyl)pyridine 2,3-Dichloro-5-(trichloromethyl)pyridine 2,6-Dichloro-3-(trifluoromethyl)pyridine
2-Chloro-5-trifluoromethylpyridine 2,5,6-Trichloro-3-trifluoromethylpyridine 2-Amino-3-chloro-5-(trifluoromethyl)pyridine

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AKOS BBS-00001545 Pyridine, 3-(trifluoromethyl)- à,à,à-trifluoro-3-picoline 3-(Trifluoromethyl)pyridine 97% 3-(Trifluoromethyl)pyridine97% alpha,alpha,alpha-Trifluoro-3-picoline 3-Trifluoromethylpyridine ISO 9001：2015 REACH 3-TF TIANFUCHEM--3796-23-4--3-Trifluoromethylpyridine 3-TP 3- trifloro methyl pyridine 3-(Trifluoromethyl)pyridine CAS：3796-23-4 3-(TRIFLUOROMETHYL)PYRIDINE 3796-23-4 3976-23-4 135497-98-3 C6H4F3N Pyridines Heterocyclic Building Blocks Building Blocks C6 Heterocyclic Building Blocks Pyridines Pyridine Heterocyclic Compounds C6