Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Chloro-4,5-diaminopyrimidine

2-Chloro-4,5-diaminopyrimidine

2-Chloro-4,5-diaminopyrimidine Structure
2-Chloro-4,5-diaminopyrimidine structure
CAS No.
14631-08-4
Chemical Name:
2-Chloro-4,5-diaminopyrimidine
Synonyms
2-CHLOROPYRIMIDINE-4,5-DIAMINE;IFLAB-BB F1371-0155;6-Chloro-2,3-PyriMidinediaMine;2-CHLORO-4,5-DIAMONOPYRIMIDINE;4,5-DIAMINO-2-CHLOROPYRIMIDINE;2-CHLORO-4,5-DIAMINOPYRIMIDINE;4,5-Pyrimidinediamine, 2-chloro-;(4-amino-2-chloro-pyrimidin-5-yl)amin;4,5-Pyrimidinediamine, 2-chloro- (9CI);(4-amino-2-chloro-pyrimidin-5-yl)amine
CBNumber:
CB0754718
Molecular Formula:
C4H5ClN4
Molecular Weight:
144.56
MDL Number:
MFCD00047355
MOL File:
14631-08-4.mol
MSDS File:
SDS
Last updated:2026-05-27 22:51:19
Product description Number Pack Size Price
2-Chloropyrimidine-4,5-diamine 119065 1.00g $324
2-Chloropyrimidine-4,5-diamine 119065 5.00g $972
2-Chloropyrimidine-4,5-diamine 119065 10.00g $1548
2-Chloropyrimidine-4,5-diamine 90+% C9428 100mg $20
2-Chloropyrimidine-4,5-diamine 90+% C9428 250mg $28
More product size
Request For Quotation

2-Chloro-4,5-diaminopyrimidine Properties

Melting point 220 °C (decomp)
Boiling point 417.9±25.0 °C(Predicted)
Density 1.564±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 3.61±0.10(Predicted)
Appearance Off-white to light brown Solid
InChI InChI=1S/C4H5ClN4/c5-4-8-1-2(6)3(7)9-4/h1H,6H2,(H2,7,8,9)
InChIKey QDUJVEOOSNUDDW-UHFFFAOYSA-N
SMILES C1(Cl)=NC=C(N)C(N)=N1
CAS DataBase Reference 14631-08-4(CAS DataBase Reference)
FDA UNII TW5LFP3QGS

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36-43
Safety Statements  26-36/37
HS Code  2933599590

2-Chloro-4,5-diaminopyrimidine price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 119065 2-Chloropyrimidine-4,5-diamine 14631-08-4 1.00g $324 2026-05-18 Buy
Matrix Scientific 119065 2-Chloropyrimidine-4,5-diamine 14631-08-4 5.00g $972 2026-05-18 Buy
Matrix Scientific 119065 2-Chloropyrimidine-4,5-diamine 14631-08-4 10.00g $1548 2026-05-18 Buy
Synthonix C9428 2-Chloropyrimidine-4,5-diamine 90+% 14631-08-4 100mg $20 2026-05-06 Buy
Synthonix C9428 2-Chloropyrimidine-4,5-diamine 90+% 14631-08-4 250mg $28 2026-05-06 Buy
Product number Packaging Price Buy
119065 1.00g $324 Buy
119065 5.00g $972 Buy
119065 10.00g $1548 Buy
C9428 100mg $20 Buy
C9428 250mg $28 Buy

2-Chloro-4,5-diaminopyrimidine Chemical Properties,Uses,Production

Synthesis

A mixture of 2-chloro-5-nitropyrimidin-4-amine (1.0 g, 5.7 mmol) and SnCl2·2H2O (5.2 g, 22.9 mmol) in EtOH (55 mL) under N2 was heated to 80 °C and stirred for two hours. The mixture was then concentrated under reduced pressure. EtOAc and Celite were added to the residue, and the mixture was basified with saturated Na2CO3 (aq.) to pH 9- 10. The mixture was filtered through a pad of Celite and washed with EtOAc. The organic layer was separated, washed with brine, dried (Na2SO4), and concentrated in a vacuum. The residue was purified on ISCO (20 g silica gel column, EtOAc/hexanes 0~100 per cent) to give 2-Chloro-4,5-diaminopyrimidine (0.41 g 49 per cent).

References

[1] Patent: US2017/313683, 2017, A1. Location in patent: Paragraph 0544
[2] Patent: WO2016/171755, 2016, A1. Location in patent: Paragraph 0176
[3] Journal of Organic Chemistry, 1955, vol. 20, p. 829,833,835
[4] Nature (London, United Kingdom), 1948, vol. 162, p. 524
[5] Journal of the Chemical Society, 1951, p. 474,478

2-Chloro-4,5-diaminopyrimidine synthesis

1920-66-7
14631-08-4
Synthesis of 2-Chloro-4,5-diaminopyrimidine from 2-CHLORO-5-NITROPYRIMIDIN-4-AMINE

2-Chloro-4,5-diaminopyrimidine Preparation Products And Raw materials

Raw materials

5-Nitrouracil Ammonium hydroxide Nickel Phosphorus oxitrichloride N,N-Diethylaniline
2-CHLORO-5-NITROPYRIMIDIN-4-AMINE Ethanol Ammonium chloride Water Iron

1of2

Preparation Products

2-Chloropurine

2-Chloro-4,5-diaminopyrimidine Suppliers

Global( 138)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29640 60
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10403 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
KARMEL TECHNOLOGY (HK) CO.,LIMITED 		+8618795957998 karmelhk@126.com CHINA 2886 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 18895 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Shenzhen Nexconn Pharmatechs Ltd 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
SIMAGCHEM CORP 		58
KARMEL TECHNOLOGY (HK) CO.,LIMITED 		58
Dideu Industries Group Limited 		58

View Lastest Price from 2-Chloro-4,5-diaminopyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLORO-4,5-DIAMINOPYRIMIDINE pictures 2025-11-18 2-CHLORO-4,5-DIAMINOPYRIMIDINE
14631-08-4
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-CHLORO-4,5-DIAMINOPYRIMIDINE pictures 2021-08-12 2-CHLORO-4,5-DIAMINOPYRIMIDINE
14631-08-4
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2-Chloro-4,5-diamino pyrimidine pictures 2021-07-13 2-Chloro-4,5-diamino pyrimidine
14631-08-4
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

2-Chloro-4,5-diaminopyrimidine Spectrum

2-Chloro-4,5-diaminopyrimidine(14631-08-4)MS2-Chloro-4,5-diaminopyrimidine(14631-08-4)1HNMR2-Chloro-4,5-diaminopyrimidine(14631-08-4)IR12-Chloro-4,5-diaminopyrimidine(14631-08-4)IR2

14631-08-4(2-Chloro-4,5-diaminopyrimidine)Related Search:

2-CHLORO-4,5-DIAMINOPYRIMIDINE 2-CHLORO-5-NITROPYRIMIDIN-4-AMINE 2-Chloro-6-methylpyrimidine-4,5-diamine 6-Chloro-4,5-diaminopyrimidine,4-CHLORO-5,6-DIAMINOPYRIMIDINE 4-Chloro-2,6-diaminopyrimidine
4,5-Diaminopyrimidine 2,6-Diamino-4-chloropyrimidine 1-oxide 4-AMINO-2-CHLORO-6-METHYL-5-NITROPYRIMIDINE 2-chloro-N4-methylpyrimidine-4,5-diamine 4-AMINO-2-CHLORO-5-NITRO-6-(METHYLAMINO)PYRIMIDINE
2-chloro-N4-propylpyrimidine-4,5-diamine 4-(6-Amino-2-chloro-5-nitro-4-pyrimidinyl)morpholine 2-CHLORO-5-NITRO-4-METHYL-6-(METHYLAMINO)PYRIMIDINE N4,6-DIMETHYL-N4-PHENYL-2-CHLORO-5-NITROPYRIMIDIN-4-AMINE 4-AMINO-2-CHLORO-5-NITRO-6-PIPERIDIN-1-YLPYRIMIDINE
2-CHLORO-4-(2,2-DIPHENYLHYDRAZINO)-5-NITROPYRIMIDINE 2-CHLORO-6-PHENYL-4,5-PYRIMIDINEDIAMINE CHEMBRDG-BB 5145935

1of4

IFLAB-BB F1371-0155 2-CHLORO-4,5-DIAMINOPYRIMIDINE 4,5-DIAMINO-2-CHLOROPYRIMIDINE (4-amino-2-chloro-pyrimidin-5-yl)amine 4,5-Pyrimidinediamine, 2-chloro- (9CI) 2-CHLORO-4,5-DIAMONOPYRIMIDINE 6-Chloro-2,3-PyriMidinediaMine (4-amino-2-chloro-pyrimidin-5-yl)amin 4,5-Pyrimidinediamine, 2-chloro- 2-CHLORO-4,5-DIAMINOPYRIMIDINE ISO 9001：2015 REACH 2-CHLOROPYRIMIDINE-4,5-DIAMINE 14631-08-4 Heterocycle-Pyrimidine series PYRIMIDINE APIs & Intermediate pharmacetical Building Blocks