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2-Chloro-4,5-diaminopyrimidine

2-Chloro-4,5-diaminopyrimidine Structure
2-Chloro-4,5-diaminopyrimidine structure
CAS No.
14631-08-4
Chemical Name:
2-Chloro-4,5-diaminopyrimidine
Synonyms
2-CHLOROPYRIMIDINE-4,5-DIAMINE;IFLAB-BB F1371-0155;6-Chloro-2,3-PyriMidinediaMine;2-CHLORO-4,5-DIAMONOPYRIMIDINE;4,5-DIAMINO-2-CHLOROPYRIMIDINE;2-CHLORO-4,5-DIAMINOPYRIMIDINE;4,5-Pyrimidinediamine, 2-chloro-;(4-amino-2-chloro-pyrimidin-5-yl)amin;4,5-Pyrimidinediamine, 2-chloro- (9CI);(4-amino-2-chloro-pyrimidin-5-yl)amine
CBNumber:
CB0754718
Molecular Formula:
C4H5ClN4
Molecular Weight:
144.56
MDL Number:
MFCD00047355
MOL File:
14631-08-4.mol
MSDS File:
SDS
Last updated:2026-05-27 22:51:19
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2-Chloro-4,5-diaminopyrimidine Properties

Melting point 220 °C (decomp)
Boiling point 417.9±25.0 °C(Predicted)
Density 1.564±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 3.61±0.10(Predicted)
Appearance Off-white to light brown Solid
InChI InChI=1S/C4H5ClN4/c5-4-8-1-2(6)3(7)9-4/h1H,6H2,(H2,7,8,9)
InChIKey QDUJVEOOSNUDDW-UHFFFAOYSA-N
SMILES C1(Cl)=NC=C(N)C(N)=N1
CAS DataBase Reference 14631-08-4(CAS DataBase Reference)
FDA UNII TW5LFP3QGS

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36-43
Safety Statements  26-36/37
HS Code  2933599590

2-Chloro-4,5-diaminopyrimidine price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 267644 2-Chloro-4,5-diaminopyrimidine Asreported 14631-08-4 250mg $396 2026-06-03 Buy
Usbiological 267644 2-Chloro-4,5-diaminopyrimidine Asreported 14631-08-4 500mg $581 2026-06-03 Buy
Usbiological 267644 2-Chloro-4,5-diaminopyrimidine Asreported 14631-08-4 1g $835 2026-06-03 Buy
Usbiological 267644 2-Chloro-4,5-diaminopyrimidine Asreported 14631-08-4 2g $1204 2026-06-03 Buy
Usbiological 267644 2-Chloro-4,5-diaminopyrimidine Asreported 14631-08-4 5g $2018 2026-06-03 Buy
Product number Packaging Price Buy
267644 250mg $396 Buy
267644 500mg $581 Buy
267644 1g $835 Buy
267644 2g $1204 Buy
267644 5g $2018 Buy

2-Chloro-4,5-diaminopyrimidine Chemical Properties,Uses,Production

Synthesis

A mixture of 2-chloro-5-nitropyrimidin-4-amine (1.0 g, 5.7 mmol) and SnCl2·2H2O (5.2 g, 22.9 mmol) in EtOH (55 mL) under N2 was heated to 80 °C and stirred for two hours. The mixture was then concentrated under reduced pressure. EtOAc and Celite were added to the residue, and the mixture was basified with saturated Na2CO3 (aq.) to pH 9- 10. The mixture was filtered through a pad of Celite and washed with EtOAc. The organic layer was separated, washed with brine, dried (Na2SO4), and concentrated in a vacuum. The residue was purified on ISCO (20 g silica gel column, EtOAc/hexanes 0~100 per cent) to give 2-Chloro-4,5-diaminopyrimidine (0.41 g 49 per cent).

References

[1] Patent: US2017/313683, 2017, A1. Location in patent: Paragraph 0544
[2] Patent: WO2016/171755, 2016, A1. Location in patent: Paragraph 0176
[3] Journal of Organic Chemistry, 1955, vol. 20, p. 829,833,835
[4] Nature (London, United Kingdom), 1948, vol. 162, p. 524
[5] Journal of the Chemical Society, 1951, p. 474,478

2-Chloro-4,5-diaminopyrimidine synthesis

1920-66-7
14631-08-4
Synthesis of 2-Chloro-4,5-diaminopyrimidine from 2-Chloro-5-nitropyrimidin-4-amine

2-Chloro-4,5-diaminopyrimidine Preparation Products And Raw materials

Raw materials

5-Nitrouracil Ammonium hydroxide Nickel Phosphorus oxitrichloride N,N-Diethylaniline
2-Chloro-5-nitropyrimidin-4-amine Ethanol Ammonium chloride Water Iron

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Preparation Products

2-Chloropurine

2-Chloro-4,5-diaminopyrimidine Suppliers

Global( 139)Suppliers
Supplier Tel Email Country ProdList Advantage
Fuyang JSK Biomedical Technology Co., Ltd 18915409046 1102409417@qq.com China 203 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
ZEROSCHEM.CO.,LTD. 10-61256048 13810278579; sales@zeroschem.com China 1399 59
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
EnciPharmatech Co., Ltd 025-52714267-66 13813902930 stephen_shengll@hotmail.com China 231 64
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Supplier Advantage
Fuyang JSK Biomedical Technology Co., Ltd 55
J & K SCIENTIFIC LTD. 76
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Jia Xing Isenchem Co.,Ltd 66
Pure Chemistry Scientific Inc. 62
ZEROSCHEM.CO.,LTD. 59
Nanjing Chemlin Chemical Co., Ltd 64
EnciPharmatech Co., Ltd 64
Shanghai T&W Pharmaceutical Co., Ltd. 58

View Lastest Price from 2-Chloro-4,5-diaminopyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLORO-4,5-DIAMINOPYRIMIDINE pictures 2026-08-20 2-CHLORO-4,5-DIAMINOPYRIMIDINE
14631-08-4
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-CHLORO-4,5-DIAMINOPYRIMIDINE pictures 2021-08-12 2-CHLORO-4,5-DIAMINOPYRIMIDINE
14631-08-4
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2-Chloro-4,5-diamino pyrimidine pictures 2021-07-13 2-Chloro-4,5-diamino pyrimidine
14631-08-4
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

2-Chloro-4,5-diaminopyrimidine Spectrum

2-Chloro-4,5-diaminopyrimidine(14631-08-4)MS2-Chloro-4,5-diaminopyrimidine(14631-08-4)1HNMR2-Chloro-4,5-diaminopyrimidine(14631-08-4)IR12-Chloro-4,5-diaminopyrimidine(14631-08-4)IR2

14631-08-4(2-Chloro-4,5-diaminopyrimidine)Related Search:

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IFLAB-BB F1371-0155 2-CHLORO-4,5-DIAMINOPYRIMIDINE 4,5-DIAMINO-2-CHLOROPYRIMIDINE (4-amino-2-chloro-pyrimidin-5-yl)amine 4,5-Pyrimidinediamine, 2-chloro- (9CI) 2-CHLORO-4,5-DIAMONOPYRIMIDINE 6-Chloro-2,3-PyriMidinediaMine (4-amino-2-chloro-pyrimidin-5-yl)amin 4,5-Pyrimidinediamine, 2-chloro- 2-CHLORO-4,5-DIAMINOPYRIMIDINE ISO 9001：2015 REACH 2-CHLOROPYRIMIDINE-4,5-DIAMINE 14631-08-4 Heterocycle-Pyrimidine series PYRIMIDINE APIs & Intermediate pharmacetical Building Blocks