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2-Chlorothiophene

CAS No.
96-43-5
Chemical Name:
2-Chlorothiophene
Synonyms
THIENYL CHLORIDE;orothiophene;ChloroThiophene;2-Chlorthiophen;2-Chlorothiphene;2-Chlrothiophene;2-chloro-thiophen;2-CHLOROTHIOPHENE;2-THIENYL CHLORIDE;thiophene,2-chloro-
CBNumber:
CB1265028
Molecular Formula:
C4H3ClS
Molecular Weight:
118.58
MDL Number:
MFCD00005421
MOL File:
96-43-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:23:07

2-Chlorothiophene Properties

Melting point -71.9 °C
Boiling point 127-129 °C (lit.)
Density 1.286 g/mL at 25 °C (lit.)
refractive index n20/D 1.547(lit.)
Flash point 73 °F
storage temp. 2-8°C
solubility soluble in Chloroform
form Liquid
color Clear colorless to light brown
Specific Gravity 1.286
Water Solubility INSOLUBLE
BRN 104652
Stability Volatile
InChI 1S/C4H3ClS/c5-4-2-1-3-6-4/h1-3H
InChIKey GSFNQBFZFXUTBN-UHFFFAOYSA-N
SMILES Clc1cccs1
CAS DataBase Reference 96-43-5(CAS DataBase Reference)
FDA UNII 3EVV74IJN6
NIST Chemistry Reference Thiophene, 2-chloro-(96-43-5)
EPA Substance Registry System Thiophene, 2-chloro- (96-43-5)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)Skull and Crossbones (GHS06)
GHS02,GHS07,GHS06
Signal word  Warning
Hazard statements  H302-H226-H315-H319-H335-H225-H301-H311-H331
Precautionary statements  P301+P310a-P303+P361+P353-P405-P501a-P210-P233-P240-P241+P242+P243-P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P403+P235-P501-P261-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi,F,T
Risk Statements  10-36/37/38-23/24/25-37
Safety Statements  16-26-36-45-38-36/37/39-28B-7/9
RIDADR  UN 1993 3/PG 3
WGK Germany  3
RTECS  XM8575000
Hazard Note  Irritant
TSCA  TSCA listed
HazardClass  3
PackingGroup  II
HS Code  29349990
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3
REACH Registrations Active
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
3
2 0

2-Chlorothiophene price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C0807 2-Chlorothiophene >98.0%(GC) 96-43-5 25g $27 2026-04-30 Buy
TRC TRC-C428908-500MG 2-Chlorothiophene 96-43-5 500mg $94 2026-06-03 Buy
TRC TRC-C428908-250MG 2-Chlorothiophene 96-43-5 250mg $70 2026-06-03 Buy
TRC TRC-C428908-2.5G 2-Chlorothiophene 96-43-5 2.5g $120 2026-06-03 Buy
Apolloscientific OR10138 2-Chlorothiophene 98% 96-43-5 5g $21 2026-06-04 Buy
Product number Packaging Price Buy
C0807 25g $27 Buy
TRC-C428908-500MG 500mg $94 Buy
TRC-C428908-250MG 250mg $70 Buy
TRC-C428908-2.5G 2.5g $120 Buy
OR10138 5g $21 Buy

2-Chlorothiophene Chemical Properties,Uses,Production

Chemical Properties

Colorless to light yellow liquid

Uses

2-Chlorothiophene was used in the preparation of 5-phenylthiophene derivative.

Application

2-Chlorothiophene is a heterocyclic compound that belongs to the group of organic compounds called thiophenes. It is an effective analgesic and anti-inflammatory drug that has been used in the treatment of inflammatory bowel disease. 2-Chlorothiophene is used as a reagent in chemical synthesis, especially the preparation of pharmaceutical preparations. This compound can be prepared by photoelectron or hydrochloric acid. The suzuki coupling reaction with pyrimidine compounds is another method for synthesizing this compound.

General Description

The photodissociation dynamics of 2-chlorothiophene was studied using resonance enhanced multiphoton ionization (REMPI) time-of-flight (TOF) technique.

Purification Methods

Purify it by fractional distillation at atmospheric pressure or by gas chromatography. [Conde et al. Synthesis 412 1976, Beilstein 17/1 V 303.]

188290-36-0
96-43-5
Synthesis of 2-Chlorothiophene from Thiophene(SIV) (9CI)
Global( 437)Suppliers
Supplier Tel Email Country ProdList Advantage
Weifang Siyuan Chemical Co., Ltd. 0536-8888106 17663601818 2354379876@qq.com China 244 58
Zouping Innovation Pharmaceutical Co., Ltd. 13561560789 xinxiaoxiao2008@126.com China 686 58
Xi 'an Jiuqi Biotechnology Co., LTD 18729366352 13186100227 3147904319@qq.com China 61 58
Guangdong Shengke Biochemical Technology Co., Ltd. 18925113981 18925113981 3809205144@qq.com China 4069 58
Qingdao Frontierchem Co.,Ltd. 0532-88320311 15966837432 sales@qdfrontierchem.com China 14 57
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81

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2-Chlorothiophene pictures 2026-09-02 2-Chlorothiophene
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$9.00 1KG 99% Henan Fengda Chemical Co., Ltd
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$10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
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$1.00 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
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