2-Chlorothiophene
- CAS No.
- 96-43-5
- Chemical Name:
- 2-Chlorothiophene
- Synonyms
- THIENYL CHLORIDE;orothiophene;ChloroThiophene;2-Chlorthiophen;2-Chlorothiphene;2-Chlrothiophene;2-chloro-thiophen;2-CHLOROTHIOPHENE;2-THIENYL CHLORIDE;thiophene,2-chloro-
- CBNumber:
- CB1265028
- Molecular Formula:
- C4H3ClS
- Molecular Weight:
- 118.58
- MDL Number:
- MFCD00005421
- MOL File:
- 96-43-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | -71.9 °C |
|---|---|
| Boiling point | 127-129 °C (lit.) |
| Density | 1.286 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 73 °F |
| storage temp. | 2-8°C |
| solubility | soluble in Chloroform |
| form | Liquid |
| color | Clear colorless to light brown |
| Specific Gravity | 1.286 |
| Water Solubility | INSOLUBLE |
| BRN | 104652 |
| Stability | Volatile |
| InChI | 1S/C4H3ClS/c5-4-2-1-3-6-4/h1-3H |
| InChIKey | GSFNQBFZFXUTBN-UHFFFAOYSA-N |
| SMILES | Clc1cccs1 |
| CAS DataBase Reference | 96-43-5(CAS DataBase Reference) |
| FDA UNII | 3EVV74IJN6 |
| NIST Chemistry Reference | Thiophene, 2-chloro-(96-43-5) |
| EPA Substance Registry System | Thiophene, 2-chloro- (96-43-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() ![]() GHS02,GHS07,GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H226-H315-H319-H335-H225-H301-H311-H331 | |||||||||
| Precautionary statements | P301+P310a-P303+P361+P353-P405-P501a-P210-P233-P240-P241+P242+P243-P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P403+P235-P501-P261-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,F,T | |||||||||
| Risk Statements | 10-36/37/38-23/24/25-37 | |||||||||
| Safety Statements | 16-26-36-45-38-36/37/39-28B-7/9 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XM8575000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Flam. Liq. 3 Skin Irrit. 2 STOT SE 3 |
|||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
2-Chlorothiophene price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C0807 | 2-Chlorothiophene >98.0%(GC) | 96-43-5 | 25g | $27 | 2026-04-30 | Buy |
| TRC | TRC-C428908-500MG | 2-Chlorothiophene | 96-43-5 | 500mg | $94 | 2026-06-03 | Buy |
| TRC | TRC-C428908-250MG | 2-Chlorothiophene | 96-43-5 | 250mg | $70 | 2026-06-03 | Buy |
| TRC | TRC-C428908-2.5G | 2-Chlorothiophene | 96-43-5 | 2.5g | $120 | 2026-06-03 | Buy |
| Apolloscientific | OR10138 | 2-Chlorothiophene 98% | 96-43-5 | 5g | $21 | 2026-06-04 | Buy |
2-Chlorothiophene Chemical Properties,Uses,Production
Chemical Properties
Colorless to light yellow liquid
Uses
2-Chlorothiophene was used in the preparation of 5-phenylthiophene derivative.
Application
2-Chlorothiophene is a heterocyclic compound that belongs to the group of organic compounds called thiophenes. It is an effective analgesic and anti-inflammatory drug that has been used in the treatment of inflammatory bowel disease. 2-Chlorothiophene is used as a reagent in chemical synthesis, especially the preparation of pharmaceutical preparations. This compound can be prepared by photoelectron or hydrochloric acid. The suzuki coupling reaction with pyrimidine compounds is another method for synthesizing this compound.
General Description
The photodissociation dynamics of 2-chlorothiophene was studied using resonance enhanced multiphoton ionization (REMPI) time-of-flight (TOF) technique.
Purification Methods
Purify it by fractional distillation at atmospheric pressure or by gas chromatography. [Conde et al. Synthesis 412 1976, Beilstein 17/1 V 303.]
2-Chlorothiophene Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Weifang Siyuan Chemical Co., Ltd. | 0536-8888106 17663601818 | 2354379876@qq.com | China | 244 | 58 |
| Zouping Innovation Pharmaceutical Co., Ltd. | 13561560789 | xinxiaoxiao2008@126.com | China | 686 | 58 |
| Xi 'an Jiuqi Biotechnology Co., LTD | 18729366352 13186100227 | 3147904319@qq.com | China | 61 | 58 |
| Guangdong Shengke Biochemical Technology Co., Ltd. | 18925113981 18925113981 | 3809205144@qq.com | China | 4069 | 58 |
| Qingdao Frontierchem Co.,Ltd. | 0532-88320311 15966837432 | sales@qdfrontierchem.com | China | 14 | 57 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
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- Feb 27,2026
View Lastest Price from 2-Chlorothiophene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-02 | 2-Chlorothiophene
96-43-5
|
$9.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
![]() |
2026-03-20 | 2-Chlorothiophene
96-43-5
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
![]() |
2026-02-02 | 2-Chlorothiophene
96-43-5
|
$1.00 | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd |
-

- 2-Chlorothiophene
96-43-5
- $9.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 2-Chlorothiophene
96-43-5
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 2-Chlorothiophene
96-43-5
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd









