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2-Chloro-5-chloromethylthiophene

CAS No.
23784-96-5
Chemical Name:
2-Chloro-5-chloromethylthiophene
Synonyms
CAS#23784-96-5;5-Chloro-2-thenyl chloride;2-CHLORO-5-(CHLOROMETHYL)THIOPHENE;2-CHLORO-5-CHLOROMETHYLTHIOPHENE 98+%;Thiophene, 2-chloro-5-(chloromethyl)-;2-Chloro-5-(chloromethyl)thiophene,97%
CBNumber:
CB5184334
Molecular Formula:
C5H4Cl2S
Molecular Weight:
167.06
MDL Number:
MFCD00009764
MOL File:
23784-96-5.mol
MSDS File:
SDS
Last updated:2026-05-28 02:50:37
Product description Number Pack Size Price
2-Chloro-5-(chloromethyl)thiophene 97% 241822 1g $72.7
2-Chloro-5-(chloromethyl)thiophene 97% 241822 5g $249
2-Chloro-5-(chloromethyl)thiophene >97% OR350104 1g $21
2-Chloro-5-(chloromethyl)thiophene >97% OR350104 5g $59
2-Chloro-5-(chloromethyl)thiophene >97% OR350104 25g $287

2-Chloro-5-chloromethylthiophene Properties

Boiling point 83-85 °C8 mm Hg(lit.)
Density 1.385 g/mL at 25 °C(lit.)
refractive index n20/D 1.575(lit.)
Flash point 213 °F
storage temp. -20°C
form Liquid
color Colorless to brown
InChI 1S/C5H4Cl2S/c6-3-4-1-2-5(7)8-4/h1-2H,3H2
InChIKey MQTKXCOGYOYAMW-UHFFFAOYSA-N
SMILES ClCc1ccc(Cl)s1
CAS DataBase Reference 23784-96-5(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3
HS Code  29349990
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
3 1

2-Chloro-5-chloromethylthiophene price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 241822 2-Chloro-5-(chloromethyl)thiophene 97% 23784-96-5 1g $72.7 2023-06-20 Buy
Sigma-Aldrich 241822 2-Chloro-5-(chloromethyl)thiophene 97% 23784-96-5 5g $249 2023-06-20 Buy
Apolloscientific OR350104 2-Chloro-5-(chloromethyl)thiophene >97% 23784-96-5 1g $21 2026-06-04 Buy
Apolloscientific OR350104 2-Chloro-5-(chloromethyl)thiophene >97% 23784-96-5 5g $59 2026-06-04 Buy
Apolloscientific OR350104 2-Chloro-5-(chloromethyl)thiophene >97% 23784-96-5 25g $287 2026-06-04 Buy
Product number Packaging Price Buy
241822 1g $72.7 Buy
241822 5g $249 Buy
OR350104 1g $21 Buy
OR350104 5g $59 Buy
OR350104 25g $287 Buy

2-Chloro-5-chloromethylthiophene Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to yellow liquid

Uses

2-Chloro-5-(chloromethyl)thiophene was used in the synthesis of 1-(1,1′-biphenyl-4-yl)-3-(5-chloro-thiophen-2-yl)-2-(1H-imidazol-1-yl)propane and 1-(5-chlorothiophen-2-yl)-2-(1H-imidazol-1-yl)-3-phenylpropane.

Synthesis

5-Chlorothiophene-2-ylmethanol

74168-69-7

2-Chloro-5-chloromethylthiophene

23784-96-5

Under nitrogen protection, 5-chloro-2-thiophene methanol (500 mg, 3.37 mmol) was dissolved in tetrahydrofuran (10 mL) and cooled to 0 °C. Subsequently, CN (482 mg, 4.05 mmol) was added dropwise. After the dropwise addition, the reaction mixture was warmed up to 50 °C for 3 h, during which the reaction progress was monitored by TLC. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to afford 480 mg of 2-chloro-5-chloromethylthiophene in yellow liquid form (yield: 85.5%), which could be used directly in the subsequent reaction without further purification.

References

[1] Patent: CN107188865, 2017, A. Location in patent: Paragraph 0113; 0116; 0117

2-Chloro-5-chloromethylthiophene Preparation Products And Raw materials

2-Chloro-5-chloromethylthiophene Suppliers

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View Lastest Price from 2-Chloro-5-chloromethylthiophene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-5-chloromethylthiophene pictures 2020-01-08 2-Chloro-5-chloromethylthiophene
23784-96-5
$1.00 1g 99.0% 100kg Career Henan Chemical Co
2-CHLORO-5-(CHLOROMETHYL)THIOPHENE 2-CHLORO-5-CHLOROMETHYLTHIOPHENE 98+% 5-Chloro-2-thenyl chloride 2-Chloro-5-(chloromethyl)thiophene,97% Thiophene, 2-chloro-5-(chloromethyl)- CAS#23784-96-5 23784-96-5 23784-90-5 Building Blocks Heterocyclic Building Blocks Halogenated Heterocycles Thiophenes BENZYL HALIDE Sulfur Halogenated Heterocycles Heterocyclic Building Blocks Thiophenes ThiophenesBuilding Blocks Sulphur Derivatives