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Fleroxacin

Fleroxacin Structure
Fleroxacin structure
CAS No.
79660-72-3
Chemical Name:
Fleroxacin
Synonyms
AM-833;QUINODIS;MEGALONE;MEGALOCIN;RO-23-6240;FLEROXACIN;ro23-6240/000;Fleroxacin>Erlotinib-d12 HCl;Fleroxacin, >=99%
CBNumber:
CB1331989
Molecular Formula:
C17H18F3N3O3
Molecular Weight:
369.34
MDL Number:
MFCD00864880
MOL File:
79660-72-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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Fleroxacin Properties

Melting point 264-266°C
Boiling point 535.3±50.0 °C(Predicted)
Density 1.409±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility 0.1 M NaOH: soluble10mg/mL
pka -0.54±0.20(Predicted)
form solid
color white to off-white
Merck 14,4099
InChI InChI=1S/C17H18F3N3O3/c1-21-4-6-22(7-5-21)15-12(19)8-10-14(13(15)20)23(3-2-18)9-11(16(10)24)17(25)26/h8-9H,2-7H2,1H3,(H,25,26)
InChIKey XBJBPGROQZJDOJ-UHFFFAOYSA-N
SMILES N1(CCF)C2=C(C=C(F)C(N3CCN(C)CC3)=C2F)C(=O)C(C(O)=O)=C1
CAS DataBase Reference 79660-72-3(CAS DataBase Reference)
FDA UNII N804LDH51K
ATC code J01MA08
UNSPSC Code 51102829
NACRES NA.85

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Warning
Hazard statements  H371
Precautionary statements  P260-P264-P270-P308+P311-P405-P501
WGK Germany  2
RTECS  VB1999050
HS Code  29335990
Storage Class 11 - Combustible Solids

Fleroxacin price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F6807 Fleroxacin ≥98% (HPLC) 79660-72-3 1g $631 2023-06-20 Buy
Sigma-Aldrich 33930 Fleroxacin VETRANAL?, analytical standard 79660-72-3 100MG $122 2022-05-15 Buy
TCI Chemical F0646 Fleroxacin >98.0%(T) 79660-72-3 5g $108 2026-04-30 Buy
TCI Chemical F0646 Fleroxacin >98.0%(T) 79660-72-3 25g $336 2026-04-30 Buy
Cayman Chemical 24173 Fleroxacin ≥98% 79660-72-3 1g $63 2026-04-30 Buy
Product number Packaging Price Buy
F6807 1g $631 Buy
33930 100MG $122 Buy
F0646 5g $108 Buy
F0646 25g $336 Buy
24173 1g $63 Buy

Fleroxacin Chemical Properties, Uses, Production

Description

Fleroxacin is a new, once daily trifluoroquinolone antibacterial structurally related to norfloxacin. Available in both oral and IV formulations, it is reportedly useful in the treatment of gonorrhea, bacterial enteritis, chronic bronchitis and urinary tract infections. Fleroxacin has a longer serum half-life (9-12 hours) than other drugs of this class, such as ciprofloxacin, enoxacin and norfloxacin.

Chemical Properties

White Needle-Like Crystals

Originator

Kyorin (Japan)

Uses

An antibacterial.

Uses

antibiotic

Definition

ChEBI: A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-n gative bacteria.

Manufacturing Process

6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4- oxoquinoline-3-carboxylic acid hydrochloride:
A mixed solution of 1-methylpiperazine (0.34 g) and pyridine (3 ml) was added to 6,7,8-trifluoro-1-(2-fluoroethyl)-1,4-dihydro-4-oxoquinoline-3- carboxylic acid (0.12 g) and heated to reflux for 6 hours. After the solvent evaporated and cooled, the residue was adjusted to pH 1 with aqueous hydrochloric acid. The cooled mixture was filtered off and the solid recrystallized from water to give 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7- (4-methyl-1-piperazinyl)-4-oxoquinoline-3-carboxylic acid hydrochloride (0.08 g), melting point 269-271°C (decomp.).

brand name

Quinodis

Therapeutic Function

Antibacterial

Fleroxacin Preparation Products And Raw materials

Raw materials

Fluorobromoethane 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester Quinoline-3-carboxylic acid Ethanol 2,3,4-Trifluorobenzenamine
Acetic anhydride Diethyl ethoxymethylenemalonate Potassium carbonate 1-Methylpiperazine

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Preparation Products

Fleroxacin Suppliers

Global Suppliers ( 314)
Supplier Tel Email Country ProdList Advantage
Tianfang Pharmaceutical Co., Ltd. -- tfyy@topfond.com China 21 58
Hunan ravel Biotechnology Co.,Ltd 18086085632 435918333@qq.com China 1926 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Supplier Advantage
Tianfang Pharmaceutical Co., Ltd. 58
Hunan ravel Biotechnology Co.,Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
3B Pharmachem (Wuhan) International Co.,Ltd. 69
TAIYUAN RHF CO.,LTD. 56
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Pure Chemistry Scientific Inc. 62
Shanghai Longsheng chemical Co.,Ltd. 59

Related articles

  • Uses of Fleroxacin
  • Fleroxacin (Ro 23-6240, AM 833) is different from fluoroquinolones such as ciprofloxacin or ofloxacin, since it is a trifluori....
  • Mar 25,2022

View Latest Price from Fleroxacin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fleroxacin pictures 2026-09-02 Fleroxacin
79660-72-3
 $1.20-36.00 1kg 99% Henan Fengda Chemical Co., Ltd
Fleroxacin USP/EP/BP pictures 2026-08-20 Fleroxacin USP/EP/BP
79660-72-3
 $1.10 1g 99.9% 100 Tons min Dideu Industries Group Limited
Fleroxacin pictures 2026-07-15 Fleroxacin
79660-72-3
 $40.00 99.79% 10g TargetMol Chemicals Inc.
  • Fleroxacin pictures
  • Fleroxacin
    79660-72-3
  • $1.20-36.00
  • 99%
  • Henan Fengda Chemical Co., Ltd
  • Fleroxacin pictures
  • Fleroxacin
    79660-72-3
  • $40.00
  • 99.79%
  • TargetMol Chemicals Inc.

Fleroxacin Spectrum

Fleroxacin(79660-72-3)1HNMR

79660-72-3 (Fleroxacin) Related Search:

4-(Diethylamino)salicylaldehyde 5-Chlorovaleric acid GHRP-2 Methyl 2-hydroxyethyl cellulose Dihydromyrcenol
DL-α-Tocopherol N-Aminoethylpiperazine Diphenolic acid (2-Methoxyethyl)benzene 1-Methylpiperazine
FLEROXACINLACTATE 3-(4-Methylpiperazin-1-yl)aniline Pefloxacin 2-Butanone 4-Amino-3,5-difluoroacetophenone
Norfloxacin MAGNESIUM PERCHLORATE HEXAHYDRATE IRON(III) PERCHLORATE HYDRATE

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Erlotinib-d12 HCl 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid AM-833, Ro-23-6240, Megalocin, Megalone, Quinodis, 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid AM-833, Megalocin, Megalone, 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methylpiperazino)-4-oxo-3-quinolinecarboxylic acid, 6,8-Difluoro-1-(2-fluoroethyl)1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-4-oxo-7-(4-methyl-1-piperazinyl)quinoline-3-carboxylic acid 6,8-difluoro-1-(2-fluoroethyl)-4-keto-7-(4-methylpiperazin-1-yl)quinoline-3-carboxylic acid 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylicacid 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Megalone Fleroxacin Solution, 100ppm RO-23-6240 QUINODIS 3-quinolinecarboxylicacid,1,4-dihydro-6,8-difluoro-1-(2-fluoroethyl)-7-(4-met hyl-1-piperazinyl)-4-oxo- ro23-6240/000 Fleroxacin solution,1000ppm Fleroxacin, >=99% FLEROXACIN MEGALOCIN MEGALONE AM-833 6,8-DIFLUORO-1-(2-FLUOROETHYL)-1,4-DIHYDRO-7-(4-METHYL-1-PIPERAZINYL)-4-OXO-3-QUINOLINECARBOXYLIC ACID 6,8-DIFLUORO-1-(2-FLUOROETHYL)-1,4-DIHYDRO-7-(4-METHYLPIPERAZINO)-4-OXO-3-QUINOLINECARBOXYLIC ACID Fleroxacin> Fleroxacin Fleroxacin Fleroxacin, 98%, for analysis 3-Quinolinecarboxylic acid, 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo- Fleroxacin USP/EP/BP 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-4-ium-1-yl)-4-oxoquinoline-3-carboxylate 6,8-Difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Fluorine Rosa star 6,8-Difluoro-1-(2-fluoroethyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid C13658000 Fleroxacin Fleroxacin in Methanol Fleroxacin (Standard) 79660-72-3 79960-72-3 79660-72-7 C17H18F3NC3H6O3 C17H18F3N3O3 Quinodis, Megalocin Antibiotics for Research and Experimental Use Biochemistry Quinolones (Antibiotics for Research and Experimental Use) Intermediates & Fine Chemicals Pharmaceuticals