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BISINDOLYLMALEIMIDE II

BISINDOLYLMALEIMIDE II structure

CAS No.: 137592-45-1

Chemical Name:: BISINDOLYLMALEIMIDE II

Synonyms: BISINDOLYLMALEIMIDE II;Bisindolylmaleimide II, PKC inhibitor;2-[1-[2-(1-METHYLPYRROLIDINO)ETHYL]-1H-INDOL-3-YL]-3-(1H-INDOL-3-YL)MALEIMIDE;3-(1H-indol-3-yl)-4-[1-[2-(1-methylpyrrolidin-2-yl)ethyl]indol-3-yl]pyrrole-2,5-dione;3-(1H-Indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-

CBNumber:: CB2458955

Molecular Formula:: C27H26N4O2

Molecular Weight:: 438.52

MDL Number:: MFCD00236430

MOL File:: Mol file

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:27

Product description	Number	Pack Size	Price
Bisindolylmaleimide II ≥97% (Mixture of 2 isomers)	B3056	1 mg	$154
Bisindolylmaleimide II ≥97%(isomermixture)	11020	1mg	$63
Bisindolylmaleimide II ≥97%(isomermixture)	11020	5mg	$190
Bisindolylmaleimide II Asreported	254776	10mg	$466
Bisindolylmaleimide II Asreported	254776	50mg	$1281

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BISINDOLYLMALEIMIDE II Properties

Boiling point	709.9±60.0 °C(Predicted)
Density	1.36±0.1 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMSO: soluble
form	solid
pka	8.17±0.60(Predicted)
color	Yellow to orange
biological source	synthetic (organic)
InChIKey	LBFDERUQORUFIN-UHFFFAOYSA-N
SMILES	CN1CCCC1CCn2cc(C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45)c6ccccc26
UNSPSC Code	12352111
NACRES	NA.77

SAFETY

Risk and Safety Statements

PPE	Eyeshields, Gloves, type N95 (US)
WGK Germany	3
Storage Class	11 - Combustible Solids

BISINDOLYLMALEIMIDE II price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	B3056	Bisindolylmaleimide II ≥97% (Mixture of 2 isomers)	137592-45-1	1 mg	$154	2026-04-30	Buy
Cayman Chemical	11020	Bisindolylmaleimide II ≥97%(isomermixture)	137592-45-1	1mg	$63	2026-04-30	Buy
Cayman Chemical	11020	Bisindolylmaleimide II ≥97%(isomermixture)	137592-45-1	5mg	$190	2026-04-30	Buy
Usbiological	254776	Bisindolylmaleimide II Asreported	137592-45-1	10mg	$466	2026-06-03	Buy
Usbiological	254776	Bisindolylmaleimide II Asreported	137592-45-1	50mg	$1281	2026-06-03	Buy

Product number	Packaging	Price	Buy
B3056	1 mg	$154	Buy
11020	1mg	$63	Buy
11020	5mg	$190	Buy
254776	10mg	$466	Buy
254776	50mg	$1281	Buy

BISINDOLYLMALEIMIDE II Chemical Properties,Uses,Production

Uses

Bisindolylmaleimide II, is a potent ATP-competitive protein kinase C (PKC) inhibitor. In addition it inhibits PDK1 (IC50 = 14 μM), an important kinase in the insulin signaling pathway, and PKA (IC50 = 2.94 μM).

Biological Activity

Bisindolylmaleimide II (BIS II) acts as a dual protein kinase A/C (PKA/C) inhibitor.

storage

-20°C

BISINDOLYLMALEIMIDE II Preparation Products And Raw materials

Raw materials

Preparation Products

BISINDOLYLMALEIMIDE II Suppliers

Global( 42)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
Aladdin Scientific		tp@aladdinsci.com	United States	50108	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
BOC Sciences	--	info@bocsci.com	USA	0	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11123	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24951	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	5987	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
BOC Sciences	58
Aladdin Scientific	58
Shanghai EFE Biological Technology Co., Ltd.	58
BOC Sciences	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Nantong QuanYi Biotechnology Co., Ltd	58

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BISINDOLYLMALEIMIDE II 3-(1H-Indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione 2-[1-[2-(1-METHYLPYRROLIDINO)ETHYL]-1H-INDOL-3-YL]-3-(1H-INDOL-3-YL)MALEIMIDE 3-(1H-indol-3-yl)-4-[1-[2-(1-methylpyrrolidin-2-yl)ethyl]indol-3-yl]pyrrole-2,5-dione 1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]- Bisindolylmaleimide II, PKC inhibitor 137592-45-1 Cell Signaling and Neuroscience Cell Biology BioChemical Serine/Threonine Kinase Inhibitors Kinase/Phosphatase Biology Protein Kinase C (PKC) Enzyme Inhibitors by Enzyme Kinase/Phosphatase Biology P to Protein Kinase C (PKC)Cell Signaling and Neuroscience Protein kinase CSerine/Threonine Kinase Biology Protein Kinase Inhibitors Protein Kinase InhibitorsPeptides for Cell Biology Protein Kinase Related Peptides Serine/Threonine Kinase Inhibitors