ChemicalBook >> CAS DataBase List >>2,2,2-Trifluoroethyl p-toluenesulfonate

2,2,2-Trifluoroethyl p-toluenesulfonate

CAS No.
433-06-7
Chemical Name:
2,2,2-Trifluoroethyl p-toluenesulfonate
Synonyms
2,2,2-TRIFLUOROETHYL 4-METHYLBENZENESULFONATE;2,2,2-trifluoroethyl ester;100532;TRIFLUORETHYLTOSYLATE;Trifluoroethyltosylate;Azithromycin Impurity 74;TRIFLUOROETHANOL TOSYLATE;2,2,2-TRIFLUOROETHYL P-TO;2,2,2-TRIFLUOROETHYL TOSYLATE;o-(p-tosyl)a,a,a,-trifluoroethanol
CBNumber:
CB2670852
Molecular Formula:
C9H9F3O3S
Molecular Weight:
254.23
MDL Number:
MFCD00000443
MOL File:
433-06-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:51:23

2,2,2-Trifluoroethyl p-toluenesulfonate Properties

Melting point 36-38 °C(lit.)
Boiling point 87-92 °C0.1 mm Hg(lit.)
Density 1 g/cm3
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Sparingly), Methanol (Sparingly)
form Solid
color White to Off-White
Sensitive Moisture Sensitive
BRN 2699394
Stability Hygroscopic
InChI 1S/C9H9F3O3S/c1-7-2-4-8(5-3-7)16(13,14)15-6-9(10,11)12/h2-5H,6H2,1H3
InChIKey IGKCQDUYZULGBM-UHFFFAOYSA-N
SMILES Cc1ccc(cc1)S(=O)(=O)OCC(F)(F)F
CAS DataBase Reference 433-06-7(CAS DataBase Reference)
NIST Chemistry Reference Ethanol, 2,2,2-trifluoro-, 4-methylbenzenesulfonate(433-06-7)
EPA Substance Registry System Ethanol, 2,2,2-trifluoro-, 4-methylbenzenesulfonate (433-06-7)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29049090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

2,2,2-Trifluoroethyl p-toluenesulfonate price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 177822 2,2,2-Trifluoroethyl p-toluenesulfonate 99% 433-06-7 50g $119 2026-04-30 Buy
TCI Chemical T1516 2,2,2-Trifluoroethyl p-Toluenesulfonate >98.0%(GC)(T) 433-06-7 25g $101 2026-04-30 Buy
TRC TRC-T790230-50G 2,2,2-Trifluoroethyl Tosylate 433-06-7 50g $91 2026-06-03 Buy
TRC TRC-T790230-250G 2,2,2-Trifluoroethyl Tosylate 433-06-7 250g $302 2026-06-03 Buy
TRC TRC-T790230-100G 2,2,2-Trifluoroethyl Tosylate 433-06-7 100g $154 2026-06-03 Buy
Product number Packaging Price Buy
177822 50g $119 Buy
T1516 25g $101 Buy
TRC-T790230-50G 50g $91 Buy
TRC-T790230-250G 250g $302 Buy
TRC-T790230-100G 100g $154 Buy

2,2,2-Trifluoroethyl p-toluenesulfonate Chemical Properties, Uses, Production

Chemical Properties

WHITE CRYSTALLINE SOLID

Uses

2,2,2-Trifluoroethyl Tosylate is a trifluoroethylation agent used in the preparation of 2,2,2-trifluoroethyl phenyl sulfone, a potential 2,2,2-trifluoroethyl pronucleophile.

Synthesis

2,2,2-Trifluoroethyl p-Toluenesulfonate is easily prepared by treating 2,2,2-trifluoroethanol with p-Toluenesulfonyl Chloride in pyridine or in aqueous acetone containing NaOH.

Precautions

Quite stable; can be handled without any special technique and stored at room temperature; use in a fume hood.

Global Suppliers ( 244)
Supplier Tel Email Country ProdList Advantage
Xinlian Rui Biomedical Technology (Shandong) Co., Ltd 0531-84567878 15153173989 3865799121@qq.com China 79 58
Jiaxing Fubo Biotechnology Co., Ltd. 156-571-11153 18157018567; sales@fluorio.com China 93 58
SHANG FLUORO 021-65170832 15601903708 qinba_1@163.com China 401 60
Shandong Zhishang Chemical Co. LTD 15689709505 15508639737 2138533552@qq.com China 102 58
Shandong Libixi Biopharmaceutical Technology Co., Ltd. 15318973357; 15318973357 1460285141@qq.com China 9642 58
Suzhou Lakestar Pharmatech Co., Ltd. 0512-63970158-603 18018108880 info@lakestarpharma.com China 401 59
Shenyang Feikai Chemical Technology Co., Ltd. 13840042777 13889276367 40825993@qq.com China 6 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69

View Latest Price from 2,2,2-Trifluoroethyl p-toluenesulfonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2,2-trifluoroethyl tosylate pictures 2026-08-25 2,2,2-trifluoroethyl tosylate
433-06-7
$3.90-5.90 1KG 99% ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
222-TRIFLUOROETHYL P-TOLUENESULFONATE  pictures 2026-08-07 222-TRIFLUOROETHYL P-TOLUENESULFONATE
433-06-7
$1.00-100.00 1KG 99% 300KG Shaanxi Dideu Medichem Co. Ltd
Trifluoroethyl p-toluene sulfonate pictures 2026-05-28 Trifluoroethyl p-toluene sulfonate
433-06-7
$9.00 1KG 99% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
TRIFLUORETHYLTOSYLATE TRIFLUOROETHANOL TOSYLATE P-TOLUENESULFONIC ACID 2,2,2-TRIFLUOROETHYL ESTER 2,2,2-trifluoro-, p-toluenesulfonate o-(p-tosyl)a,a,a,-trifluoroethanol 2,2,2-Trifluoroethyl 4-methylbenzenesulphonate, 2,2,2-Trifluoroethyl tosylate 2,2,2-Trifluoroethyl toluene-4-sulphonate 98% 2,2,2-Trifluoroethyl p-toluenesulfonate 99% 2,2,2-Trifluoroethyl p-Toluenesulfonate 2,2,2-TRIFLUOROETHYL P-TOLUENESULFOTE 2,2,2-TRIFLUOROETHYL TOSYLATE 2,2,2-TRIFLUOROETHYL P-TOLUENESULPHONATE 2,2,2-TRIFLUOROETHYL-4-TOLUENESULFONATE 2,2,2-TRIFLUOROETHYL 4-TOLUENESULPHONATE 2,2,2-TRIFLUOROETHYL P-TOLUENESULF 2,2,2-trifluoro-ethano4-methylbenzenesulfonate Ethanol, 2,2,2-trifluoro-, p-toluenesulfonate 2,2,2-Trifluoroethyl p-toluenesulfonate, 98+% 2,2,2-Trifluoroethyl 4-toluenesulphonate 98% 2,2,2-Trifluoroethyl4-toluenesulphonate98% p-Toluenesulphonic acid 2,2,2-trifluoroethyl ester 4-Toluenesulfonic acid 2,2,2,-trifluoroethyl ester Trifluoroethyltosylate 4-Methylbenzenesulfonic acid 2,2,2-trifluoroethyl ester p-Methylbenzenesulfonic acid 2,2,2-trifluoromethyl 2. 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE 2,2,2-trifluoroethyl 4-methylbenzene-1-sulfonate 100532 2,2,2-Trifluoro-1-(4-methylbenzenesulfonate)-ethanol Ethanol, 2,2,2-trifluoro-, 1-(4-methylbenzenesulfonate) Trifluoroethyl p-toluene sulfonate 2,2,2-TRIFLUOROETHYL P-TO 2,2,2-Trifluoroethyl p-toluenesulfonate CasNo.433-06-7 2,2,2-Trifluoroethyl toluene-4-sulphonate 2,2,2-trifluoroethyl paramethylbenzenesulfonylacidester Azithromycin Impurity 74 2,2,2-trifluoroethyl ester 2,2,2-TRIFLUOROETHYL 4-METHYLBENZENESULFONATE 2,2,2-Trifluoroethyl p-toluenesulfonate 433-06-7 43-06-7 C9H9F3O3S CH3C6H4SO3CH2CF3 Fluorinated Building Blocks Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds Organic Building Blocks Sulfur Compounds Tosylates Building Blocks Fluorinated Building Blocks Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds Synthetic Organic Chemistry Organic Building Blocks Sulfur Compounds Tosylates API intermediates blocks BuildingBlocks