Fmoc-D-phenylalanine
- CAS No.
- 86123-10-6
- Chemical Name:
- Fmoc-D-phenylalanine
- Synonyms
- FMOC-D-PHE-OH;FMOC-D-PHE;(((9H-fluoren-9-yl)methoxy)carbonyl)-D-phenylalanine;FMOC-D-Phenylalanine-OH;N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-D-PHENYLALANINE;FmocAV21690;Fmoc-D-Phc-OH;Fmoc-D-phenyL;Fmoc-D-Phe-OH 98%;D-Fmoc-Phenylalanine
- CBNumber:
- CB3765825
- Molecular Formula:
- C24H21NO4
- Molecular Weight:
- 387.43
- MDL Number:
- MFCD00062955
- MOL File:
- 86123-10-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 181-185°C |
|---|---|
| Boiling point | 620.1±50.0 °C(Predicted) |
| Density | 1.276±0.06 g/cm3(Predicted) |
| refractive index | 38 ° (C=1, DMF) |
| storage temp. | 2-8°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder or Crystalline Powder |
| pka | 3.77±0.10(Predicted) |
| color | White |
| optical activity | 39°(C=0.01 g/mI, DMF, 20°C, 589nm) |
| BRN | 4767931 |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)/t22-/m1/s1 |
| InChIKey | SJVFAHZPLIXNDH-JOCHJYFZSA-N |
| SMILES | C(O)(=O)[C@@H](CC1=CC=CC=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
| CAS DataBase Reference | 86123-10-6(CAS DataBase Reference) |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| HS Code | 29242990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
Fmoc-D-phenylalanine price More Price(97)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.52148 | Fmoc-D-Phe-OH Novabiochem? | 86123-10-6 | 5G | $94.6 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.52148 | Fmoc-D-Phe-OH Novabiochem? | 86123-10-6 | 25g | $353 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.52148 | Fmoc-D-Phe-OH Novabiochem® | 86123-10-6 | 100 g | $1080 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.52148 | Fmoc-D-Phe-OH Novabiochem® | 86123-10-6 | 1 kg | $5880 | 2026-04-30 | Buy |
| Sigma-Aldrich | 47378 | Fmoc-D-Phe-OH ≥98.0% | 86123-10-6 | 5g | $111 | 2026-04-30 | Buy |
Fmoc-D-phenylalanine Chemical Properties, Uses, Production
Synthesis
The conventional synthetic method for 3-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one begins with 2-amino-3-benzyloxypyridine. A one-step condensation reaction with phosphine oxychloride yields the target product with a benzyl-protected hydroxyl group. The benzyl group is then removed under palladium-carbon hydrogenation to obtain 3-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. It is worth noting that a hydrogen pressure of one atmosphere is sufficient for the palladium-carbon hydrogenation process, and heating conditions can yield better reaction results.
Chemical Properties
White powder
Uses
N-Fmoc-D-phenylalanine is an N-Fmoc-protected form of D-Phenylalanine (P319410). D-Phenylalanine is an essential amino acid that serves as a primary precursor for the biosynthesis of catecholamines in the body. D-Phenylalanine is also known to antagonize stress-induced analgesia in humans, and also acts as an anti-enkephalinase agent.
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
Fmoc-D-phenylalanine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong fen Boyu Biotechnology Co.,LTD | 13356310019 13356310019; | boyu2024@163.com | China | 3947 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Latest Price from Fmoc-D-phenylalanine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-16 | Fmoc-D-Phe-OH
86123-10-6
|
1kg | 98% | 1T | Sichuan HongRi Pharma-Tech Co.,Ltd |
-
- Fmoc-D-Phe-OH
86123-10-6
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
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