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N-Fmoc-N'-trityl-D-histidine

N-Fmoc-N'-trityl-D-histidine Structure
N-Fmoc-N'-trityl-D-histidine structure
CAS No.
135610-90-1
Chemical Name:
N-Fmoc-N'-trityl-D-histidine
Synonyms
FMOC-D-HIS(TRT)-OH;FMOC-D-HIS(TRT);-D-histidine;-trityl-D-histidine;FMOC-D-HIS(1-TRT)-OH;FMOC-D-HIS(T-TRT)-OH;Histidine Impurity 70;Fmoc-D-His(tau-Trt)-OH;FMOC-D-HISTIDINE(TRITYL);Fmoc-D-His(1-Trt)-OH 98%
CBNumber:
CB4165075
Molecular Formula:
C40H33N3O4
Molecular Weight:
619.71
MDL Number:
MFCD00077061
MOL File:
135610-90-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:42:02
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N-Fmoc-N'-trityl-D-histidine Properties

Melting point 141-146°C
Boiling point 811.7±65.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 3.06±0.10(Predicted)
form powder to crystal
color White to Light yellow
optical activity [α]22/D -85.0°, c = 1% in chloroform
Major Application peptide synthesis
InChIKey XXMYDXUIZKNHDT-DIPNUNPCSA-N
SMILES C(O)(=O)[C@@H](CC1N=CN(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C=1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference 135610-90-1(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)
GHS02
Signal word  Warning
Hazard statements  H413
Precautionary statements  P273-P501
WGK Germany  3
HS Code  2933 29 90
Storage Class 11 - Combustible Solids
Hazard Classifications Aquatic Chronic 4
NFPA 704
1
0 0

N-Fmoc-N'-trityl-D-histidine price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.52161 Fmoc-D-His(Trt)-OH Novabiochem? 135610-90-1 5G $280 2026-04-30 Buy
Sigma-Aldrich 8.52161 Fmoc-D-His(Trt)-OH Novabiochem® 135610-90-1 1 kg $11040 2026-04-30 Buy
Sigma-Aldrich 772046 Fmoc-D-His(Trt)-OH 97% (HPLC) 135610-90-1 1g $113 2026-04-30 Buy
Sigma-Aldrich 772046 Fmoc-D-His(Trt)-OH 97% (HPLC) 135610-90-1 5g $145 2026-04-30 Buy
Sigma-Aldrich 8.52161 Fmoc-D-His(Trt)-OH Novabiochem® 135610-90-1 25 g $430 2025-07-31 Buy
Product number Packaging Price Buy
8.52161 5G $280 Buy
8.52161 1 kg $11040 Buy
772046 1g $113 Buy
772046 5g $145 Buy
8.52161 25 g $430 Buy

N-Fmoc-N'-trityl-D-histidine Chemical Properties, Uses, Production

Preparation

D-histidine is difficult to extract in large quantities from natural products, and is often prepared by configurational conversion of L-histidine. L-histidine undergoes an asymmetric conversion reaction catalyzed by salicylaldehyde using (R)-tartaric acid as a resolving agent and acetic acid as a solvent to yield D-histidine·(R)-tartrate (yield 98.69%, optical purity 98.26%). The process conditions are: reactant molar ratio: L-histidine:(R)-tartaric acid:salicylaldehyde = 1:1:0.05, reaction temperature 90℃, and reaction time 4 h. D-histidine·(R)-tartrate is then treated in methanol with 2 mol/L triethylamine to obtain D-histidine, with a yield of 94.06% and optical purity of 98.70%. The overall yield of D-histidine is 92.87%. The target compound N-Fmoc-N'-trityl-D-histidine is then prepared by Fmoc protection and Grignard reagent.

Chemical Properties

White powder

Uses

Fmoc-D-His(Trt)-OH, is an amino acid derivative used in chemical synthesis and peptide chemistry.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

N-Fmoc-N'-trityl-D-histidine Preparation Products And Raw materials

Raw materials

Preparation Products

N-Fmoc-N'-trityl-D-histidine Suppliers

Global Suppliers ( 256)
Supplier Tel Email Country ProdList Advantage
Sichuan Ampebiochem Co., Ltd. 028-65294243 18682730901 sales@ampebiochem.com China 1000 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Supplier Advantage
Sichuan Ampebiochem Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
GL Biochem (Shanghai) Ltd 64
Capot Chemical Co., Ltd 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky (shanghai) International Co.,Ltd 60
Syntechem Co.,Ltd 57

View Latest Price from N-Fmoc-N'-trityl-D-histidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Fmoc-N'-trityl-D-histidine pictures 2026-06-30 N-Fmoc-N'-trityl-D-histidine
135610-90-1
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
N-Fmoc-N'-trityl-D-histidine pictures 2019-07-06 N-Fmoc-N'-trityl-D-histidine
135610-90-1
 $1.00 1KG 99% 20kg Career Henan Chemical Co
N-Fmoc-N'-trityl-D-histidine pictures 2019-07-06 N-Fmoc-N'-trityl-D-histidine
135610-90-1
 $1.00 1KG 99% 20kg Career Henan Chemical Co

N-Fmoc-N'-trityl-D-histidine Spectrum

N-Fmoc-N'-trityl-D-histidine(135610-90-1)1HNMR

135610-90-1 (N-Fmoc-N'-trityl-D-histidine) Related Search:

Diethylstilbestrol L-Histidine 9-Fluorenylmethyl chloroformate Trityl Irbesartan Trityl candesartan cilexetil
L-Fmoc-Aspartic acid alpha-tert-butyl ester Nalpha-Fmoc-Ndelta-trityl-L-glutamine Triphenylmethyl Chloride Fmoc-His(Trt)-OH N-Fmoc-N'-tosyl-L-arginine
Fmoc-Asp(OtBu)-OH Fmoc-Lys(Boc)-OH Trityl candesartan Fmoc-Phe-OH Fmoc-OSu
Fmoc-Lys(Dnp)-OH Methoxycarbonylsulfenyl chloride N-Fmoc-S-trityl-D-cysteine

1of4

FMOC-N-IM-TRITYL-D-HISTIDINE FMOC-D-HIS(1-TRT)-OH FMOC-D-HISTIDINE(1-TRT)-OH FMOC-D-HISTIDINE(TRITYL) FMOC-D-HIS(T-TRT)-OH N-ALPHA-FMOC-N-IM-TRITYL-D-HISTIDINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-IM-TRITYL-D-HISTIDINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-TAU-TRITYL D-HISTIDINE N-α-Fmoc-N-im-trityl-D-histidine NALPHA-9-Fluorenylmethoxycarbonyl-Nim-trityl-D-histidine N-Fmoc-N'-trityl-D-histidine Fmoc-D-His(tau-Trt)-OH FMoc-D-His(Trt)-OH N-α-FMoc-N-iM-trityl-D-histidine (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoic acid (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-tritylimidazol-4-yl)propanoic acid -trityl-D-histidine 2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-[1-(triphenylmethyl)-4-imidazolyl]propanoic acid N-FMoc-1-trityl-D-histidine, 98% (R)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(1-trityl-1H-iMidazol-4-yl)propanoic acid Nα-Fmoc-Nim-trityl-D-histidine≥ 99.5% (HPLC, Chiral purity) Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-τ-(triphenylmethyl)-D-histidine (9H-Fluoren-9-yl)MethOxy]Carbonyl D-His(Trt)-OH Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-tele-(triphenylmethyl)-D-histidine Fmoc-D-His(Trt)-OH 97% (HPLC) D-Histidine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-1-(triphenylmethyl)- N-Fmoc-1-trityl-D-histidine,98% -D-histidine Nalpha-Fmoc-tele-trityl-D-histidine N-Fmoc-N'-trityl-D-histidine USP/EP/BP Nα-Fmoc-Nim-trityl-D-histidine N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-(triphenylmethyl)-D-histidine N-Fmoc-N'-triphenylmethyl-D-histidine Fmoc-D-His(Trt)-OH Fmoc-D-His(1-Trt)-OH 98% FMOC-D-HIS(TRT) FMOC-D-HIS(TRT)-OH Histidine Impurity 70 135610-90-1 135670-90-1 Fmoc-Amino Acids and Derivatives Fmoc-Amino acid series Amino Acids