3-Bromothiophene-2-carbaldehyde
- CAS No.
- 930-96-1
- Chemical Name:
- 3-Bromothiophene-2-carbaldehyde
- Synonyms
- 3-BROMOTHIOPHENE-2-CARBOXALDEHYDE;THCHO-Br;BUTTPARK 43\57-52;3-Bromothiophene-2;3-Bromo-2-Formylthophene;3-BROMO-2-FORMYLTHIOPHENE;3-BROMO-2-THIOPHENECARBALDEHYDE;3-BROMOTHIOPHENE-2-CARBALDEHYDE;3-bromothiophene-2-formaldehyde;3-Bromo-2-thiophenecarboxaldehyde
- CBNumber:
- CB4290245
- Molecular Formula:
- C5H3BrOS
- Molecular Weight:
- 191.05
- MDL Number:
- MFCD00126680
- MOL File:
- 930-96-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 25 °C |
|---|---|
| Boiling point | 77-79°C 0,2mm |
| Density | 1.755 g/mL at 25 °C |
| refractive index | 1.6377 |
| Flash point | 110-113°C/10mm |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| form | clear liquid |
| color | Light yellow to Amber to Dark green |
| Water Solubility | Not miscible in water. |
| Sensitive | Air Sensitive |
| BRN | 109757 |
| InChI | InChI=1S/C5H3BrOS/c6-4-1-2-8-5(4)3-7/h1-3H |
| InChIKey | BCZHCWCOQDRYGS-UHFFFAOYSA-N |
| SMILES | C1(C=O)SC=CC=1Br |
| CAS DataBase Reference | 930-96-1(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P280a-P305+P351+P338-P321-P332+P313-P337+P313-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/38-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36/37/39-22-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
3-Bromothiophene-2-carbaldehyde price More Price(109)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 716553 | 3-Bromothiophene-2-carboxaldehyde 96% | 930-96-1 | 1g | $41.9 | 2026-04-30 | Buy |
| TCI Chemical | B2934 | 3-Bromothiophene-2-carboxaldehyde >95.0%(GC) | 930-96-1 | 1g | $29 | 2026-04-30 | Buy |
| TCI Chemical | B2934 | 3-Bromothiophene-2-carboxaldehyde >95.0%(GC) | 930-96-1 | 5g | $98 | 2026-04-30 | Buy |
| Usbiological | 261701 | 3-Bromothiophene-2-carbaldehyde Asreported | 930-96-1 | 1g | $315 | 2026-06-03 | Buy |
| Usbiological | 261701 | 3-Bromothiophene-2-carbaldehyde Asreported | 930-96-1 | 2g | $430 | 2026-06-03 | Buy |
3-Bromothiophene-2-carbaldehyde Chemical Properties,Uses,Production
Chemical Properties
Colorless to yellow liquid
Uses
3-Bromothiophene-2-carboxaldehyde is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 34, p. 1805, 1991 DOI: 10.1021/jm00110a008
Synthesis
872-31-1
68-12-2
930-96-1
Diisopropylamine (51.6 kg, 509.9 mol, 1.0 eq.) and anhydrous tetrahydrofuran (THF) (385.0 kg) were added to a 1000 L autoclave under nitrogen protection. After cooling the system to 0-5 °C, n-butyllithium (BuLi) (131.4 kg, 463.8 mol, 1.0 eq.) was slowly added. After addition, stirring was continued at 0-5 °C for 30 min. Subsequently, a solution of 3-bromothiophene (75.0 kg, 460.0 mol, 1.0 eq.) in THF (20.0 kg) was added dropwise. After dropwise addition, stirring was continued at 0-5 °C for 30 min. Next, a solution of N,N-dimethylformamide (DMF) (35.3 kg, 473.3 mol, 1.0 eq.) in THF (10.0 kg) was slowly added dropwise. After completion of dropwise addition, stirring was maintained at 0-5 °C for 3 hours. Upon completion of the reaction, a 14% aqueous ammonium chloride (NH4Cl) solution (700.0 g) was slowly added dropwise at 0-5 °C. After addition, the reaction was stirred at 0-5 °C for 15 min and allowed to stand for 15 min. The organic phase was separated and stored temporarily in a clean PTFE drum. The aqueous phase was re-pumped into the reactor, methyl tertiary butyl ether (MTBE) (150.0 kg) was added, stirred for 15 min, and allowed to stand for 15 min before separating the phase and collecting the upper organic phase. All organic phases were combined and dried with anhydrous sodium sulfate (85.0 kg) for several hours until the moisture content was <1%. Filtration, the filter cake was washed with methyl tert-butyl ether (20 mL x 2), the filtrates were combined and concentrated under reduced pressure to remove the solvent to give 3-bromothiophene-2-carbaldehyde (93.8 kg, 100% yield).
References
[1] Patent: CN103172646, 2016, B. Location in patent: Paragraph 0101-0104
[2] European Journal of Organic Chemistry, 2016, vol. 2016, # 31, p. 5263 - 5273
[3] Macromolecules, 2013, vol. 46, # 6, p. 2078 - 2091
[4] Tetrahedron Letters, 2012, vol. 53, # 2, p. 166 - 169
[5] Journal of the American Chemical Society, 2014, vol. 136, # 19, p. 7132 - 7139
3-Bromothiophene-2-carbaldehyde Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Habo Medical Technology Co., Ltd. | 13376080562 13376090521 | sales@habotech.com | China | 726 | 60 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Beijing Donghualituo Techonlogy Development Co.,Ltd. | 010-88425576 | sales@dhltchem.com | China | 793 | 59 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Lastest Price from 3-Bromothiophene-2-carbaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 3-Bromo-2-thiophenecarbaldehyde
930-96-1
|
$1.00-200.00 | 1KG | 99%, 99.5% Sublimated | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-20 | 3-Bromothiophene-2-carbaldehyde
930-96-1
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2025-04-04 | 3-Bromothiophene-2-carbaldehyde
930-96-1
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 3-Bromo-2-thiophenecarbaldehyde
930-96-1
- $1.00-200.00
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-
- 3-Bromothiophene-2-carbaldehyde
930-96-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Bromothiophene-2-carbaldehyde
930-96-1
- 98%
- Henan Aochuang Chemical Co.,Ltd.
