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Diethyl butylmalonate

Diethyl butylmalonate structure

CAS No.: 133-08-4

Chemical Name:: Diethyl butylmalonate

Synonyms: Diethyl 2-butylmalonate;BMDE;BUTYLMALONIC ESTER;ETHYL BUTYLMALONATE;DIETHYL BUTYLMALONATE;LABOTEST-BB LTBB001318;DIETHYL N-BUTYLMALONATE;DiethylButylmalonate>Diethyl butyl malmalate;N-BUTYL DIETHYL MALONATE

CBNumber:: CB4335342

Molecular Formula:: C11H20O4

Molecular Weight:: 216.27

MDL Number:: MFCD00009170

MOL File:: 133-08-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:21:59

Product description	Number	Pack Size	Price
Diethyl butylmalonate 99%	112038	100ml	$52.4
Diethyl Butylmalonate >99.0%(GC)	B0381	25mL	$19
Diethyl Butylmalonate >99.0%(GC)	B0381	500mL	$92
Diethyl 2-n-Butylmalonate	TRC-D443880-50G	50g	$209
Diethyl 2-n-Butylmalonate	TRC-D443880-1G	1g	$97
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Diethyl butylmalonate Properties

Melting point	238 °C
Boiling point	235-240 °C (lit.)
Density	0.983 g/mL at 25 °C (lit.)
vapor pressure	1Pa at 20℃
refractive index	n20/D 1.422(lit.)
Flash point	201 °F
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO : 100 mg/mL (462.38 mM; Need ultrasonic)\|
pka	13.47±0.46(Predicted)
form	clear liquid
color	Colorless to Almost colorless
Specific Gravity	0.975 (20/4℃)
Water Solubility	330mg/L at 20℃
Merck	14,1576
BRN	608785
InChI	1S/C11H20O4/c1-4-7-8-9(10(12)14-5-2)11(13)15-6-3/h9H,4-8H2,1-3H3
InChIKey	RPNFNBGRHCUORR-UHFFFAOYSA-N
SMILES	CCCCC(C(=O)OCC)C(=O)OCC
LogP	3.4 at 23℃
CAS DataBase Reference	133-08-4(CAS DataBase Reference)
FDA UNII	CYY2Q744WB
NIST Chemistry Reference	Diethyl butylmalonate(133-08-4)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H227

Precautionary statements

P210e-P280a-P370+P378a-P403+P235-P501a

PPE

Eyeshields, Gloves

Safety Statements

24/25

WGK Germany

HS Code

29171990

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2

REACH Registrations

Active

NFPA 704

	2
1		0

Diethyl butylmalonate price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	112038	Diethyl butylmalonate 99%	133-08-4	100ml	$52.4	2026-04-30	Buy
TCI Chemical	B0381	Diethyl Butylmalonate >99.0%(GC)	133-08-4	25mL	$19	2026-04-30	Buy
TCI Chemical	B0381	Diethyl Butylmalonate >99.0%(GC)	133-08-4	500mL	$92	2026-04-30	Buy
TRC	TRC-D443880-50G	Diethyl 2-n-Butylmalonate	133-08-4	50g	$209	2026-06-03	Buy
TRC	TRC-D443880-1G	Diethyl 2-n-Butylmalonate	133-08-4	1g	$97	2026-06-03	Buy

Product number	Packaging	Price	Buy
112038	100ml	$52.4	Buy
B0381	25mL	$19	Buy
B0381	500mL	$92	Buy
TRC-D443880-50G	50g	$209	Buy
TRC-D443880-1G	1g	$97	Buy

Diethyl butylmalonate Chemical Properties,Uses,Production

Synthesis

Diethyl malonate is mixed with sodium ethoxide, and then chlorobutane is added to form the reaction. The crude product is separated and recovered ethanol, washed and dehydrated to obtain Diethyl butylmalonate.

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

Diethyl butylmalonate is used as a reagent in the synthesis of 2,5-dihydropyrrole formyl hydroxyamino derivatives as peptide deformylase inhibitors against drug-resistant bacteria.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 1, p. 250, 1941
The Journal of Organic Chemistry, 44, p. 3492, 1979 DOI: 10.1021/jo01334a009

General Description

Diethyl malonate (DEM) undergoes alkylation by ethyliodide, which is used to study the phase transfer catalysis (PTC) technique.

Flammability and Explosibility

Not classified

Diethyl butylmalonate synthesis

Synthesis of Diethyl butylmalonate from Butylamine and Diethyl malonate

Diethyl butylmalonate Preparation Products And Raw materials

Raw materials

1-Chlorobutane Sodium ethoxide Diethyl malonate Malonic acid Propanedioic acid,2-butyl-2-(2-propen-1-yl)-, 1,3-diethyl ester

Propanedioic acid,2-butylidene-, 1,3-diethyl ester diethyl methylidenemalonate 1-Butanol Diethyl oxalate Butylamine

Ethyl Hexanoate 1-Bromobutane

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Preparation Products

Phenylbutazone BUTYL TRIETHYL MALONATE MOFEBUTAZONE Diethyl dibutylmalonate

Diethyl butylmalonate Suppliers

Global( 267)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Junwee Chemical co., Ltd.	+86-571-85808636 +86-13958122542	sales@junweechem.com	China	823	58
Hebei Fengjia New Material Co., Ltd	+86-0311-87836622 +86-18712993135	sales01@tairunfaz.com	China	8046	58
Hebei Chuanghai Biotechnology Co., Ltd	+86-17732866630	mina@chuanghaibio.com	China	18114	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7240	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21531	55
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5898	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9631	58
Zhengzhou Alfa Chemical Co.,Ltd	+86-18530059196	sale04@alfachem.cn	China	9609	58
Hebei Yanxi Chemical Co., Ltd.	+86-17531190177	faithe@yan-xi.com	China	5838	58

Supplier	Advantage
Junwee Chemical co., Ltd.	58
Hebei Fengjia New Material Co., Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shandong chuangyingchemical Co., Ltd.	58
career henan chemical co	58
Antai Fine Chemical Technology Co.,Limited	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58

View Lastest Price from Diethyl butylmalonate manufacturers

Update time	Product	Min. Order	Purity	Supply Ability	Manufacturer
2025-06-27	Diethyl butylmalonate 133-08-4	1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd
2025-06-20	Diethyl butylmalonate 133-08-4	1kg	0.99	100tons	Hebei Yanxi Chemical Co., Ltd.
2025-06-20	Diethyl butylmalonate 133-08-4	1kg	0.99	100tons	Hebei Yanxi Chemical Co., Ltd.

Diethyl butylmalonate
133-08-4
99%
Hebei Chuanghai Biotechnology Co., Ltd

Diethyl butylmalonate
133-08-4
0.99
Hebei Yanxi Chemical Co., Ltd.

Diethyl butylmalonate
133-08-4
0.99
Hebei Yanxi Chemical Co., Ltd.

Diethyl butylmalonate Spectrum

Diethyl butylmalonate(133-08-4)MS Diethyl butylmalonate(133-08-4)¹HNMR Diethyl butylmalonate(133-08-4)¹³CNMR Diethyl butylmalonate(133-08-4)IR1 Diethyl butylmalonate(133-08-4)Raman

133-08-4(Diethyl butylmalonate)Related Search:

DIETHYL DIETHYLMALONATE Ethylene glycol diethyl ether Diisopropyl malonate Mefenpyr-diethyl Diethyl methylmalonate

Diethyl isopropylmalonate Diethyl bis(hydroxymethyl)malonate Diethyl benzylmalonate Ethyl malonyl chloride Diethyl allylmalonate

Diethyl dipropylmalonate 2-AMINODIETHYLMALONATE Diethyl phenylmalonate DIETHYL DIMETHYLMALONATE Diethyl ketomalonate

Diethyl oxalate Diethyl malonate N-(n-butyl)thiophosphoric triamide

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BMDE BUTYLMALONIC ACID DIETHYL ESTER ETHYL BUTYLMALONATE DIETHYL N-BUTYLMALONATE DIETHYL BUTYLMALONATE LABOTEST-BB LTBB001318 N-BUTYL DIETHYL MALONATE N-BUTYLMALONIC ACID DIETHYL ESTER N-BUTYMALONIC ACID DIETHYL ESTER 2-butyl-malonicaciddiethylester butyl-propanedioicaciddiethylester Diethyl normal-butylmalonate Malonic acid, butyl-, diethyl ester Propanedioic acid, butyl-, diethyl ester Propanedioicacid,butyl-,diethylester n-Butylammonic acid diethyl ester BUTYLMALONIC ESTER n-Butylmalonsurediethylester Diethyl 2-butylpropanedioate Diethyl n-butylmalonate,99% DIETHYL BUTYLMALONATE FOR SYNTHESIS Propanedioic acid,2-butyl-, 1,3-diethyl ester Diethyl butylMalonate 99% DiethylButylmalonate> 133-08-4 Diethyl butylmalonate C11H20O4 Diethyl butyl malmalate 1,3-Diethyl 2-butylpropanedioate Diethyl 2-butylmalonate 133-08-4 C11H20O4 CH3CH23CHCO2C2H52 Esters Organic Building Blocks Building Blocks C10 to C11 Carbonyl Compounds TheMalonateRamificationProducts Pharmaceutical Intermediates C10 to C11 Carbonyl Compounds Esters