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2-Mercaptonicotinic acid

2-Mercaptonicotinic acid structure

CAS No.: 38521-46-9

Chemical Name:: 2-Mercaptonicotinic acid

Synonyms: 2-sulfanylpyridine-3-carboxylic acid;2-Mercaptonicotinic;2-MERCAPTOPYRIDINE-3-CARBOXYLIC ACID;TIMTEC-BB SBB000123;2-THIONICOTINIC ACID;Mercaptonicotinicaci;LABOTEST-BB LT01596005;2-MERCAPTOCOTINIC ACID;2-mercaptonitinic acid;2-Mercaptonicotinicaci

CBNumber:: CB4378840

Molecular Formula:: C6H5NO2S

Molecular Weight:: 155.17

MDL Number:: MFCD00010102

MOL File:: 38521-46-9.mol

MSDS File:: SDS

Last updated:2026-05-28 01:47:28

Product description	Number	Pack Size	Price
2-Mercaptopyridine-3-carboxylic acid technical grade	419702	25g	$72.8
2-Mercaptopyridine-3-carboxylic acid technical grade	419702	100g	$192
2-Mercaptonicotinic Acid	M1213	25g	$51
2-Mercaptonicotinic acid	FM00951	0.25kg	$900
2-Mercaptonicotinic acid	FM00951	0.1kg	$900
More product size

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2-Mercaptonicotinic acid Properties

Melting point	263-265 °C(lit.)
Boiling point	295.3±50.0 °C(Predicted)
Density	1.357 (estimate)
refractive index	1.5380 (estimate)
storage temp.	Inert atmosphere,Room Temperature
pka	1.98±0.20(Predicted)
form	crystalline (fine)
color	yellow
Sensitive	Air Sensitive
BRN	119029
InChI	InChI=1S/C6H5NO2S/c8-6(9)4-2-1-3-7-5(4)10/h1-3H,(H,7,10)(H,8,9)
InChIKey	WYKHFQKONWMWQM-UHFFFAOYSA-N
SMILES	C1(=S)NC=CC=C1C(O)=O
CAS DataBase Reference	38521-46-9(CAS DataBase Reference)
FDA UNII	EU7D859ABZ
EPA Substance Registry System	2-Mercaptonicotinic acid (38521-46-9)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-37/39

WGK Germany

10-23

TSCA

TSCA listed

HazardClass

IRRITANT

HS Code

29309090

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
2		0

2-Mercaptonicotinic acid price More Price(88)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	419702	2-Mercaptopyridine-3-carboxylic acid technical grade	38521-46-9	25g	$72.8	2026-04-30	Buy
Sigma-Aldrich	419702	2-Mercaptopyridine-3-carboxylic acid technical grade	38521-46-9	100g	$192	2026-04-30	Buy
TCI Chemical	M1213	2-Mercaptonicotinic Acid	38521-46-9	25g	$51	2026-04-30	Buy
Biosynth	FM00951	2-Mercaptonicotinic acid	38521-46-9	0.25kg	$900	2026-06-04	Buy
Biosynth	FM00951	2-Mercaptonicotinic acid	38521-46-9	0.1kg	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
419702	25g	$72.8	Buy
419702	100g	$192	Buy
M1213	25g	$51	Buy
FM00951	0.25kg	$900	Buy
FM00951	0.1kg	$900	Buy

2-Mercaptonicotinic acid Chemical Properties,Uses,Production

Chemical Properties

yellow powder

Uses

2-Mercaptopyridine-3-carboxylic acid may be used for the synthesis of poly[[diaquabis([μ]2-4,4 ′-bipyridyl)iron(II)] bis{2-[(3-carboxypyridin-2-yl)disulfanyl]nicotinate}] and 2-(2-carboxyethylthio)nicotinic acid.

Reactions

2-Mercaptonicotinic acid is prone to decomposition and deterioration at high temperatures, it can undergo nucleophilic substitution reactions under the action of alkaline substances.

Hazard

2-Mercaptonicotinic acid is a flammable liquid and vapor, it causes severe skin burns and eye damage and may cause respiratory irritation.

Synthesis

2942-59-8

38521-46-9

The general procedure for the synthesis of 2-mercaptonicotinic acid from 2-chloronicotinic acid was as follows: a suspension of 2-chloronicotinic acid (790 mg, 5 mmol) and thiourea (457 mg, 6 mmol) was suspended in water (15 mL) and the reaction was carried out at reflux for 8 h at 90 °C. Upon completion of the reaction, the mixture was cooled to room temperature to obtain a pale yellow suspension. Subsequently, the pH was adjusted to about 8 with dilute hydrochloric acid and stirred for 10 minutes to precipitate 2-mercaptonicotinic acid as a pale yellow solid. The solid was separated by filtration and dried to give the target product 2-mercaptonicotinic acid (590 mg, 84% yield).

References

[1] Patent: CN103626693, 2016, B. Location in patent: Paragraph 0157-0159
[2] Roczniki Chemii, 1932, vol. 12, p. 493,495
[3] Chem. Zentralbl., 1932, vol. 103, # II, p. 3400
[4] Journal of the American Chemical Society, 1948, vol. 70, p. 3908,3910

2-Mercaptonicotinic acid Preparation Products And Raw materials

Raw materials

2-Chloronicotinic acid Thiourea

Preparation Products

2-(2-Thiopyridin-3-yl)-1H-benzimidazole methyl 1-methyl-2-thioxo-1,2-dihydropyridine-3-carboxylate 3-Pyridinecarboxylicacid,1,2-dihydro-2-thioxo-,hydrazide(9CI) 2,3-Dihydropyrano[2,3-b]pyridin-4(4H)-one

2-Mercaptonicotinic acid Suppliers

Global( 340)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shijiazhuang Dowell Chemical Co.,Ltd	+8618633820607	sell@dowechem.com	China	89	58
Shanghai UCHEM Inc.	+1-7027589231 +1-7027589231	sales@myuchem.com	China	8834	58
Apeloa production Co.,Limited	+8619933239880	admin@apcl.com.cn	China	861	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2950	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Shijiazhuang Dowell Chemical Co.,Ltd	58
Shanghai UCHEM Inc.	58
Apeloa production Co.,Limited	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 2-Mercaptonicotinic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-24	2-Mercaptonicotinic acid 38521-46-9	$10.00-50.00	10g	0.98	10kg	Paints customs n glass
2025-11-18	2-Mercaptonicotinic acid 38521-46-9	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2025-05-23	2-Mercaptonicotinic acid 38521-46-9	$10.00	1kg	99%	20 ton	Hebei Zhuanglai Chemical Trading Co Ltd

2-Mercaptonicotinic acid
38521-46-9
$10.00-50.00
0.98
Paints customs n glass

2-Mercaptonicotinic acid
38521-46-9
$1.10
99.00%
Dideu Industries Group Limited

2-Mercaptonicotinic acid
38521-46-9
$10.00
99%
Hebei Zhuanglai Chemical Trading Co Ltd

2-Mercaptonicotinic acid Spectrum

2-Mercaptonicotinic acid(38521-46-9)MS 2-Mercaptonicotinic acid(38521-46-9)¹HNMR 2-Mercaptonicotinic acid(38521-46-9)¹³CNMR 2-Mercaptonicotinic acid(38521-46-9)IR1 2-Mercaptonicotinic acid(38521-46-9)IR2 2-Mercaptonicotinic acid(38521-46-9)Raman

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2-MERCAPTONICOTINIC ACID 2-MERCAPTO-3-PYRIDINECARBOXYLIC ACID 2-SULFANYLNICOTINIC ACID 2-THIONICOTINIC ACID LABOTEST-BB LT01596005 TIMTEC-BB SBB000123 1,2-dihydro-2-thioxo-3-pyridinecarboxylicaci 2-Mercapto-3-pyridine carboxlic acid 2-MERCAPTONICOTINIC ACID, TECH. 2-MERCAPTONICOTINIC ACID, 98+% 2-SULFANYLIDENE-1H-PYRIDINE-3-CARBOXYLIC ACID 3-Pyridinecarboxylic acid, 1,2-dihydro-2-thioxo- 2-Mercaptonicotinic acid 98% 2-MERCAPTOCOTINIC ACID 1,2-dihydro-2-thioxo-3-pyridinecarboxylic acid 2-mercaptonitinic acid 2-MERCAPTONICOTINIC ACID (2-MERCAPTOPYRIDINE-3-CARBOXYLIC ACID) 2-Mercapto-3-carboxypyridine 3-Aza-2-thiosalicylic acid 2- Mercaptonictinic Acid 1,2-dihydro-2-thioxopyridine-3-carboxylic acid 2-Thionicotinic acid 98% 2-mercaptonicotinic acid(SALTDATA: FREE) 2-sulfanylpyridine-3-carboxylic acid 2-Mercaptonicotinic acid, 90+% 2-thioxo-1,2-dihydropyridine-3-carboxylic acid Mercaptonicotinicaci 2-Mercaptopyridine-3-carboxylic acid technical grade 2-thioxo-1H-pyridine-3-carboxylic acid 2-Mercaptonicotinic acid ISO 9001：2015 REACH 2-Mercaptonicotinicaci 2-MERCAPTOPYRIDINE-3-CARBOXYLIC ACID 2-Mercaptonicotinic 38521-46-9 C6H5NO2S C6HNO2S Heterocyclic Building Blocks Pyridines Building Blocks C6 Carboxylic Acids blocks Pyridines Carboxylic Acids Organic acids