2-chloro-5-cyanopyridine
- CAS No.
- 33252-28-7
- Chemical Name:
- 2-chloro-5-cyanopyridine
- Synonyms
- 6-CHLORONICOTINONITRILE;6-CHLOROPYRIDINE-3-CARBONITRILE;6-Chloronicotinitrile;BUTTPARK 37\12-46;oro-5-cyanopyridine;6-CHLORONICOTINONTRILE;6-chloronicotininitrile;6-Chloronicotinonitride;6-Chloro-3-cyanopyridin;2-CHLORO-5-CYANOPYRIDINE
- CBNumber:
- CB4366126
- Molecular Formula:
- C6H3ClN2
- Molecular Weight:
- 138.55
- MDL Number:
- MFCD00084941
- MOL File:
- 33252-28-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 116-120 °C(lit.) |
|---|---|
| Boiling point | 105-107°C 1mm |
| Density | 1.33±0.1 g/cm3(Predicted) |
| Flash point | 105-107°C/1mm |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Ethanol |
| pka | -3.56±0.10(Predicted) |
| form | powder to crystal |
| color | White to Light yellow to Light orange |
| BRN | 113867 |
| InChI | InChI=1S/C6H3ClN2/c7-6-2-1-5(3-8)4-9-6/h1-2,4H |
| InChIKey | ORIQLMBUPMABDV-UHFFFAOYSA-N |
| SMILES | C1=NC(Cl)=CC=C1C#N |
| CAS DataBase Reference | 33252-28-7(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,T,Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36-36/37/39-37 | |||||||||
| RIDADR | 3276 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Toxic | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-chloro-5-cyanopyridine price More Price(103)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 510734 | 6-Chloro-3-pyridinecarbonitrile 97% | 33252-28-7 | 5g | $49.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | 510734 | 6-Chloro-3-pyridinecarbonitrile 97% | 33252-28-7 | 25g | $169 | 2026-04-30 | Buy |
| TCI Chemical | C2056 | 2-Chloro-5-cyanopyridine >97.0%(GC)(N) | 33252-28-7 | 5g | $50 | 2026-04-30 | Buy |
| TCI Chemical | C2056 | 2-Chloro-5-cyanopyridine >97.0%(GC)(N) | 33252-28-7 | 25g | $197 | 2026-04-30 | Buy |
| Usbiological | 230158 | 2-Chloro-5-cyanopyridine ≥97% (HPLC) ≥97%(HPLC) | 33252-28-7 | 1g | $156 | 2026-06-03 | Buy |
2-chloro-5-cyanopyridine Chemical Properties,Uses,Production
Chemical Properties
Yellow to Brown Cryst
Uses
2-Chloro-5-cyanopyridine (cas# 33252-28-7) is a compound useful in organic synthesis.
Uses
6-Chloro-3-pyridinecarbonitrile (2-Chloro-5-cyanopyridine) may be used in the preparation of:
- (6-chloro-3-pyridyl)methylamine
- 2-(N-methyl-N-isopropylamino)-5-cyanopyridine
- S-(5-cyano-2-pyridyl)thiouronium chloride
General Description
6-Chloro-3-pyridinecarbonitrile is a substituted pyridine.
Synthesis
Taking 2-chloro-5-trichloromethylpyridine and ammonium chloride as raw materials, the weight ratio of 2-chloro-5-trichloromethylpyridine to ammonium chloride is 1:1.1 to 1:3, and under the catalyst's catalytic action, the reaction temperature is in the range of 100 to 250C, and the reaction time is in the range of 1 to 18 hours, to produce 2-chloro-5-cyanopyridine.
2-chloro-5-cyanopyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Jubai Biomedical Technology Co., Ltd. | 13585203734 | info@jbzml.com | China | 200 | 58 |
| Shanghai EachChem Co., Ltd. | 021-64196659 13564486206 | info@eachchem.com | China | 50 | 55 |
| Jiangsu Mingchem Corporation | 0519-85170101 | sales@mingchem.com | China | 632 | 55 |
| Lanzhou ZhuoKe biotechnology co., LTD. | 18919927361 | zhang999zhi@sina.com | China | 185 | 58 |
| Changzhou hanergy Biotechnology Co., Ltd | 13915872857 | hannengchemical@163.com | China | 117 | 58 |
| Zaozhuang Benefit Chemical Co., Ltd. | 0531-69958783 15508681609 | 1948129184@qq.com | China | 208 | 60 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
Related articles
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- Apr 16,2025
View Lastest Price from 2-chloro-5-cyanopyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-02 | (6-Chloro-3-pyridinyl)acetonitrile
33252-28-7
|
$1.00-200.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
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2023-10-22 | 2-chloro-5-cyanopyridine
33252-28-7
|
1drums | 99%min. | 10tons | Shanghai Xinchem Co., Ltd. | ||
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2022-01-04 | 2-Chloro-5-cyanopyridine
33252-28-7
|
1g | 98%min | 100kgs/month | Shanghai Rlavie Technology Co ltd |
-

- (6-Chloro-3-pyridinyl)acetonitrile
33252-28-7
- $1.00-200.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 2-chloro-5-cyanopyridine
33252-28-7
- 99%min.
- Shanghai Xinchem Co., Ltd.
-

- 2-Chloro-5-cyanopyridine
33252-28-7
- 98%min
- Shanghai Rlavie Technology Co ltd








