2-Bromo-7-hydroxynaphthalene
- CAS No.
- 116230-30-9
- Chemical Name:
- 2-Bromo-7-hydroxynaphthalene
- Synonyms
- 7-BROMONAPHTHALEN-2-OL;7-Bromo-2-naphthol;7-Bromo-2-Naphthalenol;BroMonaphthalen-2-ol;Naproxen Impurity 28;7-Bromo-2-naphthol 99%;7-Bromo-2-naphthol >7-Bromonaphthalene-2-ol;2-Naphthalenol,7-broMo-;7-Bromo-2-naphthol, >=98%
- CBNumber:
- CB4432461
- Molecular Formula:
- C10H7BrO
- Molecular Weight:
- 223.07
- MDL Number:
- MFCD00277644
- MOL File:
- 116230-30-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 7-Bromo-2-naphthol 99% | 690244 | 1g | $86 |
| 7-Bromo-2-naphthol 99% | 690244 | 5g | $409 |
| 7-Bromo-2-naphthol >97.0%(GC) | B4580 | 1g | $39 |
| 7-Bromo-2-naphthol >97.0%(GC) | B4580 | 5g | $144 |
| 7-Bromonaphthalen-2-ol ≥95% | OR301112 | 1g | $21 |
| More product size | |||
| Melting point | 133-138 °C |
|---|---|
| Boiling point | 353.8±15.0 °C(Predicted) |
| Density | 1.614±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 9.17±0.40(Predicted) |
| form | powder to crystal |
| color | White to Light yellow |
| InChI | InChI=1S/C10H7BrO/c11-9-3-1-7-2-4-10(12)6-8(7)5-9/h1-6,12H |
| InChIKey | VWSBGGRCEQOTNU-UHFFFAOYSA-N |
| SMILES | C1=C2C(C=CC(Br)=C2)=CC=C1O |
| CAS DataBase Reference | 116230-30-9 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H318-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 37/38-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29081990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Bromo-7-hydroxynaphthalene price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 690244 | 7-Bromo-2-naphthol 99% | 116230-30-9 | 1g | $86 | 2023-06-20 | Buy |
| Sigma-Aldrich | 690244 | 7-Bromo-2-naphthol 99% | 116230-30-9 | 5g | $409 | 2023-06-20 | Buy |
| TCI Chemical | B4580 | 7-Bromo-2-naphthol >97.0%(GC) | 116230-30-9 | 1g | $39 | 2026-04-30 | Buy |
| TCI Chemical | B4580 | 7-Bromo-2-naphthol >97.0%(GC) | 116230-30-9 | 5g | $144 | 2026-04-30 | Buy |
| Apolloscientific | OR301112 | 7-Bromonaphthalen-2-ol ≥95% | 116230-30-9 | 1g | $21 | 2026-06-04 | Buy |
2-Bromo-7-hydroxynaphthalene Chemical Properties,Uses,Production
Uses
2-Bromo-7-hydroxynaphthalene is used as an intermediate in organic synthesis and pharmaceuticals.
Chemical Properties
White powder
Synthesis
582-17-2
116230-30-9
The general procedure for the synthesis of 7-bromo-2-naphthol from 2,7-dihydroxynaphthalene was as follows: 1. Preparation of 2-bromo-7-methoxynaphthalene: Triphenylphosphine (89.7 g, 0.342 mol) and acetonitrile (350 mL) were added to a 1 L flask under nitrogen protection and the mixture was cooled to 10 °C. Bromine (17.6 mL, 0.342 mol) was added slowly and dropwise over 10 min. After removing the cooling bath, 2,7-dihydroxynaphthalene (50.0 g, 0.312 mol) was added and rinsed with 350 mL of acetonitrile. The resulting yellow-brown mixture was heated to reflux for 3 hours. Subsequently, the acetonitrile was removed by distillation under reduced pressure, taking about 2 hours to give an off-white solid. 2. Preparation of 7-bromo-2-naphthol: The above solid was heated to 280°C within 30 minutes to form a black liquid. The liquid was continued to be heated to 310°C within 20 minutes and maintained at this temperature for 15 minutes until gas release ceased. After the black mixture was cooled to room temperature, 34.5 g of the intermediate title compound was obtained by chromatographic separation as an off-white solid with HPLC purity of 87% (43% yield).
References
[1] Journal of the American Chemical Society, 2008, vol. 130, # 13, p. 4541 - 4552
[2] Dyes and Pigments, 2014, vol. 107, p. 174 - 181
[3] Patent: WO2015/121785, 2015, A1. Location in patent: Page/Page column 32; 33
[4] Helvetica Chimica Acta, 1999, vol. 82, # 7, p. 981 - 1004
[5] Chemical Communications, 2012, vol. 48, # 5, p. 750 - 752
2-Bromo-7-hydroxynaphthalene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CD Chemical Group Limited | +86-13651442114 | info@codchem.com | China | 17253 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20111 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21533 | 55 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8827 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9984 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9037 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
View Lastest Price from 2-Bromo-7-hydroxynaphthalene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 2-Bromo-7-hydroxynaphthalene
116230-30-9
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | 2-Bromo-7-hydroxynaphthalene
116230-30-9
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-04-04 | 2-Bromo-7-hydroxynaphthalene
116230-30-9
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 2-Bromo-7-hydroxynaphthalene
116230-30-9
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-Bromo-7-hydroxynaphthalene
116230-30-9
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-Bromo-7-hydroxynaphthalene
116230-30-9
- 98%
- Henan Aochuang Chemical Co.,Ltd.
