2-Chloromethylbenzimidazole
- CAS No.
- 4857-04-9
- Chemical Name:
- 2-Chloromethylbenzimidazole
- Synonyms
- 2-(chloroMethyl)-1H-benzo[d]iMidazole;2-(CHLOROMETHYL)BENZIMIDAZOLE;1-(4-chlorobenzyl)-2-(chloroMethyl)-1H-benzo[d]iMidazole;TIMTEC-BB S;AKOS BBS-00003999;TIMTEC-BB SBB001845;ASINEX-REAG BAS 05306272;CHLOROMETHYLBENZIMIDAZOLE;2-Chloromethylbenzimidazole,95%;2-CHLOROMETHYL-1H-BENZOIMIDAZOLE
- CBNumber:
- CB5128718
- Molecular Formula:
- C8H7ClN2
- Molecular Weight:
- 166.61
- MDL Number:
- MFCD00005602
- MOL File:
- 4857-04-9.mol
- MSDS File:
- SDS
| Melting point | 146-148 °C (dec.)(lit.) |
|---|---|
| Boiling point | 274.83°C (rough estimate) |
| Density | 1.2387 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Storage temp. -20°C |
| pka | 11.18±0.10(Predicted) |
| form | Powder |
| color | Beige to dark yellow |
| Water Solubility | Insoluble in water. |
| InChI | InChI=1S/C8H7ClN2/c9-5-8-10-6-3-1-2-4-7(6)11-8/h1-4H,5H2,(H,10,11) |
| InChIKey | SPMLMLQATWNZEE-UHFFFAOYSA-N |
| SMILES | C1(CCl)NC2=CC=CC=C2N=1 |
| CAS DataBase Reference | 4857-04-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-37/39-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Chloromethylbenzimidazole price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C52055 | 2-(Chloromethyl)benzimidazole 96% | 4857-04-9 | 5g | $59.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | C52055 | 2-(Chloromethyl)benzimidazole 96% | 4857-04-9 | 25g | $129 | 2026-04-30 | Buy |
| Usbiological | 267382 | 2-Chloromethyl benzimidazole Asreported | 4857-04-9 | 5g | $415 | 2026-06-03 | Buy |
| Usbiological | 267382 | 2-Chloromethyl benzimidazole Asreported | 4857-04-9 | 10g | $645 | 2026-06-03 | Buy |
| Usbiological | 267382 | 2-Chloromethyl benzimidazole Asreported | 4857-04-9 | 25g | $899 | 2026-06-03 | Buy |
2-Chloromethylbenzimidazole Chemical Properties, Uses, Production
Chemical Properties
beige to dark yellow powder
Uses
2-(Chloromethyl)benzimidazole is used as intermediate in pharmaceutical , in organic synthesis .
Synthesis
79-11-8
95-54-5
4857-04-9
GENERAL METHOD: A mixture of o-phenylenediamine (0.1 mol) and chloroacetic acid (0.15 mol) in 100 mL of 5N HCl was heated to reflux and stirred continuously for 3-5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently neutralized with sodium bicarbonate solution. The precipitate of 2-chloromethylbenzimidazole formed was collected by filtration, washed several times with water and finally dried to obtain the pure product.
References
[1] Collection of Czechoslovak Chemical Communications, 1991, vol. 56, # 6, p. 1358 - 1360
[2] Revue Roumaine de Chimie, 2016, vol. 61, # 1, p. 15 - 22
[3] Oriental Journal of Chemistry, 2017, vol. 33, # 6, p. 3138 - 3143
[4] Heterocycles, 2002, vol. 57, # 8, p. 1423 - 1432
[5] Journal of the Korean Chemical Society, 2010, vol. 54, # 5, p. 589 - 593
2-Chloromethylbenzimidazole Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Apis Pharmaceutical Technology Co.,Ltd | 13568817957 | dudes@163.com | China | 300 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| Nanbu County Chengxin Technology Co., Ltd. | 0838-5675166 15883665058 | nbcxkj@126.com | China | 956 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
View Latest Price from 2-Chloromethylbenzimidazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | 2-Chloromethylbenzimidazole
4857-04-9
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-05-12 | 2-Chloromethylbenzimidazole
4857-04-9
|
1kg | 98% | 500 kgs | PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD | ||
 |
2021-07-02 | 2-Chloromethylbenzimidazole
4857-04-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 2-Chloromethylbenzimidazole
4857-04-9
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-Chloromethylbenzimidazole
4857-04-9
- $0.00
- 98%
- PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
-
- 2-Chloromethylbenzimidazole
4857-04-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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