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4'-Fluoro-2'-hydroxyacetophenone

4'-Fluoro-2'-hydroxyacetophenone Structure
4'-Fluoro-2'-hydroxyacetophenone structure
CAS No.
1481-27-2
Chemical Name:
4'-Fluoro-2'-hydroxyacetophenone
Synonyms
1-(4-Fluoro-2-hydroxyphenyl)ethan-1-one;1-(4-fluoro-2-hydroxyphenyl)ethanone;4-FLUORO-2-HYDROXYACETOPHENONE;4'-Fluoro-2'-hydroxy;4-FLUORO-2-HYDROXYACETOPHE;uoro-2'-hydroxyacetophenone;4-Fluoro-2-hydroxyacethophenone;4'-Fluoro-2'-hydroxyacetophenone;4'-Fluoro-2'-hydroxyacetophenone>4'-Fluoro-2'-hydroxyacetophenone98%
CBNumber:
CB5147045
Molecular Formula:
C8H7FO2
Molecular Weight:
154.14
MDL Number:
MFCD00143203
MOL File:
1481-27-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-25 15:33:52
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4'-Fluoro-2'-hydroxyacetophenone Properties

Melting point 32-34°C
Boiling point 65°C 2mm
Density 1.1850 (estimate)
Flash point 98°C
storage temp. Inert atmosphere,Room Temperature
form powder to lump
pka 9.17±0.10(Predicted)
color White to Almost white
BRN 2249799
InChI InChI=1S/C8H7FO2/c1-5(10)7-3-2-6(9)4-8(7)11/h2-4,11H,1H3
InChIKey HLTBTUXAMVOKIH-UHFFFAOYSA-N
SMILES C(=O)(C1=CC=C(F)C=C1O)C
CAS DataBase Reference 1481-27-2(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39-36
WGK Germany  3
HazardClass  IRRITANT
HS Code  29147000
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

4'-Fluoro-2'-hydroxyacetophenone price More Price(65)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 466964 4′-Fluoro-2′-hydroxyacetophenone 98% 1481-27-2 5g $59.2 2026-04-30 Buy
TCI Chemical F0723 4'-Fluoro-2'-hydroxyacetophenone >97.0%(GC) 1481-27-2 5g $67 2026-04-30 Buy
TCI Chemical F0723 4'-Fluoro-2'-hydroxyacetophenone >97.0%(GC) 1481-27-2 25g $265 2026-04-30 Buy
Biosynth FF36776 4'-Fluoro-2'-hydroxyacetophenone 1481-27-2 0.01kg $150 2026-06-04 Buy
Biosynth FF36776 4'-Fluoro-2'-hydroxyacetophenone 1481-27-2 0.025kg $226.75 2026-06-04 Buy
Product number Packaging Price Buy
466964 5g $59.2 Buy
F0723 5g $67 Buy
F0723 25g $265 Buy
FF36776 0.01kg $150 Buy
FF36776 0.025kg $226.75 Buy

4'-Fluoro-2'-hydroxyacetophenone Chemical Properties,Uses,Production

Chemical Properties

Colorless to yellow liquid

Uses

4′-Fluoro-2′-hydroxyacetophenone may be used in the preparation of series of 4′-fluoro-2′-hydroxychalcones, via aldol condensation with substituted aldehydes followed by cyclization with hydrazine hydrate.

Preparation

Preparation by Fries rearrangement of 3-fluorophenyl acetate with aluminium chloride without solvent at 160–180° (75%) (88–90%).

General Description

4′-Fluoro-2′-hydroxyacetophenone is a substituted acetophenone derivative. Biological Baeyer-Villiger oxidation of 4′-fluoro-2′-hydroxyacetophenone to 4-fluorocatechol by using whole cells of Pseudomonas fluorescens ACB has been reported. Its crystals belong to the monoclinic crystal system and space group P21/n.

4'-Fluoro-2'-hydroxyacetophenone Preparation Products And Raw materials

Raw materials

2',4'-Difluoroacetophenone 1-Acetoxy-3-fluorobenzene 2'-Fluoro-4'-hydroxyacetophenone

Preparation Products

6-Fluoro-3(2H)-benzofuranone 1-(2-ethoxy-4-fluorophenyl)ethanone 4-Fluoro-2-methoxyphenol

4'-Fluoro-2'-hydroxyacetophenone Suppliers

Global( 282)Suppliers
Supplier Tel Email Country ProdList Advantage
Taizhou Wealsun Biotech Co., Ltd 18351140886; 18351140886 wealsunbio@126.com China 139 58
Suzhou Lyran Biopharma And Technology CO.,LTD. 15556287180 15556287180 1184800090@qq.com China 408 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Supplier Advantage
Taizhou Wealsun Biotech Co., Ltd 58
Suzhou Lyran Biopharma And Technology CO.,LTD. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66

View Lastest Price from 4'-Fluoro-2'-hydroxyacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4'-Fluoro-2'-hydroxyacetophenone pictures 2026-06-30 4'-Fluoro-2'-hydroxyacetophenone
1481-27-2
 1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
4'-Fluoro-2'-hydroxyacetophenone pictures 2025-04-04 4'-Fluoro-2'-hydroxyacetophenone
1481-27-2
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
4'-Fluoro-2'-hydroxyacetophenone pictures 2019-09-02 4'-Fluoro-2'-hydroxyacetophenone
1481-27-2
 $1.00 1KG 98% 200kg Career Henan Chemical Co

4'-Fluoro-2'-hydroxyacetophenone Spectrum

4'-Fluoro-2'-hydroxyacetophenone(1481-27-2)1HNMR4'-Fluoro-2'-hydroxyacetophenone(1481-27-2)IR

1481-27-2(4'-Fluoro-2'-hydroxyacetophenone)Related Search:

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4-Aminoacetophenone 2',4',6'-Trihydroxyacetophenone monohydrate 2-Hydroxyacetophenone 7-Fluoro-4-chromanone 1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone
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4-FLUORO-2-HYDROXYACETOPHENONE 4-Fluoro-2-hydroxyacethophenone, 98% 4'-Fluoro-2'-hydroxyacetophenone 98% 4'-Fluoro-2'-hydroxyacetophenone98% 4'-fluoro-2'-hydroxyacetophenone,1-(4-fluoro-2-hydroxyphenyl)ethanone 4-FLUORO-2-HYDROXYACETOPHE uoro-2'-hydroxyacetophenone 1-(4-fluoro-2-hydroxyphenyl)ethanone 4'-Fluoro-2'-hydroxy 4'-Fluoro-2'-hydroxyacetophenone> Ethanone, 1-(4-fluoro-2-hydroxyphenyl)- 4'-Fluoro-2'-hydroxyacetophenone 4-Fluoro-2-hydroxyacethophenone 1-(4-Fluoro-2-hydroxyphenyl)ethan-1-one 1481-27-2 1181-27-2 FC6H3OHCOCH3 Organic Building Blocks Ketones Building Blocks Carbonyl Compounds C7 to C8 Aromatic Acetophenones & Derivatives (substituted) ketone Adehydes, Acetals & Ketones Fluorine Compounds Phenols C7 to C8 Carbonyl Compounds Ketones