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4-Methyl-6-chloro pyrimidine

4-Methyl-6-chloro pyrimidine Structure
4-Methyl-6-chloro pyrimidine structure
CAS No.
3435-25-4
Chemical Name:
4-Methyl-6-chloro pyrimidine
Synonyms
4-CHLORO-6-METHYLPYRIMIDINE;AKOS BBS-00002134;6-Chloro-4-methylpyrimidine;4-Methyl-6-chloro pyrimidine;4-Chloro-6-methyl-1,3-diazine;Pyrimidine, 4-chloro-6-methyl-;4-Chloro-6-methylpyrimidine,97%;4-chloro-6-methylpyrimidine(SALTDATA: FREE);4-METHYL-6-CHLORO PYRIMIDINE ISO 9001：2015 REACH;Pyrimidine, 4-chloro-6-methyl- (6CI,7CI,8CI,9CI)
CBNumber:
CB5161786
Molecular Formula:
C5H5ClN2
Molecular Weight:
128.56
MDL Number:
MFCD02322991
MOL File:
3435-25-4.mol
MSDS File:
SDS
Last updated:2026-09-12 18:53:14
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4-Methyl-6-chloro pyrimidine Properties

Melting point 151-152℃
Boiling point 195℃
Density 1.234
Flash point 90℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form Solid
pka 0.83±0.17(Predicted)
color Pale yellow
Water Solubility Slightly soluble in water.

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
HS Code  2933599590
NFPA 704
1
2 0

4-Methyl-6-chloro pyrimidine price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FM11227 4-Methyl-6-chloropyrimidine 3435-25-4 5g $206.65 2026-06-04 Buy
Biosynth FM11227 4-Methyl-6-chloropyrimidine 3435-25-4 10g $326.8 2026-06-04 Buy
Biosynth FM11227 4-Methyl-6-chloropyrimidine 3435-25-4 25g $480.75 2026-06-04 Buy
Biosynth FM11227 4-Methyl-6-chloropyrimidine 3435-25-4 50g $1249.5 2026-06-04 Buy
Biosynth FM11227 4-Methyl-6-chloropyrimidine 3435-25-4 100g $1730 2026-06-04 Buy
Product number Packaging Price Buy
FM11227 5g $206.65 Buy
FM11227 10g $326.8 Buy
FM11227 25g $480.75 Buy
FM11227 50g $1249.5 Buy
FM11227 100g $1730 Buy

4-Methyl-6-chloro pyrimidine Chemical Properties,Uses,Production

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Synthesis

4,6-Dichloropyrimidine

1193-21-1

Methylmagnesium Bromide

75-16-1

4-METHYL-6-CHLORO PYRIMIDINE

3435-25-4

To a solution of 4,6-dichloropyrimidine (1.0 g, 6.71 mmol) in tetrahydrofuran (30 mL) was added sequentially 1-methyl-2-pyrrolidinone (3.2 mL, 6.71 mmol), iron(III) acetylacetonate (0.119 g, 0.336 mmol) and methylmagnesium bromide (2.237 mL, 6.71 mmol). The reaction mixture was stirred at room temperature for 3 h. After completion of the reaction, the reaction was quenched with water and extracted with ethyl acetate (100 mL). The organic layer was separated and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography (eluent: 20% ethyl acetate/hexane) to afford 4-chloro-6-methylpyrimidine (0.6 g, 3.08 mmol, 46% yield) as a colorless gelatinous liquid.LC-MS (ESI) analysis showed m/z 129.0 [M+H]+ (calculated value C5H6ClN2: 129.0); LC/MS retention time ( Method D): 1.36 min.

References

[1] Patent: WO2017/59085, 2017, A1. Location in patent: Page/Page column 403; 404

4-Methyl-6-chloro pyrimidine Preparation Products And Raw materials

Raw materials

4,6-Dichloropyrimidine Methylmagnesium Bromide Tetrahydrofuran N-Methyl-2-pyrrolidone Ferric acetylacetonate

Preparation Products

2-Chloro-6-methylpyrazine Pyrimidine, 4-dimethylamino-6-methyl- (6CI) 4(1H)-Pyrimidinethione, 6-methyl- (9CI)

4-Methyl-6-chloro pyrimidine Suppliers

Global( 175)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
China Langchem Inc. 0086-21-58956006 China 7798 57
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
ShangHai DEMO Chemical Co.,Ltd 57
Capot Chemical Co., Ltd 66
Jia Xing Isenchem Co.,Ltd 66
Pure Chemistry Scientific Inc. 62
Accela ChemBio Co.,Ltd. 64
Shanghai Longsheng chemical Co.,Ltd. 59
Shanghai Hanhong Scientific Co.,Ltd. 64
China Langchem Inc. 57

View Lastest Price from 4-Methyl-6-chloro pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Chloro-6-methylpyrimidine pictures 2026-09-02 4-Chloro-6-methylpyrimidine
3435-25-4
 $1.00-200.00 1KG 99%, 99.5% Sublimated Henan Fengda Chemical Co., Ltd
4-METHYL-6-CHLORO PYRIMIDINE pictures 2026-08-20 4-METHYL-6-CHLORO PYRIMIDINE
3435-25-4
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
4-Chloro-6-MethylpyriMidine pictures 2022-04-22 4-Chloro-6-MethylpyriMidine
3435-25-4
 98%min 100kgs/month Shanghai Rlavie Technology Co ltd

4-Methyl-6-chloro pyrimidine Spectrum

4-METHYL-6-CHLORO PYRIMIDINE(3435-25-4)1HNMR

3435-25-4(4-Methyl-6-chloro pyrimidine)Related Search:

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AKOS BBS-00002134 Pyrimidine, 4-chloro-6-methyl- (6CI,7CI,8CI,9CI) 4-chloro-6-methylpyrimidine(SALTDATA: FREE) 6-Chloro-4-methylpyrimidine 4-Chloro-6-methyl-1,3-diazine Pyrimidine, 4-chloro-6-methyl- 4-Chloro-6-methylpyrimidine,97% 4-METHYL-6-CHLORO PYRIMIDINE ISO 9001：2015 REACH 4-CHLORO-6-METHYLPYRIMIDINE 4-Methyl-6-chloro pyrimidine 3435-25-4 Heterocycle-Pyrimidine series PYRIMIDINE Halides Pyrazines, Pyrimidines & Pyridazines