4-(Bromomethyl)tetrahydropyran
- CAS No.
- 125552-89-8
- Chemical Name:
- 4-(Bromomethyl)tetrahydropyran
- Synonyms
- 4-(broMoMethyl)oxane;4-bromomethytetrahydropyran;4-(BroMoMethyl)tetrahydro...;4-BROMOMETHYLTETRAHYDROPYRAN;4-(Bromomethyl)tetrahydropyrane;4-Bromomethyltetrahydropyran, 96%;4-(Bromomethyl)tetrahydropyran ,97%;4-(BROMOMETHYL)-TETRAHYDRO-2H-PYRAN;2H-Pyran, 4-(broMoMethyl)tetrahydro-;Tetrahydro-2H-pyran-4-yl-MethylbroMide
- CBNumber:
- CB0436966
- Molecular Formula:
- C6H11BrO
- Molecular Weight:
- 179.05
- MDL Number:
- MFCD03788561
- MOL File:
- 125552-89-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-(Bromomethyl)tetrahydro-2H-pyran min. 98.0 % | B6596 | 5G | $109 |
| 4-(Bromomethyl)tetrahydro-2H-pyran min. 98.0 % | B6596 | 25G | $327 |
| 4-Bromomethyltetrahydropyran | B697768 | 500mg | $65 |
| 4-(Bromomethyl)tetrahydropyran 95% | 037029 | 5g | $70 |
| 4-(Bromomethyl)tetrahydropyran 97% | 069250 | 5g | $71 |
| More product size | |||
| Boiling point | 88 °C |
|---|---|
| Density | 1.359±0.06 g/cm3(Predicted) |
| refractive index | 1.49 |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| form | liquid |
| color | Light beige/brown |
| InChI | InChI=1S/C6H11BrO/c7-5-6-1-3-8-4-2-6/h6H,1-5H2 |
| InChIKey | LMOOYAKLEOGKJR-UHFFFAOYSA-N |
| SMILES | C1OCCC(CBr)C1 |
| CAS DataBase Reference | 125552-89-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| Hazard Codes | C,Xn | |||||||||
| Risk Statements | 36/37/38-34-22 | |||||||||
| Safety Statements | 26-36/37/39-45-23 | |||||||||
| RIDADR | 3265 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29339900 | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
4-(Bromomethyl)tetrahydropyran price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B6596 | 4-(Bromomethyl)tetrahydro-2H-pyran min. 98.0 % | 125552-89-8 | 5G | $109 | 2026-03-19 | Buy |
| TCI Chemical | B6596 | 4-(Bromomethyl)tetrahydro-2H-pyran min. 98.0 % | 125552-89-8 | 25G | $327 | 2026-03-19 | Buy |
| TRC | B697768 | 4-Bromomethyltetrahydropyran | 125552-89-8 | 500mg | $65 | 2021-12-16 | Buy |
| Oakwood | 037029 | 4-(Bromomethyl)tetrahydropyran 95% | 125552-89-8 | 5g | $70 | 2021-12-16 | Buy |
| Matrix Scientific | 069250 | 4-(Bromomethyl)tetrahydropyran 97% | 125552-89-8 | 5g | $71 | 2021-12-16 | Buy |
4-(Bromomethyl)tetrahydropyran Chemical Properties,Uses,Production
Chemical Properties
Viscous liquid
Uses
4-(Bromomethyl)tetrahydropyran is an important organic synthesis intermediate, widely used in the fields of medicine, pesticides and dyes. It can be used to synthesize a variety of biologically active compounds, such as antibacterial agents, anti-tumor drugs, nervous system drugs and fluorescent dyes. In addition, 4-(Bromomethyl)tetrahydropyran can also be used to synthesize organic pigments and functional materials.
Application
4-(Bromomethyl)tetrahydropyran can be used as an intermediate in the synthesis of compounds with antibacterial activity. For example, it can be used to introduce other functional groups through nucleophilic substitution reactions to construct molecules with antibacterial activity. Certain compounds containing tetrahydropyran rings have been studied for their potential to inhibit bacterial growth and reproduction.
Synthesis
To a solution of Tetrahydropyran-4-methanol and N-bromobutanimide (NBS) in DCM was added PPh3 at 0°C. The reaction mixture was stirred at room temperature for 1–2h. The resulting mixture was washed with water (20mL) and brine (3×20mL). The organic layer was concentrated and the residue was purified by silica gel flash chromatography (eluting with ethyl acetate in petroleum ether 2–5%) to give 4-(Bromomethyl)tetrahydropyran as a colorless oil.
References
[1] European Journal of Medicinal Chemistry, 2018, vol. 158, p. 896 - 916
[2] Journal of the American Chemical Society, 1950, vol. 72, p. 5512,5514
[3] Justus Liebigs Annalen der Chemie, 1937, vol. 532, p. 80
[4] Chem.Abstr., 1940, p. 4396
[5] Journal of the American Chemical Society, 1993, vol. 115, # 18, p. 8401 - 8408
4-(Bromomethyl)tetrahydropyran Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Yongzeng Technology Co.,Ltd | +8613818947575 | sales@yongzchem.com | China | 142 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21591 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2176 | 58 |
| BTC Nantong Pharmaceuticals Technology Co.,Ltd | +86-0513-81283365 | Info@btcpharm.com | China | 251 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 4-(Bromomethyl)tetrahydropyran manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-30 | 4-BroMoMethyltetrahydropyran
125552-89-8
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
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2026-04-29 | 4-(Bromomethyl) tetrahydropyran
125552-89-8
|
US $1500.00 / kg | 1kg | 99%min | 100kgs | Shanghai Yongzeng Technology Co.,Ltd | |
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2025-12-01 | 4-(Bromomethyl)tetrahydropyran
125552-89-8
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-

- 4-BroMoMethyltetrahydropyran
125552-89-8
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- 4-(Bromomethyl) tetrahydropyran
125552-89-8
- US $1500.00 / kg
- 99%min
- Shanghai Yongzeng Technology Co.,Ltd
-

- 4-(Bromomethyl)tetrahydropyran
125552-89-8
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
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