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4-(Bromomethyl)tetrahydropyran

CAS No.
125552-89-8
Chemical Name:
4-(Bromomethyl)tetrahydropyran
Synonyms
4-(broMoMethyl)oxane;4-bromomethytetrahydropyran;4-(BroMoMethyl)tetrahydro...;4-BROMOMETHYLTETRAHYDROPYRAN;4-(Bromomethyl)tetrahydropyrane;4-Bromomethyltetrahydropyran, 96%;4-(Bromomethyl)tetrahydropyran ,97%;4-(BROMOMETHYL)-TETRAHYDRO-2H-PYRAN;2H-Pyran, 4-(broMoMethyl)tetrahydro-;Tetrahydro-2H-pyran-4-yl-MethylbroMide
CBNumber:
CB0436966
Molecular Formula:
C6H11BrO
Molecular Weight:
179.05
MDL Number:
MFCD03788561
MOL File:
125552-89-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:25
Product description Number Pack Size Price
4-(Bromomethyl)tetrahydro-2H-pyran min. 98.0 % B6596 5G $109
4-(Bromomethyl)tetrahydro-2H-pyran min. 98.0 % B6596 25G $327
4-Bromomethyltetrahydropyran B697768 500mg $65
4-(Bromomethyl)tetrahydropyran 95% 037029 5g $70
4-(Bromomethyl)tetrahydropyran 97% 069250 5g $71
More product size

4-(Bromomethyl)tetrahydropyran Properties

Boiling point 88 °C
Density 1.359±0.06 g/cm3(Predicted)
refractive index 1.49
storage temp. Inert atmosphere,Store in freezer, under -20°C
form liquid
color Light beige/brown
InChI InChI=1S/C6H11BrO/c7-5-6-1-3-8-4-2-6/h6H,1-5H2
InChIKey LMOOYAKLEOGKJR-UHFFFAOYSA-N
SMILES C1OCCC(CBr)C1
CAS DataBase Reference 125552-89-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  C,Xn
Risk Statements  36/37/38-34-22
Safety Statements  26-36/37/39-45-23
RIDADR  3265
Hazard Note  Irritant
HazardClass  8
PackingGroup 
HS Code  29339900
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
3 0

4-(Bromomethyl)tetrahydropyran price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B6596 4-(Bromomethyl)tetrahydro-2H-pyran min. 98.0 % 125552-89-8 5G $109 2026-03-19 Buy
TCI Chemical B6596 4-(Bromomethyl)tetrahydro-2H-pyran min. 98.0 % 125552-89-8 25G $327 2026-03-19 Buy
TRC B697768 4-Bromomethyltetrahydropyran 125552-89-8 500mg $65 2021-12-16 Buy
Oakwood 037029 4-(Bromomethyl)tetrahydropyran 95% 125552-89-8 5g $70 2021-12-16 Buy
Matrix Scientific 069250 4-(Bromomethyl)tetrahydropyran 97% 125552-89-8 5g $71 2021-12-16 Buy
Product number Packaging Price Buy
B6596 5G $109 Buy
B6596 25G $327 Buy
B697768 500mg $65 Buy
037029 5g $70 Buy
069250 5g $71 Buy

4-(Bromomethyl)tetrahydropyran Chemical Properties,Uses,Production

Chemical Properties

Viscous liquid

Uses

4-(Bromomethyl)tetrahydropyran is an important organic synthesis intermediate, widely used in the fields of medicine, pesticides and dyes. It can be used to synthesize a variety of biologically active compounds, such as antibacterial agents, anti-tumor drugs, nervous system drugs and fluorescent dyes. In addition, 4-(Bromomethyl)tetrahydropyran can also be used to synthesize organic pigments and functional materials.

Application

4-(Bromomethyl)tetrahydropyran can be used as an intermediate in the synthesis of compounds with antibacterial activity. For example, it can be used to introduce other functional groups through nucleophilic substitution reactions to construct molecules with antibacterial activity. Certain compounds containing tetrahydropyran rings have been studied for their potential to inhibit bacterial growth and reproduction.

Synthesis

To a solution of Tetrahydropyran-4-methanol and N-bromobutanimide (NBS) in DCM was added PPh3 at 0°C. The reaction mixture was stirred at room temperature for 1–2h. The resulting mixture was washed with water (20mL) and brine (3×20mL). The organic layer was concentrated and the residue was purified by silica gel flash chromatography (eluting with ethyl acetate in petroleum ether 2–5%) to give 4-(Bromomethyl)tetrahydropyran as a colorless oil.

References

[1] European Journal of Medicinal Chemistry, 2018, vol. 158, p. 896 - 916
[2] Journal of the American Chemical Society, 1950, vol. 72, p. 5512,5514
[3] Justus Liebigs Annalen der Chemie, 1937, vol. 532, p. 80
[4] Chem.Abstr., 1940, p. 4396
[5] Journal of the American Chemical Society, 1993, vol. 115, # 18, p. 8401 - 8408

132291-95-3
125552-89-8
Synthesis of 4-(Bromomethyl)tetrahydropyran from Tetrahydropyran-4-ylmethyl methanesulfonate
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View Lastest Price from 4-(Bromomethyl)tetrahydropyran manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-BroMoMethyltetrahydropyran pictures 2026-04-30 4-BroMoMethyltetrahydropyran
125552-89-8
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
4-(Bromomethyl) tetrahydropyran pictures 2026-04-29 4-(Bromomethyl) tetrahydropyran
125552-89-8
US $1500.00 / kg 1kg 99%min 100kgs Shanghai Yongzeng Technology Co.,Ltd
4-(Bromomethyl)tetrahydropyran pictures 2025-12-01 4-(Bromomethyl)tetrahydropyran
125552-89-8
US $0.00 / kg 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-(BROMOMETHYL)-TETRAHYDRO-2H-PYRAN 4-BROMOMETHYLTETRAHYDROPYRAN 4-(Bromomethyl)tetrahydropyrane 4-(Bromomethyl)tetrahydropyran ,97% 4-(Bromomethyl)tetrahydro-2H-pyran 97% 4-bromomethytetrahydropyran Tetrahydro-2H-pyran-4-yl-MethylbroMide 4-(BroMoMethyl)tetrahydro... (Tetrahydro-2H-pyran-4-yl)methyl bromide, 4-(Bromomethyl)oxane 4-(broMoMethyl)oxane 2H-Pyran, 4-(broMoMethyl)tetrahydro- 1-(Tetrahydro-2H-pyran-4-yl)methylbromide 4-BROMOMETHYLTETRAHYDROPYRAN ISO 9001:2015 REACH 4-Bromomethyltetrahydropyran, 96% 125552-89-8 C6H11BrO Heterocyclic Compounds blocks Bromides Heterocycles Halides