Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Bromo-5-chloropyridine

2-Bromo-5-chloropyridine

2-Bromo-5-chloropyridine Structure
2-Bromo-5-chloropyridine structure
CAS No.
40473-01-6
Chemical Name:
2-Bromo-5-chloropyridine
Synonyms
IFLAB-BB F2124-0201;2-broMo-5-chloropyridin;2-Brome-5-chloropyridine;2-BROMO-5-CHLOROPYRIDINE;5-Chloro-2-bromopyridine;2-BroMoo-5-chloropyridine;2-Beromo-5-chloropyridine;Pyridine, 2-bromo-5-chloro-;2-broMo -5-chlorine pyridine;2-Bromo-5-chloropyridine,98%
CBNumber:
CB9384264
Molecular Formula:
C5H3BrClN
Molecular Weight:
192.44
MDL Number:
MFCD00234006
MOL File:
40473-01-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:07:08
Request For Quotation

2-Bromo-5-chloropyridine Properties

Melting point 65-69 °C
Boiling point 128 °C / 16mmHg
Density 1.736±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka -1.49±0.10(Predicted)
form Powder
color Beige to yellow-brown
Water Solubility Slightly soluble in water.
InChI InChI=1S/C5H3BrClN/c6-5-2-1-4(7)3-8-5/h1-3H
InChIKey BZUUVQCSPHPUQA-UHFFFAOYSA-N
SMILES C1(Br)=NC=C(Cl)C=C1
CAS DataBase Reference 40473-01-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H302-H312-H332-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn,Xi
Risk Statements  36/37/38-20/22-20/2236/37/38-20/21/22
Safety Statements  36/37/39-26-22-22 26 36/37/39-36
RIDADR  Cool, dry,tightly closed
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
2 0

2-Bromo-5-chloropyridine price More Price(80)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T138401 2-BROMO-5-CHLOROPYRIDINE AldrichCPR 40473-01-6 5MG $152 2026-04-30 Buy
TCI Chemical B2763 2-Bromo-5-chloropyridine >98.0%(GC) 40473-01-6 1g $18 2026-04-30 Buy
TCI Chemical B2763 2-Bromo-5-chloropyridine >98.0%(GC) 40473-01-6 5g $30 2026-04-30 Buy
Biosynth FB64674 2-Bromo-5-chloropyridine 40473-01-6 0.25kg $297 2026-06-04 Buy
Biosynth FB64674 2-Bromo-5-chloropyridine 40473-01-6 0.5kg $495 2026-06-04 Buy
Product number Packaging Price Buy
T138401 5MG $152 Buy
B2763 1g $18 Buy
B2763 5g $30 Buy
FB64674 0.25kg $297 Buy
FB64674 0.5kg $495 Buy

2-Bromo-5-chloropyridine Chemical Properties, Uses, Production

Chemical Properties

white to light yellow crystal powder

Uses

It is an important organic intermediate used in agrochemicals, pharmaceuticals and dyestuff fields. It is also used in the synthesis of novel halopyridinylboronic acids and esters.

Synthesis

2-Amino-5-chloropyridine

1072-98-6

2-Bromo-5-chloropyridine

40473-01-6

General procedure for the synthesis of 2-bromo-5-chloropyridine from 2-amino-5-chloropyridine: [Ref. Example 25] 5-(5-chloro-2-pyridinyl)-1-(3-pyridinyl)-1H-pyrazole-3-carboxylic acid; [show image] 1) Hydrogen bromide (12 ml, 47% aqueous solution) was slowly added to hydrogen bromide (12 ml, 47% aqueous solution) at 0 °C in a hydrobromic acid containing 2-amino-5-chloropyridine (5 g) ( 50 ml, 47%) solution. Subsequently, a solution of sodium nitrite (15 g) dissolved in water (20 ml) was added dropwise to the reaction mixture. The reaction solution was stirred at 0°C for 1 h. After that, a solution of sodium hydroxide (32 g) in water (80 ml) and ethyl acetate was added for extraction. The organic and aqueous phases were separated and the organic phase was dried over anhydrous sodium sulfate. After filtration, the solvent was removed by concentration under reduced pressure to give 2-bromo-5-chloropyridine (6.8 g, 91% yield) as a white solid. The product was characterized by 1H-NMR (400 MHz, CDCl3): δ 7.44 (1H, d, J = 8.42 Hz), 7.54 (1H, m), 8.36 (1H, s).

References

[1] Chemistry of Heterocyclic Compounds, 2017, vol. 53, # 2, p. 196 - 206
[2] Khim. Geterotsikl. Soedin., 2017, vol. 53, # 2, p. 196 - 206,11
[3] Patent: EP1698626, 2006, A1. Location in patent: Page/Page column 41
[4] Patent: EP1762568, 2007, A1. Location in patent: Page/Page column 24-25
[5] Patent: US5750545, 1998, A

2-Bromo-5-chloropyridine synthesis

1072-98-6
40473-01-6
Synthesis of 2-Bromo-5-chloropyridine from 2-Amino-5-chloropyridine

2-Bromo-5-chloropyridine Preparation Products And Raw materials

Raw materials

5-Chloro-2-hydroxypyridine 2-Bromo-1,3-benzothiazole 2,5-Dichloropyridine Sodium nitrite Sodium hydroxide
Hydrogen bromide Ethyl acetate 2-Amino-5-chloropyridine

1of2

Preparation Products

5-Chloropyridine-2-boronic acid 5-Chloropyridine-2-carboxylic acid 3-Amino-6-morpholinopyridine 5-Chloropyridine-2-boronic acid pinacol ester 4-(5-Chloropyridin-2-yl)morpholine
5-Chloro-2'-fluoro-[2,3']-bipyridine Pyridine, 5-chloro-4-iodo-2-(trifluoroMethyl)-

1of2

2-Bromo-5-chloropyridine Suppliers

Global Suppliers ( 523)
Supplier Tel Email Country ProdList Advantage
Beijing Sintong Pharma Technology Co., Ltd. 13466647005 47652055@qq.com China 393 58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. 13396369453 18678026865 sdfantai@163.com China 904 58
Sanjing New Materials Technology (Taizhou) Co., Ltd. 13852622638 1048979734@qq.com China 778 58
Dalian Dacheng chemical Co.ltd 15898130392 1664751898@qq.com China 17 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Supplier Advantage
Beijing Sintong Pharma Technology Co., Ltd. 58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. 58
Sanjing New Materials Technology (Taizhou) Co., Ltd. 58
Dalian Dacheng chemical Co.ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81

View Latest Price from 2-Bromo-5-chloropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-5-chloropyridine pictures 2026-09-02 2-Bromo-5-chloropyridine
40473-01-6
 $8.00 1KG 99% Henan Fengda Chemical Co., Ltd
2-Bromo-5-chloropyridine pictures 2026-08-20 2-Bromo-5-chloropyridine
40473-01-6
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Bromo-5-chloropyridine pictures 2026-06-30 2-Bromo-5-chloropyridine
40473-01-6
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd

2-Bromo-5-chloropyridine Spectrum

2-Bromo-5-chloropyridine(40473-01-6)MS2-Bromo-5-chloropyridine(40473-01-6)1HNMR2-Bromo-5-chloropyridine(40473-01-6)13CNMR2-Bromo-5-chloropyridine(40473-01-6)IR12-Bromo-5-chloropyridine(40473-01-6)IR2

40473-01-6 (2-Bromo-5-chloropyridine) Related Search:

2-Chloro-5-chloromethylpyridine 2-Bromo-5-fluoropyridine Pentachloropyridine 2-Bromopyridine BCDMH
Clopidol Chlorobromoisocyanurate 2-Chloro-3-cyanopyridine 1-Hexadecylpyridinium bromide 2-Bromo-5-methylpyridine
2-Bromo-6-(trifluoromethyl)pyridine 2-Bromo-6-methylpyridine 2-Bromo-5-nitropyridine 2-Bromo-5-(trifluoromethyl)pyridine 5-Amino-2-bromopyridine
2-Bromo-5-methoxypyridine 2-Bromo-5-iodobenzyl alcohol 6-Bromonicotinic acid

1of4

2-BROMO-5-CHLOROPYRIDINE 2-Brome-5-chloropyridine IFLAB-BB F2124-0201 2-BROMO-5-CHLOROPYRIDINE, 98.5% 2-Bromo-5-chloropyridine,98% 5-Chloro-2-bromopyridine 2-BroMoo-5-chloropyridine 2-BroMo-5-chloropyridine, 98% 5GR 2-broMo-5-chloropyridin 2-broMo -5-chlorine pyridine 2-BroMo-5-chloropyridine, 97.0%(GC) 2 - broMine - 5 - chloro pyridine 2-Beromo-5-chloropyridine Pyridine, 2-bromo-5-chloro- 2-Bromo-5-chloropyridine > 2-Bromo-5-chloropyridine ISO 9001：2015 REACH 40473-01-6 40473-01-06 C3H3BrClN C5H3BrC1N C4H2BrCIN Chloropyridines Bromopyridines Halopyridines Halides Pyridines, Pyrimidines, Purines and Pteredines Bromopyridines Chloropyridines Halopyridines Boronic Acid blocks Bromides Pyridines Pyridine Pyridine Series bc0001