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2-Bromo-5-chloropyridine

2-Bromo-5-chloropyridine structure

CAS No.: 40473-01-6

Chemical Name:: 2-Bromo-5-chloropyridine

Synonyms: IFLAB-BB F2124-0201;2-broMo-5-chloropyridin;2-Brome-5-chloropyridine;2-BROMO-5-CHLOROPYRIDINE;5-Chloro-2-bromopyridine;2-BroMoo-5-chloropyridine;2-Beromo-5-chloropyridine;Pyridine, 2-bromo-5-chloro-;2-broMo -5-chlorine pyridine;2-Bromo-5-chloropyridine,98%

CBNumber:: CB9384264

Molecular Formula:: C5H3BrClN

Molecular Weight:: 192.44

MDL Number:: MFCD00234006

MOL File:: 40473-01-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-20 15:45:06

Product description	Number	Pack Size	Price
2-BROMO-5-CHLOROPYRIDINE AldrichCPR	T138401	5MG	$152
2-Bromo-5-chloropyridine >98.0%(GC)	B2763	1g	$18
2-Bromo-5-chloropyridine >98.0%(GC)	B2763	5g	$30
2-Bromo-5-chloropyridine ≥97%(GC)	28243	25G	$22.03
2-Bromo-5-chloropyridine ≥97%(GC)	28243	100G	$73.71
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2-Bromo-5-chloropyridine Properties

Melting point	65-69 °C
Boiling point	128 °C / 16mmHg
Density	1.736±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	Powder
pka	-1.49±0.10(Predicted)
color	Beige to yellow-brown
Water Solubility	Slightly soluble in water.
InChI	InChI=1S/C5H3BrClN/c6-5-2-1-4(7)3-8-5/h1-3H
InChIKey	BZUUVQCSPHPUQA-UHFFFAOYSA-N
SMILES	C1(Br)=NC=C(Cl)C=C1
CAS DataBase Reference	40473-01-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H302-H312-H332-H335

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Xn,Xi

Risk Statements

36/37/38-20/22-20/2236/37/38-20/21/22

Safety Statements

36/37/39-26-22-22 26 36/37/39-36

RIDADR

Cool, dry,tightly closed

HazardClass

IRRITANT

HS Code

29339900

NFPA 704

	1
2		0

2-Bromo-5-chloropyridine price More Price(60)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T138401	2-BROMO-5-CHLOROPYRIDINE AldrichCPR	40473-01-6	5MG	$152	2026-04-30	Buy
TCI Chemical	B2763	2-Bromo-5-chloropyridine >98.0%(GC)	40473-01-6	1g	$18	2026-04-30	Buy
TCI Chemical	B2763	2-Bromo-5-chloropyridine >98.0%(GC)	40473-01-6	5g	$30	2026-04-30	Buy
Chem-Impex	28243	2-Bromo-5-chloropyridine ≥97%(GC)	40473-01-6	25G	$22.03	2026-05-19	Buy
Chem-Impex	28243	2-Bromo-5-chloropyridine ≥97%(GC)	40473-01-6	100G	$73.71	2026-05-19	Buy

Product number	Packaging	Price	Buy
T138401	5MG	$152	Buy
B2763	1g	$18	Buy
B2763	5g	$30	Buy
28243	25G	$22.03	Buy
28243	100G	$73.71	Buy

2-Bromo-5-chloropyridine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

It is an important organic intermediate used in agrochemicals, pharmaceuticals and dyestuff fields. It is also used in the synthesis of novel halopyridinylboronic acids and esters.

Synthesis

1072-98-6

40473-01-6

General procedure for the synthesis of 2-bromo-5-chloropyridine from 2-amino-5-chloropyridine: [Ref. Example 25] 5-(5-chloro-2-pyridinyl)-1-(3-pyridinyl)-1H-pyrazole-3-carboxylic acid; [show image] 1) Hydrogen bromide (12 ml, 47% aqueous solution) was slowly added to hydrogen bromide (12 ml, 47% aqueous solution) at 0 °C in a hydrobromic acid containing 2-amino-5-chloropyridine (5 g) ( 50 ml, 47%) solution. Subsequently, a solution of sodium nitrite (15 g) dissolved in water (20 ml) was added dropwise to the reaction mixture. The reaction solution was stirred at 0°C for 1 h. After that, a solution of sodium hydroxide (32 g) in water (80 ml) and ethyl acetate was added for extraction. The organic and aqueous phases were separated and the organic phase was dried over anhydrous sodium sulfate. After filtration, the solvent was removed by concentration under reduced pressure to give 2-bromo-5-chloropyridine (6.8 g, 91% yield) as a white solid. The product was characterized by 1H-NMR (400 MHz, CDCl3): δ 7.44 (1H, d, J = 8.42 Hz), 7.54 (1H, m), 8.36 (1H, s).

References

[1] Chemistry of Heterocyclic Compounds, 2017, vol. 53, # 2, p. 196 - 206
[2] Khim. Geterotsikl. Soedin., 2017, vol. 53, # 2, p. 196 - 206,11
[3] Patent: EP1698626, 2006, A1. Location in patent: Page/Page column 41
[4] Patent: EP1762568, 2007, A1. Location in patent: Page/Page column 24-25
[5] Patent: US5750545, 1998, A

2-Bromo-5-chloropyridine synthesis

Synthesis of 2-Bromo-5-chloropyridine from 2-Amino-5-chloropyridine

2-Bromo-5-chloropyridine Preparation Products And Raw materials

Raw materials

5-CHLORO-2-HYDROXYPYRIDINE 2-Bromo-1,3-benzothiazole 2,5-Dichloropyridine Sodium nitrite Sodium hydroxide

Hydrogen bromide Ethyl acetate 2-Amino-5-chloropyridine

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Preparation Products

5-Chloropyridine-2-boronic acid 5-Chloropyridine-2-carboxylic acid 3-Amino-6-morpholinopyridine 5-CHLOROPYRIDINE-2-BORONIC ACID PINACOL ESTER 4-(5-Chloropyridin-2-yl)morpholine

5-CHLORO-2'-FLUORO-[2,3']-BIPYRIDINE Pyridine, 5-chloro-4-iodo-2-(trifluoroMethyl)-

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2-Bromo-5-chloropyridine Suppliers

Global( 519)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Jinan Carbotang Biotech Co.,Ltd.	58
Shandong chuangyingchemical Co., Ltd.	58

View Lastest Price from 2-Bromo-5-chloropyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-01	2-Bromo-5-chloropyridine 40473-01-6	US $0.00-0.00 / KG	1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-11-18	2-Bromo-5-chloropyridine 40473-01-6	US $1.10 / g	1g	99.00%	100 Tons min	Dideu Industries Group Limited
2025-09-25	2-Bromo-5-chloropyridine 40473-01-6	US $8.00-0.80 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd

2-Bromo-5-chloropyridine
40473-01-6
US $0.00-0.00 / KG
98.0%
Shaanxi Dideu New Materials Co. Ltd

2-Bromo-5-chloropyridine
40473-01-6
US $1.10 / g
99.00%
Dideu Industries Group Limited

2-Bromo-5-chloropyridine
40473-01-6
US $8.00-0.80 / KG
99%
Henan Fengda Chemical Co., Ltd

2-Bromo-5-chloropyridine Spectrum

2-Bromo-5-chloropyridine(40473-01-6)MS 2-Bromo-5-chloropyridine(40473-01-6)¹HNMR 2-Bromo-5-chloropyridine(40473-01-6)¹³CNMR 2-Bromo-5-chloropyridine(40473-01-6)IR1 2-Bromo-5-chloropyridine(40473-01-6)IR2

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2-Bromo-5-methylpyridine 2-Bromo-6-(trifluoromethyl)pyridine 2-Bromo-6-methylpyridine 2-BROMO-5-IODOBENZYL ALCOHOL 2-Bromo-5-nitropyridine

2-Bromo-5-(trifluoromethyl)pyridine 5-Amino-2-bromopyridine 6-Bromonicotinic acid

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2-BROMO-5-CHLOROPYRIDINE 2-Brome-5-chloropyridine IFLAB-BB F2124-0201 2-BROMO-5-CHLOROPYRIDINE, 98.5% 2-Bromo-5-chloropyridine,98% 5-Chloro-2-bromopyridine 2-BroMoo-5-chloropyridine 2-BroMo-5-chloropyridine, 98% 5GR 2-broMo-5-chloropyridin 2-broMo -5-chlorine pyridine 2-BroMo-5-chloropyridine, 97.0%(GC) 2 - broMine - 5 - chloro pyridine 2-Beromo-5-chloropyridine Pyridine, 2-bromo-5-chloro- 2-Bromo-5-chloropyridine > 2-Bromo-5-chloropyridine ISO 9001：2015 REACH 40473-01-6 40473-01-06 C3H3BrClN C5H3BrC1N C4H2BrCIN Chloropyridines Bromopyridines Halopyridines Halides Pyridines, Pyrimidines, Purines and Pteredines Bromopyridines Chloropyridines Halopyridines Boronic Acid blocks Bromides Pyridines Pyridine Pyridine Series bc0001