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2,3,4-Trimethoxybenzoic acid

2,3,4-Trimethoxybenzoic acid structure

CAS No.: 573-11-5

Chemical Name:: 2,3,4-Trimethoxybenzoic acid

Synonyms: AKOS 214-77;RARECHEM AL BO 0027;LABOTEST-BB LT00454915;2,3,4-Trimethoxybenzoic;Trimetazidine Impurity L;2,3,4-trimethoxybenzoate;Trimetazidine Impurity 4;Trimetazidine Impurity 19;2,3,4-TRIMETHOXYBENZOIC ACID;Benzoic acid, 2,3,4-trimethoxy-

CBNumber:: CB6271442

Molecular Formula:: C10H12O5

Molecular Weight:: 212.2

MDL Number:: MFCD00002433

MOL File:: 573-11-5.mol

MSDS File:: SDS

Last updated:2026-05-28 05:40:49

Product description	Number	Pack Size	Price
2,3,4-Trimethoxybenzoic acid ≥98%	189790	25g	$34
2,3,4-Trimethoxybenzoic Acid >98.0%(GC)(T)	T1116	5g	$62
2,3,4-Trimethoxybenzoic Acid >98.0%(GC)(T)	T1116	25g	$172
2,3,4-Trimethoxybenzoic acid	FT71341	250g	$260
2,3,4-Trimethoxybenzoic acid	FT71341	500g	$430
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2,3,4-Trimethoxybenzoic acid Properties

Melting point	99-102 °C (lit.)
Boiling point	312.03°C (rough estimate)
Density	1.3006 (rough estimate)
refractive index	1.5140 (estimate)
storage temp.	Sealed in dry,Room Temperature
form	Crystalline Powder
pka	4.24±0.10(Predicted)
color	White to off-white
BRN	2696073
InChI	1S/C10H12O5/c1-13-7-5-4-6(10(11)12)8(14-2)9(7)15-3/h4-5H,1-3H3,(H,11,12)
InChIKey	HZNQSWJZTWOTKM-UHFFFAOYSA-N
SMILES	COc1ccc(C(O)=O)c(OC)c1OC
CAS DataBase Reference	573-11-5(CAS DataBase Reference)
NIST Chemistry Reference	2,3,4-Trimethoxybenzoic acid(573-11-5)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

PPE

Eyeshields, Gloves, type N95 (US)

Risk Statements

36/37/38

Safety Statements

24/25

WGK Germany

HS Code

29189900

Storage Class

11 - Combustible Solids

NFPA 704

	1
2		0

2,3,4-Trimethoxybenzoic acid price More Price(52)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	189790	2,3,4-Trimethoxybenzoic acid ≥98%	573-11-5	25g	$34	2023-06-20	Buy
TCI Chemical	T1116	2,3,4-Trimethoxybenzoic Acid >98.0%(GC)(T)	573-11-5	5g	$62	2026-04-30	Buy
TCI Chemical	T1116	2,3,4-Trimethoxybenzoic Acid >98.0%(GC)(T)	573-11-5	25g	$172	2026-04-30	Buy
Biosynth	FT71341	2,3,4-Trimethoxybenzoic acid	573-11-5	250g	$260	2026-06-04	Buy
Biosynth	FT71341	2,3,4-Trimethoxybenzoic acid	573-11-5	500g	$430	2026-06-04	Buy

Product number	Packaging	Price	Buy
189790	25g	$34	Buy
T1116	5g	$62	Buy
T1116	25g	$172	Buy
FT71341	250g	$260	Buy
FT71341	500g	$430	Buy

2,3,4-Trimethoxybenzoic acid Chemical Properties,Uses,Production

Chemical Properties

WHITE TO OFF-WHITE CRYSTALLINE POWDER

Uses

2,3,4-Trimethoxybenzoic acid was used in the synthesis of tropoloisoquinoline alkaloid pareitropone. It was also used in the synthesis of isomeric tris(pyrogallol) derivatives and naphthoic acid.

Synthesis

2103-57-3

573-11-5

General procedure for the synthesis of 2,3,4-trimethoxybenzoic acid from 2,3,4-trimethoxybenzaldehyde: To a stirred solution of 2,3,4-trimethoxybenzaldehyde (24.4 g, 124.4 mmol) in methanol (200 mL) was added an aqueous 50% potassium hydroxide solution (KOH, 22.4 g). The mixture was then heated to reflux. A 30% hydrogen peroxide solution (180 mL) was added dropwise over 30 minutes and the mixture was continued to reflux for 8 hours. After the oxidation reaction was complete, the reaction mixture was cooled and sodium bisulfite (NaHSO3) was added. Methanol was removed by distillation under reduced pressure and the resulting solution was acidified to acidity with concentrated hydrochloric acid. The precipitated 2,3,4-trimethoxybenzoic acid (25.0 g, 95% yield) was collected by filtration.

References

[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 9, p. 2671 - 2677
[2] Tetrahedron Letters, 2008, vol. 49, # 6, p. 1083 - 1086
[3] Helvetica Chimica Acta, 1924, vol. 7, p. 362
[4] Synthetic Communications, 2006, vol. 36, # 5, p. 679 - 683

2,3,4-Trimethoxybenzoic acid Preparation Products And Raw materials

Raw materials

2,3,4-Trimethoxybenzaldehyde Hydrogen peroxide Methanol Potassium hydroxide Water

Preparation Products

1,3,5,6-Tetramethoxy-9H-xanthen-9-one

2,3,4-Trimethoxybenzoic acid Suppliers

Global( 271)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21533	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114	sales@amoychem.com	China	6339	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
Zhengzhou Alfa Chemical Co.,Ltd	+86-18530059196	sale04@alfachem.cn	China	9628	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17339	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-17392587031	1059@dideu.com	China	9984	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58
CD Chemical Group Limited	+86-13651442114	info@codchem.com	China	17253	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Xiamen AmoyChem Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Alfa Chemical Co.,Ltd	58
SIMAGCHEM CORP	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
CD Chemical Group Limited	58

View Lastest Price from 2,3,4-Trimethoxybenzoic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-06-20	2,3,4-Trimethoxybenzoic acid 573-11-5	$1.00	1kg	98%min	20tons	Hebei Yanxi Chemical Co., Ltd.
2025-05-23	2,3,4-Trimethoxybenzoic acid 573-11-5	$10.00	1kg	99%	20 ton	Hebei Zhuanglai Chemical Trading Co Ltd
2019-07-12	2,3,4-Trimethoxybenzoic acid 573-11-5	$1.00	1KG	99%	1ton	Career Henan Chemical Co

2,3,4-Trimethoxybenzoic acid
573-11-5
$1.00
98%min
Hebei Yanxi Chemical Co., Ltd.

2,3,4-Trimethoxybenzoic acid
573-11-5
$10.00
99%
Hebei Zhuanglai Chemical Trading Co Ltd

2,3,4-Trimethoxybenzoic acid
573-11-5
$1.00
99%
Career Henan Chemical Co

2,3,4-Trimethoxybenzoic acid Spectrum

2,3,4-Trimethoxybenzoic acid(573-11-5)MS 2,3,4-Trimethoxybenzoic acid(573-11-5)¹HNMR 2,3,4-Trimethoxybenzoic acid(573-11-5)¹³CNMR 2,3,4-Trimethoxybenzoic acid(573-11-5)IR1 2,3,4-Trimethoxybenzoic acid(573-11-5)IR2 2,3,4-Trimethoxybenzoic acid(573-11-5)Raman

573-11-5(2,3,4-Trimethoxybenzoic acid)Related Search:

Benzoic acid 4-Aminobenzoic acid Estradiol benzoate 1,2,3-Trimethoxybenzene Trimethoxysilane

3-Chloropropyltrimethoxysilane Vinyltrimethoxysilane Trimethoxypropylsilane 1,2,4-Trimethoxybenzene Trimetazidine N-oxide

3,4,5-Trimethoxy benzoic acid Anthranilic acid 2,4,6-Trimethoxybenzoic acid 2-(4-morpholinyl)ethyl ester Methyl 2-nitro-3,4,5-trimethoxybenzoate 2,4,5-Trimethoxybenzoic acid

2-Amino-3,4,5-trimethoxybenzoic acid methyl ester 3,4,5-Trimethoxybenzoyl chloride Trimebutine

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Benzoic acid, 2,3,4-trimethoxy- 2,3,4-TRIMETHOXYBENZOIC ACID AKOS 214-77 LABOTEST-BB LT00454915 RARECHEM AL BO 0027 2,3,4-TRIMETHOXYBENZOIC ACID, 98+% 2,3,4-Trimethoxybenzoic 2,3,4-TRIMETHOXYBENZOIC ACID 99% 2,3,4-trimethoxybenzoate 2,3,4-TriMethoxybenzoic acid, 98+% 5GR Trimetazidine Impurity L Trimetazidine Impurity 4 Trimetazidine Impurity 19 573-11-5 Organic Building Blocks CARBOXYLIC ACID ARYL ACID Carboxylic Acids Carbonyl Compounds C10 Building Blocks Carbonyl Compounds Carboxylic Acids FINE Chemical & INTERMEDIATES C10 Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Organic acids