2-Bromo-5-methylbenzoic acid
- CAS No.
- 6967-82-4
- Chemical Name:
- 2-Bromo-5-methylbenzoic acid
- Synonyms
- NSC20686;Fluralaner-031;6-Bromo-m-toluic Acid;Fluralaner Impurity 52;2-Bromo-5-methylbenzoicaci;2-Bromo-5-methylbenzoic acid;Benzoic acid,2-bromo-5-methyl-;2-Bromo-5-methylbenzoicacid,98%;2-Phenyl-5-Methylcarboxylic acid;2-Bromo-5-methylbenzoic Acid >
- CBNumber:
- CB6342232
- Molecular Formula:
- C8H7BrO2
- Molecular Weight:
- 215.04
- MDL Number:
- MFCD00079722
- MOL File:
- 6967-82-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 136-140 °C |
|---|---|
| Boiling point | 311.6±30.0 °C(Predicted) |
| Density | 1.599±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 2.92±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C8H7BrO2/c1-5-2-3-7(9)6(4-5)8(10)11/h2-4H,1H3,(H,10,11) |
| InChIKey | ZXMISUUIYPFORW-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC(C)=CC=C1Br |
| CAS DataBase Reference | 6967-82-4(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H302-H335 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39-37 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
2-Bromo-5-methylbenzoic acid price More Price(80)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 716413 | 2-Bromo-5-methylbenzoic acid 97% | 6967-82-4 | 1g | $55.9 | 2026-04-30 | Buy |
| TCI Chemical | B4145 | 2-Bromo-5-methylbenzoic Acid >98.0%(GC)(T) | 6967-82-4 | 5g | $22 | 2026-04-30 | Buy |
| TCI Chemical | B4145 | 2-Bromo-5-methylbenzoic Acid >98.0%(GC)(T) | 6967-82-4 | 25g | $88 | 2026-04-30 | Buy |
| Usbiological | 261983 | 2-Bromo-5-methylbenzoic acid Asreported | 6967-82-4 | 1g | $329 | 2026-06-03 | Buy |
| Usbiological | 261983 | 2-Bromo-5-methylbenzoic acid Asreported | 6967-82-4 | 2g | $438 | 2026-06-03 | Buy |
2-Bromo-5-methylbenzoic acid Chemical Properties, Uses, Production
Chemical Properties
Off-white powder
Synthesis
2941-78-8
6967-82-4
The general procedure for the synthesis of 2-bromo-5-methylbenzoic acid from 2-amino-5-methylbenzoic acid was as follows: CuSO4-5H2O (2.82 g, 11.3 mmol), NaBr (2.31 g, 22.4 mmol), and copper scrapings (1.50 g, 23.6 mmol) were boiled in 15 mL of 47% hydrobromic acid until the solution became colorless. Under heating conditions, 5-methyl-phthalamic acid (5.00 g, 33.1 mmol) was dissolved in a solvent mixture of 11.3 mL of 47% aqueous hydrobromic acid and 28 mL of water. The solution was slowly added to the above CuBr solution at 100°C. The temperature of the reaction mixture was maintained at 90-95°C and 25 mL of aqueous solution of NaNO2 (4.53 g, 65.7 mmol) was slowly added with stirring. Upon completion of the reaction, the precipitated acid was collected by diafiltration, washed with 10% aqueous hydrobromic acid and reprecipitated by adding concentrated hydrochloric acid to the alkaline solution. The crude product was treated by activated charcoal and recrystallized from water three times to give 4.00 g (18.6 mmol, 56% yield) of white crystals with melting point of 137-139°C (literature value: 137.6-139°C). The product was analyzed by IR, 1H NMR, 13C NMR and mass spectrometry to confirm the structure, and the results of elemental analyses were consistent with the theoretical values.
References
[1] Phosphorus, Sulfur and Silicon and the Related Elements, 2015, vol. 190, # 12, p. 2142 - 2153
[2] Journal of Organic Chemistry, 1960, vol. 25, p. 1016 - 1020
2-Bromo-5-methylbenzoic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xinyi Kangda Biological Technology Co., Ltd. | 16503038585 | xinyikangda@163.com | China | 610 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
View Latest Price from 2-Bromo-5-methylbenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-08-06 | 2-BROMO-5-METHYLBENZOIC ACID
6967-82-4
|
$1.00 | 1KG | 98% | 150KG | Career Henan Chemical Co |
-
- 2-BROMO-5-METHYLBENZOIC ACID
6967-82-4
- $1.00
- 98%
- Career Henan Chemical Co
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