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ChemicalBook >> CAS DataBase List >>1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr

1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr

1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr Structure
1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr structure
CAS No.
59839-23-5
Chemical Name:
1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr
Synonyms
RMA-192;1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr;1,2,3,4-tetrahydroisoquinolin-6-ol, HBr salt;6-HYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE HBR;1,2,3,4-Tetrahydro-iso-6-hydroxy-quinoline HBr;1,2,3,4-Tetrahydro iso-6-hydroxy-quinoline HBr;1,2,3,4-Tetrahydroisoquinolin-6-olhydrobrimide;l,2,3,4-Tetrahydro-6-isoquinolinol Hydrobromide;1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HYDROBROMIDE;6-Isoquinolinol,1,2,3,4-tetrahydro-,hydrobromide
CBNumber:
CB6849403
Molecular Formula:
C9H12BrNO
Molecular Weight:
230.10168
MDL Number:
MFCD08437641
MOL File:
59839-23-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:26
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1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr Properties

Melting point 196.7-197.8℃
storage temp. Inert atmosphere,Room Temperature
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
Hazard Codes  Xn
Risk Statements  22
HS Code  2933491090

1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr price More Price(54)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 62445 6-HYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE HBR 97% 59839-23-5 0.25G $74 2026-04-30 Buy
AstaTech 62445 6-HYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE HBR 97% 59839-23-5 1G $135 2026-04-30 Buy
AstaTech 62445 6-HYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE HBR 97% 59839-23-5 5G $483 2026-04-30 Buy
Activate Scientific AS42844-B 1,2,3,4-Tetrahydro-isoquinolin-6-ol hydrobromide 95% 59839-23-5 1g $239 2026-06-04 Buy
Activate Scientific AS42844-B 1,2,3,4-Tetrahydro-isoquinolin-6-ol hydrobromide 95% 59839-23-5 5g $623 2026-06-04 Buy
Product number Packaging Price Buy
62445 0.25G $74 Buy
62445 1G $135 Buy
62445 5G $483 Buy
AS42844-B 1g $239 Buy
AS42844-B 5g $623 Buy

1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr Chemical Properties, Uses, Production

Uses

1,2,3,4-Tetrahydro-6-isoquinolin-6-ol Hydrobromide is a chemical reagent used in the organic synthesis. Used in the preparation of androgen receptor modulators (SARMs) as well as steroidmimetic and chimeric microtubule disruptors.

Synthesis

6-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE

42923-77-3

1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR

59839-23-5

General procedure for the synthesis of 1,2,3,4-tetrahydroisoquinolin-6-ol hydrobromide from 6-methoxy-1,2,3,4-tetrahydroisoquinoline: 6-methoxy-1,2,3,4-tetrahydroisoquinoline (2.12 g, 13.0 mmol) was dissolved in 48% aqueous hydrobromic acid. The reaction mixture was stirred at 120°C for 3 hours. After completion of the reaction, the solvent was removed by vacuum concentration. The obtained residue was suspended in ethyl acetate and the solvent was evaporated again to afford 1,2,3,4-tetrahydroisoquinolin-6-ol hydrobromide (2.99 g, 95% yield) as a reddish brown solid. The product was characterized by 1H NMR (300 MHz, D2O): δ 7.10 (d, J = 8.4 Hz, 1H), 6.82-6.75 (m, 2H), 4.28 (s, 2H), 3.48 (t, J = 6.3 Hz, 2H), 3.05 (t, J = 6.3 Hz, 2H).

References

[1] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 4, p. 789 - 801
[2] Journal of Medicinal Chemistry, 1987, vol. 30, # 12, p. 2208 - 2216
[3] Patent: US6562828, 2003, B1
[4] Patent: US5936089, 1999, A
[5] Patent: WO2007/146122, 2007, A2. Location in patent: Page/Page column 42

1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr Preparation Products And Raw materials

Raw materials

6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride 6-Methoxy-1,2,3,4-tetrahydro-isoquinoline Hydrogen bromide Water

Preparation Products

tert-Butyl 6-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate

1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr Suppliers

Global Suppliers ( 64)
Supplier Tel Email Country ProdList Advantage
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Modachem Shanghai Co., Ltd +86 (0)21 51320687 51371369 1744605818 China 1576 58
Shanghai PharmOrgsyn Technology Co., LTD. 021-+86-021-38228826 sales@pharmorgsyn.cn China 250 58
JW & Y Pharmlab Co., Ltd. 021-64340559 xinyu_shi@jwypharmlab.com.cn China 11999 58
Wuhan Chemwish Technology Co.， Ltd 027-67849912 sales@chemwish.com China 9144 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Shanghai Ennopharm Co., Ltd. 65
T&W GROUP 58
Shanghai Raise Chemical Technology Co.,Ltd 55
Modachem Shanghai Co., Ltd 58
Shanghai PharmOrgsyn Technology Co., LTD. 58
JW & Y Pharmlab Co., Ltd. 58
Wuhan Chemwish Technology Co.， Ltd 60
Amadis Chemical Company Limited 58

View Latest Price from 1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR pictures 2020-01-13 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR
59839-23-5
 $6.68 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co

1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr Spectrum

1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR(59839-23-5)1HNMR

59839-23-5 (1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr) Related Search:

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1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HYDROBROMIDE 1,2,3,4-Tetrahydroisoquinolin-6-olhydrobrimide l,2,3,4-Tetrahydro-6-isoquinolinol Hydrobromide 6-HYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE HBR 1,2,3,4-tetrahydro-6-hydroxy-isoquinoline-hydrobroMide 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline hydrobromide 1,2,3,4-Tetrahydro iso-6-hydroxy-quinoline HBr 1,2,3,4-Tetrahydro-iso-6-hydroxy-quinoline HBr 6-Isoquinolinol,1,2,3,4-tetrahydro-,hydrobromide 1,2,3,4-Tetrahydro-6-isoquinolinol (hydrobromide) 1,2,3,4-tetrahydroisoquinolin-6-ol, HBr salt 1,2,3,4-tetrahydroisoquinolin-6-ol hydrobromide (1:1) RMA-192 1,2,3,4-Tetrahydro-isoquinolin-6-ol HBr 59839-23-5 C9H11NOHBr C9H11NOBrH Quinoline&Isoquinoline