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2,5-Dihydroxybenzaldehyde

CAS No.
1194-98-5
Chemical Name:
2,5-Dihydroxybenzaldehyde
Synonyms
Gentisate aldehyde;GENTISALDEHYDE;NSC 72387;GENTISINALDEHYDE;Cyanohydroquinone;GENTISIC ALDEHYDE;ForMylhydroquinone;2,5-Dihydroxybenzald;5-HYDROXYSALICYLALDEHYDE;2,5-DIHYDROXYBENZALDEHYDE
CBNumber:
CB7146305
Molecular Formula:
C7H6O3
Molecular Weight:
138.12
MDL Number:
MFCD00003333
MOL File:
1194-98-5.mol
MSDS File:
SDS
Last updated:2026-07-20 23:19:27

2,5-Dihydroxybenzaldehyde Properties

Melting point 97-99 °C (lit.)
Boiling point 213.5°C (rough estimate)
Density 1.2667 (rough estimate)
refractive index 1.4797 (estimate)
storage temp. Store below +30°C.
solubility 13.8g/l soluble
pka 8.89±0.18(Predicted)
form Crystalline Powder
color Yellow to khaki-green
Water Solubility soluble
Sensitive Air Sensitive
BRN 1363961
InChI 1S/C7H6O3/c8-4-5-3-6(9)1-2-7(5)10/h1-4,9-10H
InChIKey CLFRCXCBWIQVRN-UHFFFAOYSA-N
SMILES Oc1ccc(O)c(C=O)c1
LogP 0.540
CAS DataBase Reference 1194-98-5(CAS DataBase Reference)
FDA UNII 0Q83HDS90W
NIST Chemistry Reference 2,5-Dihydroxybenzaldehyde(1194-98-5)
EPA Substance Registry System Benzaldehyde, 2,5-dihydroxy- (1194-98-5)
UNSPSC Code 12352114
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H317-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38-43
Safety Statements  26-36/37/39-37/39-26,37/39-36
WGK Germany  3
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  29124990
Storage Class 13 - Non Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
STOT SE 3
NFPA 704
0
2 0

2,5-Dihydroxybenzaldehyde price More Price(90)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D108200 2,5-Dihydroxybenzaldehyde 98% 1194-98-5 5g $183 2026-04-30 Buy
Sigma-Aldrich D108200 2,5-Dihydroxybenzaldehyde 98% 1194-98-5 25g $868 2026-04-30 Buy
TCI Chemical D0565 2,5-Dihydroxybenzaldehyde >98.0%(GC) 1194-98-5 1g $27 2026-04-30 Buy
TCI Chemical D0565 2,5-Dihydroxybenzaldehyde >98.0%(GC) 1194-98-5 5g $94 2026-04-30 Buy
Cayman Chemical 30268 2,5-Dihydroxybenzaldehyde ≥98% 1194-98-5 5g $95 2026-04-30 Buy
Product number Packaging Price Buy
D108200 5g $183 Buy
D108200 25g $868 Buy
D0565 1g $27 Buy
D0565 5g $94 Buy
30268 5g $95 Buy

2,5-Dihydroxybenzaldehyde Chemical Properties, Uses, Production

Description

2,5-Dihydroxybenzaldehyde is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activity.

Chemical Properties

yellow to khaki-green crystalline powder

Uses

2,5-Dihydroxybenzaldehyde (cas# 1194-98-5) is a compound useful in organic synthesis.

Application

2,5-Dihydroxybenzaldehyde is a is a natural phenol found in the heartwoods of Pseudolarix amabilis, it is a tyrosine kinase inhibitor. 2,5-Dihydroxybenzaldehyde has antimicrobial activity and is mostly used in experimental studies for the preparation of Schiff base derivatives and bioanodes for glucose fuel cells.

Preparation

Add 80 mmol of dry paraformaldehyde to a mixture of 12 mmol of the phenol derivative and 2.5 mmol of MgO nanocrystalline (0.1 g). Expose the resulting mixture under microwave irradiation with a power of 650 W. Monitor the progress of the reaction by thin layer chromatography (TLC) developed by n-hexane : ethyl acetate (8 : 2). Add 100 mL of sulfuric acid (15% w/w) to the reaction mixture and heated at 50 °C for 15 min. Cool the reaction mixture to room temperature. Extract the product by dichloromethane (2 x 50 mL). Dry the organic layer over anhydrous magnesium sulphate. Evaporate the solution resulting from filtration to obtain the crude product. Purify the other product by column chromatography using n-hexane : ethyl acetate (95 : 5 to 70 : 30).
synthesis of 2,5-Dihydroxybenzaldehyde

Definition

ChEBI: 2,5-dihydroxybenzaldehyde is a dihydroxybenzaldehyde carrying hydroxy groups at positions 2 and 5. It has a role as a Penicillium metabolite, a mouse metabolite and a human metabolite.

201230-82-2
23030-43-5
1194-98-5
Synthesis of 2,5-Dihydroxybenzaldehyde from carbon monoxide and 1,4-Dihydroxy-2-iodobenzene
Global Suppliers ( 517)
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Jiangxi Jingyang Chemical Products Co., LTD 0798-15170312128 15170312128 1436027029@qq.com China 16 58
Xi'an Pure&True New Materials Co., Ltd. 18991218082 13572462239 hongyan.zhao@xianpt.com China 120 58
Shanghai Daken Advanced Materials Co.,Ltd 18239137209 info@dakenchem.com China 423 58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd. 15995069468 15995069468 3398435160@qq.com China 300 58
Dancheng Huatai Biotechnology Co., Ltd. 13482210809 13482210809 hli@3wpharm.com China 357 58
Changzhou Xuanming Chemical 85525329 15961429598 2476433557@qq.com China 499 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61

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View Latest Price from 2,5-Dihydroxybenzaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,5-Dihydroxybenzaldehyde pictures 2026-09-19 2,5-Dihydroxybenzaldehyde
1194-98-5
0.99 RongNa Biotechnology Co.,Ltd
2,5-Dihydroxybenzaldehyde pictures 2026-09-18 2,5-Dihydroxybenzaldehyde
1194-98-5
$666.00-999.00 1ton 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
2,5-Dihydroxybenzaldehyde pictures 2026-08-18 2,5-Dihydroxybenzaldehyde
1194-98-5
$190.00 1KG 99.00% 1000kg/month Shanghai Daken Advanced Materials Co.,Ltd
GENTISIC ALDEHYDE GENTISINALDEHYDE 5-HYDROXYSALICYLALDEHYDE 2,5-DIHYDROXYBENZALDEHYDE Benzaldehyde, 2,5-dihydroxy- 2,5-Dihydroxybenzaldehyde, 98+% 2,5-Dihydroxybenzaldchyde Gentisate aldehyde 2,5-DIHYDROXYBENZALDEHYDE 98.5% Cyanohydroquinone 2,5-Dihydroxybenzaldehyde,99% 2,5-Dihydroxybenzald ForMylhydroquinone NSC 72387 Gentisaldehyde, 2-Formylhydroquinone, 2-Formylbenzene-1,4-diol 2,5-Dihydroxybenzaldehyde, 99% 5GR 2,5-Dihydroxybenzaldehyde SynonyMs Gentisaldehyde 2,5-Dihydroxybenzaldehyde Vetec(TM) reagent grade, 98% 2,5-Dihydroxybenzaldehyde, 98% or higher by HPLC 2,5-Dihydroxybenzaldehyde MSDS Free sample 2,5-dihydroxybenzaldehyde COA TDS MSDS free sample 2,5-Dihydroxybenzaldehyde 2913000090 10% UN3335 9 III 2912499090 10% 2,5-Dihydroxybenzaldehyde IN STOCK 2,5-Dihydroxybenzaldehyde Factory 2,5-Dihydroxybenzaldehyde COA TDS MSDS 2,5-Dihydroxybenzaldehyde > 2,5-Dihydroxybenzaldehyde,>95% 2,5-Dihydroxybenzaldehyde,NA Dihydroxybenzaldehyde2,5- 2,5-Dihydroxybenzaldehyde, 10 mM in DMSO GENTISALDEHYDE 1194-98-5 194-98-5 ALDEHYDE Aldehydes Building Blocks Carbonyl Compounds C7 Organic Building Blocks 1 Aromatic Aldehydes & Derivatives (substituted) Aromatics Aldehydes Phenyls & Phenyl-Het Benzaldehyde Phenyls & Phenyl-Het 1194-98-5