ChemicalBook >> CAS DataBase List >>6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE

6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE

CAS No.
5426-59-5
Chemical Name:
6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE
Synonyms
6-broMo-2-Methylquinazolin-4-ol;6-bromo-2-methyl-1H-quinazolin-4-one;6-bromo-2-methyl-4(3H)-Quinazolinone;6-bromo-2-methylquinazolin-4(1H)-one;6-bromo-2-methyl-3H-quinazolin-4-one;4(3H)-Quinazolinone, 6-bromo-2-methyl-;4(1H)-Quinazolinone, 6-bromo-2-methyl-;6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE;6-bromo-2-methylquinazolin-4(3H)-one(SALTDATA: FREE)
CBNumber:
CB71502674
Molecular Formula:
C9H7BrN2O
Molecular Weight:
239.07
MDL Number:
MFCD00548197
MOL File:
5426-59-5.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:49

6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE Properties

Melting point 298 °C
Boiling point 372.6±44.0 °C(Predicted)
Density 1.72±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 1.96±0.20(Predicted)
Appearance Off-white to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Risk Statements  22
Safety Statements  36/37
HS Code  29339900

6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B697670 6-Bromo-2-methylquinazolin-4(3H)-one 5426-59-5 100mg $45 2021-12-16 Buy
TRC B697670 6-Bromo-2-methylquinazolin-4(3H)-one 5426-59-5 250mg $55 2021-12-16 Buy
TRC B697670 6-Bromo-2-methylquinazolin-4(3H)-one 5426-59-5 500mg $65 2021-12-16 Buy
Frontier Specialty Chemicals JK231259 6-Bromo-2-methylquinazolin-4(3H)-one 97% 5426-59-5 1g $272 2021-12-16 Buy
Matrix Scientific 072338 6-Bromo-2-methylquinazolin-4(3H)-one 95+% 5426-59-5 1g $347 2021-12-16 Buy
Product number Packaging Price Buy
B697670 100mg $45 Buy
B697670 250mg $55 Buy
B697670 500mg $65 Buy
JK231259 1g $272 Buy
072338 1g $347 Buy

6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE Chemical Properties,Uses,Production

Chemical Properties

Light yellow solid

Synthesis

Acetic anhydride

108-24-7

2-Amino-5-bromobenzoic acid

5794-88-7

6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE

5426-59-5

The general procedure for the synthesis of 6-bromo-2-methylquinazolin-4(3H)-one from ethanoic anhydride and 2-amino-5-bromobenzoic acid was as follows: first, 2-amino-5-bromobenzoic acid was refluxed for 1 h in liquid ammonia (10 mL/g). Subsequently, the reaction solution was concentrated to a smaller volume and the residue was mixed with acetic anhydride (2 mL/g) and refluxing was continued for 4 hours. Upon completion of the reaction, water was added to the mixture and boiled for 30 minutes, followed by dropwise addition of 20% sodium hydroxide solution until a clarified solution was formed. Next, ammonium carbonate was added to the hot solution until a precipitate was formed. The mixture was allowed to stand at 4°C for 16 hours, after which the precipitate was collected by filtration, washed with water and finally dried under vacuum to give the target product in about 60% yield.

References

[1] Patent: US2009/69320, 2009, A1. Location in patent: Page/Page column 76
[2] Journal of the American Chemical Society, 1906, vol. 28, p. 101

64-17-5
16313-66-9
5426-59-5
Synthesis of 6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE from Ethanol and 2-AMINO-5-BROMOBENZAMIDE
Global( 86)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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Alchem Pharmtech,Inc.
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career henan chemical co
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Dayang Chem (Hangzhou) Co.,Ltd.
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HANGZHOU LEAP CHEM CO., LTD.
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Aromsyn Co., Ltd.
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View Lastest Price from 6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE pictures 2020-01-13 6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE
5426-59-5
US $6.68 / KG 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co

6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE Spectrum

6-BROMO-2-METHYL-3,4-DIHYDROQUINAZOLIN-4-ONE 6-bromo-2-methyl-1H-quinazolin-4-one 6-bromo-2-methylquinazolin-4(3H)-one(SALTDATA: FREE) 6-broMo-2-Methylquinazolin-4-ol 6-bromo-2-methylquinazolin-4(1H)-one 6-bromo-2-methyl-4(3H)-Quinazolinone 4(1H)-Quinazolinone, 6-bromo-2-methyl- 4(3H)-Quinazolinone, 6-bromo-2-methyl- 6-bromo-2-methyl-3H-quinazolin-4-one 5426-59-5