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2-Bromo-5-fluorobenzoic acid

2-Bromo-5-fluorobenzoic acid Structure
2-Bromo-5-fluorobenzoic acid structure
CAS No.
394-28-5
Chemical Name:
2-Bromo-5-fluorobenzoic acid
Synonyms
BUTTPARK 19\01-66;RARECHEM AL BO 0747;2-Bromo-5-fluorobenz;2-Bromo-5-Fluorobenzoic;2-BROMO-5-FLUOROBENZOIC ACID;2-bromo-5-fluorobenzoicacid,98%;Benzoic acid, 2-bromo-5-fluoro-;2-Bromo-5-fluorobenzoic Acid >2-Bromo-5-fluorobenzoic acid 98%;2-BroMo-5-fluorobenzoic Acid, 97+%
CBNumber:
CB7249219
Molecular Formula:
C7H4BrFO2
Molecular Weight:
219.01
MDL Number:
MFCD00142874
MOL File:
394-28-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:52
Product description Number Pack Size Price
2-Bromo-5-fluorobenzoic Acid >98.0%(GC)(T) B2722 5g $94
2-Bromo-5-fluorobenzoic Acid >98.0%(GC)(T) B2722 25g $308
2-Bromo-5-fluorobenzoic acid B691983 5g $75
2-Bromo-5-fluorobenzoic acid FB12070 100g $87.5
2-Bromo-5-fluorobenzoic acid 98% 001714 100g $59
More product size
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2-Bromo-5-fluorobenzoic acid Properties

Melting point 154-157 °C (lit.)
Boiling point 291.1±25.0 °C(Predicted)
Density 1.789±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
pka 2.51±0.10(Predicted)
form powder to crystal
color White to Almost white
BRN 2575978
InChI InChI=1S/C7H4BrFO2/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3H,(H,10,11)
InChIKey OQBMJMJZMDBQSM-UHFFFAOYSA-N
SMILES C(O)(=O)C1=CC(F)=CC=C1Br
CAS DataBase Reference 394-28-5(CAS DataBase Reference)
EPA Substance Registry System Benzoic acid, 2-bromo-5-fluoro- (394-28-5)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39-24/25
WGK Germany  3
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29163990
Storage Class 13 - Non Combustible Solids
NFPA 704
1
2 0

2-Bromo-5-fluorobenzoic acid price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B2722 2-Bromo-5-fluorobenzoic Acid >98.0%(GC)(T) 394-28-5 5g $94 2026-04-30 Buy
TCI Chemical B2722 2-Bromo-5-fluorobenzoic Acid >98.0%(GC)(T) 394-28-5 25g $308 2026-04-30 Buy
TRC B691983 2-Bromo-5-fluorobenzoic acid 394-28-5 5g $75 2021-12-16 Buy
Biosynth Carbosynth FB12070 2-Bromo-5-fluorobenzoic acid 394-28-5 100g $87.5 2021-12-16 Buy
Matrix Scientific 001714 2-Bromo-5-fluorobenzoic acid 98% 394-28-5 100g $59 2021-12-16 Buy
Product number Packaging Price Buy
B2722 5g $94 Buy
B2722 25g $308 Buy
B691983 5g $75 Buy
FB12070 100g $87.5 Buy
001714 100g $59 Buy

2-Bromo-5-fluorobenzoic acid Chemical Properties,Uses,Production

Uses

2-Bromo-5-fluorobenzoic acid, a common organic synthesis intermediate, is primarily used to synthesize target molecular structures by utilizing the bromine and fluorine atoms on the benzene ring. For example, the bromine atom can undergo Suzuki coupling to introduce an aromatic ring or alkyl chain; or it can be converted into boric acid or borate esters, leveraging the versatility of borate esters to synthesize complex molecules. The fluorine atom can also undergo a series of transformations, including aromatic nucleophilic substitution reactions. Finally, the carboxyl group on the benzene ring can be readily converted into amides, esters, viboramides, etc.

Chemical Properties

white to light yellow crystal powder

Synthesis

2-Bromo-5-fluorobenzoic acid is synthesized from 5-(2′-bromophenoxy)benzothiazole and 2,3,4,5,6-pentafluorobenzoyl chloride in three steps. The synthesis involves bromination of benzothiazole with NBS followed by reaction with 4-fluoroaniline to give the intermediate which is then reacted with pentafluorobenzoyl chloride.

References

[1] Patent: WO2005/56544, 2005, A1. Location in patent: Page/Page column 46

2-Bromo-5-fluorobenzoic acid Preparation Products And Raw materials

Raw materials

2-Bromo-5-fluorobenzyl alcohol 2-Bromo-5-fluorobenzaldehyde 2-Amino-5-fluorobenzoic acid Sodium nitrite Hydrogen bromide
Cuprous bromide

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Preparation Products

N-Benzyl-2-bromo-5-fluorobenzamide

2-Bromo-5-fluorobenzoic acid Suppliers

Global( 380)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29640 60
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Hi-Tech Chemistry Corp 		0519-86626038 yuhh@hitechem.com CHINA 810 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21590 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Speranza Chemical Co., Ltd. 		+86-86-075521030354 +8618688942810 sophieliu@speranzachem.com China 923 55
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 52513593@qq.com CHINA 2972 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Changzhou Ditong Chemical Co.,Ltd 		+86-0519-88298848 info@edengenechem.com China 2176 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Hi-Tech Chemistry Corp 		58
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
Speranza Chemical Co., Ltd. 		55
Nanjing Dolon Biotechnology Co.,Ltd. 		58
Accela ChemBio Inc. 		58
Changzhou Ditong Chemical Co.,Ltd 		58
Alchem Pharmtech,Inc. 		58

View Lastest Price from 2-Bromo-5-fluorobenzoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-5-fluorobenzoic acid pictures 2026-04-30 2-Bromo-5-fluorobenzoic acid
394-28-5
 US $120.00 / KG 1KG 98% 20 tons Speranza Chemical Co., Ltd.
2-Bromo-5-fluorobenzoic acid pictures 2026-02-02 2-Bromo-5-fluorobenzoic acid
394-28-5
 US $0.10 / KG 0.1KG 98% 200TONS Shaanxi Dideu Medichem Co. Ltd
2-Bromo-5-fluorobenzoic acid pictures 2024-04-15 2-Bromo-5-fluorobenzoic acid
394-28-5
 US $1.00-100.00 / mg 100mg 0.99 5ton/month ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD

2-Bromo-5-fluorobenzoic acid Spectrum

2-Bromo-5-fluorobenzoic acid(394-28-5)1HNMR2-Bromo-5-fluorobenzoic acid(394-28-5)19FNMR2-Bromo-5-fluorobenzoic acid(394-28-5)IR

394-28-5(2-Bromo-5-fluorobenzoic acid)Related Search:

METHYL 4-BROMO-3-FLUOROBENZOATE 98 2-nitro-4-Bromo-5-fluorobenzoic acid 2-Bromo-3,4,5,6-tetrafluorobenzoic acid METHYL 2-BROMO-5-FLUOROBENZOATE 2-BROMO-4,5-DIFLUOROBENZOIC ACID
3-Bromo-4-fluorobenzoic acid 98%,3-BROMO-4-FLUOROBENZOIC ACID 3-Bromo-2-fluorobenzoic acid 97%+,3-BROMO-2-FLUOROBENZOIC ACID 5-Bromo-2-fluorobenzoic acid 97%,5-Bromo-2-Fluorobenzoic Acid 2-Fluoro-5-Bromobenzoic Acid,5-BROMO-2-FLUOROBENZOIC ACID METHYL 3-BROMO-5-FLUOROBENZOATE METHYL 2-BROMO-4-FLUOROBENZOATE
3-BROMO-5-FLUOROBENZOIC ACID,5-BROMO-3-FLUOROBENZOIC ACID,5-Bromo-3-Fluorobenzoic Acid 3-Fluoro-5-Bromobenzoic Acid,3-Bromo-5-fluorobenzoic acid 98% 4-Bromo-3-fluorobenzoic acid, 98+%,4-BROMO-3-FLUOROBENZOIC ACID 2-AMINO-3,5-DIBROMO-6-FLUOROBENZOIC ACID 2-BROMO-3-FLUOROBENZOIC ACID,3-Fluoro-2-Bromo Benzoic Acid 2-Bromo-3-Fluorobenzoic Acid 4-BROMO-2-FLUOROBENZOIC ACID,4-Bromo-2-Fluorobenzoic Acid 2-Fluoro-4-Bromobenzoic Acid,4-Bromo-2-fluorobenzoic acid 98%
6-Bromo-2-Fluorobenzoic Acid,2-BROMO-6-FLUOROBENZOIC ACID,6-Bromo-2-Fluorobenzoic Acid 2-Fluoro-6-Bromobenzoic Acid 2-BROMO-4-FLUOROBENZOIC ACID 3-BROMO-4-FLUORO-BENZOIC ACID METHYL ESTER

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2-Bromine-5-Fluoride Benzoic Acids 2-Bromo-5-fluorobenz 2-bromo-5-fluorobenzoicacid,98% RARECHEM AL BO 0747 2-BroMo-5-fluorobenzoic Acid, 97+% BUTTPARK 19\01-66 2-BROMO-5-FLUOROBENZOIC ACID 2-Bromo-5-Fluorobenzoic 2-Bromo-5-fluorobenzoic acid 98% 2-Bromo-5-fluorobenzoic Acid > Benzoic acid, 2-bromo-5-fluoro- 2-Bromo-5-flu2-Bromo-5-fluorobenzoic acidorobenzoic acid 394-28-5 2-Bromo-5-fluorobenzoic acid 2-bromo-5-fluorobenzoic acid, 99%min 394-28-5 C6H3BrFCOOH C7 Carbonyl Compounds Carboxylic Acids Building Blocks Organic Building Blocks Benzoic acid series C7 Carbonyl Compounds Carboxylic Acids Bromine Compounds Fluorine Compounds intermediate Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Benzoic acid Miscellaneous Acids & Esters FINE Chemical & INTERMEDIATES blocks Bromides Carboxes FluoroCompounds Acids and Derivatives Halides Fluorin-contained Benzoic acid series john's