3-Carboxyphenylboronic acid pinacol ester
- CAS No.
- 269409-73-6
- Chemical Name:
- 3-Carboxyphenylboronic acid pinacol ester
- Synonyms
- 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOIC ACID;CAS:269409-73-6;2-dioxaborolan-2-yl)benzoic acid;Tranexamic Acid Impurity 28-13C2;3-Carboxyphenylboronic acid picol ester;3-CARBOXYPHENYLBORONIC ACID, PINACOL ESTER;3-Carboxybenzeneboronic acid, pinacol ester;3-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid;3-Carboxyphenylboronic acid, pinacol ester - [C2162];3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoicaci
- CBNumber:
- CB7265707
- Molecular Formula:
- C13H17BO4
- Molecular Weight:
- 248.08
- MDL Number:
- MFCD03411930
- MOL File:
- 269409-73-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 206-211 °C |
|---|---|
| Boiling point | 395.1±25.0 °C(Predicted) |
| Density | 1.15±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 4.20±0.10(Predicted) |
| form | Powder |
| color | White |
| Water Solubility | Insoluble |
| InChI | InChI=1S/C13H17BO4/c1-12(2)13(3,4)18-14(17-12)10-7-5-6-9(8-10)11(15)16/h5-8H,1-4H3,(H,15,16) |
| InChIKey | OPWAPCOSDAFWFB-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=CC(B2OC(C)(C)C(C)(C)O2)=C1 |
| CAS DataBase Reference | 269409-73-6(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H227 | |||||||||
| Precautionary statements | P210-P280-P264-P301+P312-P403+P235-P501A | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | No | |||||||||
| HS Code | 29310099 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
3-Carboxyphenylboronic acid pinacol ester price More Price(62)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 574694 | 3-Carboxyphenylboronic acid pinacol ester 97% | 269409-73-6 | 1g | $36.7 | 2026-04-30 | Buy |
| TCI Chemical | T3162 | 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid >98.0%(GC)(T) | 269409-73-6 | 1g | $23 | 2026-04-30 | Buy |
| TCI Chemical | T3162 | 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid >98.0%(GC)(T) | 269409-73-6 | 5g | $59 | 2026-04-30 | Buy |
| Strem Chemicals | 05-1036 | 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid, min. 97% min.97% | 269409-73-6 | 1g | $74 | 2026-04-30 | Buy |
| Strem Chemicals | 05-1036 | 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid, min. 97% min.97% | 269409-73-6 | 5g | $290 | 2026-04-30 | Buy |
3-Carboxyphenylboronic acid pinacol ester Chemical Properties, Uses, Production
Chemical Properties
almost white to light beige crystalline powder
Uses
3-Carboxyphenylboronic Acid Pinacol Ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
585-76-2
73183-34-3
269409-73-6
After degassing into 1,4-dioxane (0.1 M) under nitrogen atmosphere, m-bromobenzoic acid (1 eq.), pinacol ester of bisboronic acid (1.5 eq.) and potassium acetate (4.4 eq.) were added. The mixture was degassed again followed by the addition of PdCl2 (dppf) (5%). The resulting solution was heated to 110°C for overnight reaction. Upon completion of the reaction, the solvent was removed under vacuum to give a dark colloidal residue. This residue was dissolved in ethyl acetate and water to separate the organic layer. The aqueous phase was further extracted with ethyl acetate (2×). The combined organic layers were washed with 2M HCl, dried over MgSO4 and concentrated in vacuum to give a dark brown product. To purify the product, column chromatography (petroleum ether/ethyl acetate elution) was used. The 3-carboxyphenylboronic acid pinacol ester prepared by Suzuki coupling reaction was a light brown solid in 89% yield.1H NMR (400 MHz, CDCl3) δ 8.57 (s, 1H), 8.19 (ddd, J = 21.9, 1.18, 10.1 Hz, 1H), 8.09-7.98 (m, 1H), 7.57-7.38 (m, 1H), 1.37 (m, 1H), 7.57-7.38 (m, 1H). 1H), 1.37 (s, 12H).13C NMR (101 MHz, CDCl3) δ 171.66, 139.98, 136.60, 132.84, 128.71, 127.93, 84.21, 24.89.LCMS (ESI) m/z 249.2 [M + H]+.
References
[1] Patent: WO2016/198507, 2016, A1. Location in patent: Page/Page column 39; 49
3-Carboxyphenylboronic acid pinacol ester Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Boron Technology (Beijing) Co., Ltd. | 010-15313962280 15313962280 | 3004509780@qq.com | China | 824 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
View Latest Price from 3-Carboxyphenylboronic acid pinacol ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-13 | 3-Carboxyphenylboronic acid pinacol ester
269409-73-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 3-Carboxyphenylboronic acid pinacol ester
269409-73-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | 3-Carboxyphenylboronic acid pinacol ester
269409-73-6
|
$8.00 | 1KG | 99% | 10tons | Career Henan Chemical Co |
-
- 3-Carboxyphenylboronic acid pinacol ester
269409-73-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-Carboxyphenylboronic acid pinacol ester
269409-73-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-Carboxyphenylboronic acid pinacol ester
269409-73-6
- $8.00
- 99%
- Career Henan Chemical Co
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