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Ethylenebis(oxyethylenenitrilo)tetraacetic acid

Ethylenebis(oxyethylenenitrilo)tetraacetic acid structure

CAS No.: 67-42-5

Chemical Name:: Ethylenebis(oxyethylenenitrilo)tetraacetic acid

Synonyms: EGTA;EGTAZIC ACID;1,2-bis(2-dicarboxymethylaminoethoxy)ethane;ethylenedioxybis(ethyleneamino)tetraaceticacid;AEGT;GEDTA;GIETA;ebonta;Egtazic;CHEL-DE

CBNumber:: CB7671001

Molecular Formula:: C14H24N2O10

Molecular Weight:: 380.35

MDL Number:: MFCD00004291

MOL File:: 67-42-5.mol

MSDS File:: SDS

Last updated:2025-12-15 14:23:52

Product description	Number	Pack Size	Price
OmniPur EGTA -CAS 67-42-5 - Calbiochem	4100-OP	50g	$260
EGTA, Molecular Biology Grade - CAS 67-42-5 - Calbiochem	324626	25g	$201
Titriplex® VI for analysis	1.08435	25g	$453
Titriplex® VI for analysis	1.08435	100g	$648
Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid BioUltra, for molecular biology, ≥99.0% (T)	03777	10g	$213
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Ethylenebis(oxyethylenenitrilo)tetraacetic acid Properties

Melting point	241 °C (dec.)(lit.)
Boiling point	507.99°C (rough estimate)
bulk density	450kg/m3
Density	1.2838 (rough estimate)
refractive index	1.4590 (estimate)
storage temp.	room temp
solubility	0.1 M NaOH: 0.1 M at 20 °C, clear, colorless
form	Crystalline Powder
pka	1.47±0.10(Predicted)
color	White
biological source	synthetic (organic)
Water Solubility	slightly soluble
Merck	14,3529
BRN	1717370
CAS DataBase Reference	67-42-5(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	526U7A2651
EPA Substance Registry System	Ethylenebis(oxyethylenenitrilo)tetraacetic acid (67-42-5)
Absorption	cut-off at 263nm in 1 M NaOH at 0.1M
UNSPSC Code	12352106
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H303

Precautionary statements

P270-P301+P312-P403-P501c

Hazard Codes

Risk Statements

36/37/38

Safety Statements

24/25-36-26

WGK Germany

RTECS

AH3760000

TSCA

Yes

HS Code

29225000

Toxicity

LD50 orally in Rabbit: 3587 mg/kg

NFPA 704

	1
1		0

Ethylenebis(oxyethylenenitrilo)tetraacetic acid price More Price(53)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	4100-OP	OmniPur EGTA -CAS 67-42-5 - Calbiochem	67-42-5	50g	$260	2025-07-31	Buy
Sigma-Aldrich	324626	EGTA, Molecular Biology Grade - CAS 67-42-5 - Calbiochem	67-42-5	25g	$201	2025-07-31	Buy
Sigma-Aldrich	1.08435	Titriplex® VI for analysis	67-42-5	25g	$453	2025-07-31	Buy
Sigma-Aldrich	1.08435	Titriplex® VI for analysis	67-42-5	100g	$648	2025-07-31	Buy
Sigma-Aldrich	03777	Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid BioUltra, for molecular biology, ≥99.0% (T)	67-42-5	10g	$213	2025-07-31	Buy

Product number	Packaging	Price	Buy
4100-OP	50g	$260	Buy
324626	25g	$201	Buy
1.08435	25g	$453	Buy
1.08435	100g	$648	Buy
03777	10g	$213	Buy

Ethylenebis(oxyethylenenitrilo)tetraacetic acid Chemical Properties,Uses,Production

Description

Ethylenebis(oxyethylenenitrilo)tetraacetic acid is also named as Egtazic acid. It works as a chelating agent for the determination of calcium in the presence of magnesium.

Chemical Properties

White to slightly off-white powder

Uses

Pharmaceutic aid. EGTA.

Uses

Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid is a chelating agent used for making complexes, especially for calcium ions, which help to determine calcium in the presence of magnesium. It can be used experimentally for treating animals possessing cerium poisoning. It is useful in the separation of thorium from monazite. It also acts as a buffer and is used in protein purification.

Uses

A chelating agent useful for the determination of calcium in the presence of magnesium.

Definition

ChEBI: A diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.

reaction suitability

reagent type: chelator

Biological Activity

Calcium chelator; protects against cell death caused by nitric oxide-induced calcium influx into nerve cells.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. See also GLYCOL ETHERS.

storage

Room temperature

Purification Methods

Dissolve EGTA in aqueous NaOH, precipitate it by adding aqueous HCl, wash it with water and dry at 100o in vacuo.[Beilstein 4 IV 217.]

Ethylenebis(oxyethylenenitrilo)tetraacetic acid Preparation Products And Raw materials

Raw materials

1,8-Diamino-3,6-dioxaoctane Chloroacetic acid

Preparation Products

Ethylenebis(oxyethylenenitrilo)tetraacetic acid Suppliers

Global( 589)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-17392712697	1022@dideu.com	China	3994	58
Wuhan Fortuna Chemical Co., Ltd	+86-027-59207850 +86-13986145403;	info@fortunachem.com	China	6000	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5249	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20134	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3692	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21610	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29843	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
Wuhan Fortuna Chemical Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58

View Lastest Price from Ethylenebis(oxyethylenenitrilo)tetraacetic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-17	Ethylenebis(oxyethylenenitrilo)tetraacetic acid 67-42-5			0.99		RongNa Biotechnology Co.,Ltd
2025-12-17	Ethylenebis(oxyethylenenitrilo)tetraacetic acid 67-42-5	US $0.00-0.00 / KG	1KG	99%	3500kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2025-12-15	EGTA 67-42-5	US $31.00 / mg		99.49%	10g	TargetMol Chemicals Inc.

Ethylenebis(oxyethylenenitrilo)tetraacetic acid
67-42-5
0.99
RongNa Biotechnology Co.,Ltd

Ethylenebis(oxyethylenenitrilo)tetraacetic acid
67-42-5
US $0.00-0.00 / KG
99%
WUHAN FORTUNA CHEMICAL CO., LTD

EGTA
67-42-5
US $31.00 / mg
99.49%
TargetMol Chemicals Inc.

Ethylenebis(oxyethylenenitrilo)tetraacetic acid Spectrum

Ethylenebis(oxyethylenenitrilo)tetraacetic acid(67-42-5)MS Ethylenebis(oxyethylenenitrilo)tetraacetic acid(67-42-5)¹HNMR Ethylenebis(oxyethylenenitrilo)tetraacetic acid(67-42-5)IR1 Ethylenebis(oxyethylenenitrilo)tetraacetic acid(67-42-5)IR2 Ethylenebis(oxyethylenenitrilo)tetraacetic acid(67-42-5)Raman

67-42-5(Ethylenebis(oxyethylenenitrilo)tetraacetic acid)Related Search:

ETHYLENE Ethyl ethoxyacetate Iminodiacetic acid Ethylene glycol 2-Butoxyethanol

2-Phenoxyethanol 2-Butoxyethyl acetate Ethylene carbonate Folic acid Ethyl 2-(Chlorosulfonyl)acetate

GLYCOFUROL POLY(ETHYLENE-CO-ACRYLIC ACID) Ethylenediamine-N,N'-diacetic acid Hyaluronic acid Stearic acid

2-(Vinyloxy)ethanol Citric acid ETHANE

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3,6-DIOXAOCTAMETHYLENEDINITRILOTETRAACETIC ACID 1,2-bis(2-dicarboxymethylaminoethoxy)ethane 12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-9-dioxa-3 6,9-Dioxa-3,12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)- 9-Dioxa-3,12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-6 ebonta ethylenedioxybis(ethyleneamino)tetraaceticacid ETHYLENE GLYCOL BIS-(BETA-AMINOETHYLETHER)-N,N,N',N'-TETRAACETIC Egtazic chel tm -de ETHYLENE GLYCOL-BIS(B-AMINOETHYL*ETHER)N ,N,N',N'-TE ETHYLENE GLYCOL-O,O'-BIS(2-AMINOETHYL)-N ,N,N',N'-T.ACET.AC ETHYLENE GLYCOL-O,O'-BIS(2-AMINOETHYL)-N ,N,N',N'-TETRAAC. IDRANAL VI R. G. ETHYLENE GLYCOL-O,O'-BIS(2-AMINOETHYL)-N ,N,N',N'-TETRAACET. EGTA MOLECULAR BIOLOGY REAGENT Egta(EthyleneGlycolBis-(AminoethylEther)TetraceticAcid) 1,2-Bis-(2-aminoethoxyethane)-N,N,N',N'-tetraaceti ETHYLENEGLYCOL-bis-(AMINOETHYLETHER)-TETRAACETIC ACID REAGENT (EGTA) ETHYLENE GLYCOL-O,-O'-bis(2-AMINOETHYL) N,N,N,N-TETRAACETIC ACID extrapure ChelTM-DE, EGTA, Egtazic acid, Ethylene-bis(oxyethylenenitrilo)tetraacetic acid, Glycol ether diamine tetraacetic acid ETHYLENEGLYCOLBIS(2-AMINOETHYLETHER)-N,N,NNTETRAACETICACID,HIGHPURITY ETHYLENEGLYCOLBIS(BETA-AMINOETHYLETHER)TETRAACETICACID ETHYLENE GLYCOL-O,O''-BIS(2-AMINOSTHYL)-N,N,N'',N''-TETRAACETIC ACID ETHYLENE GLYCOL BIS(2-AMINOETHYL ETHER)TETRAACETIC ACID (EGTA) EGTA MOLECULAR BIOLOGY GRADE ETHYLENEGLYCOL-BIS(2-AMINOETHYLETHER)-N,N,N'',N''-TETRAACETICACID(EGTA) Ethylene glycol-bis(b-aminoethyl ether)-N,N,N'',N''-tetraacetic acid 3,12-Bis(carboxymethyl)-6,9-dioxa-3,12-diazatetra-decane-1,14-dioic acid (EGTA) EGTA (Ethyleneglycol bis (2-AMinoethyl ether)-N,N,N',N' Tetraacetic acid BROMOMETHANE 200UG/ML IN METHANOL EGTA, egtazic acid VENTING SCREW CAP (CLOCK) PP RED DIN 45 Ethylene Glycol Bis(β-aminoethylether)-N,N,N',N'-tetraacetic Acid 〔EGTA 2-Di(2-aminoethoxy)ethane-N,N,N,N-tetraacetic acid ETHYLENE GLYCOL-BIS(2-AMINOETHYLETHE ETHYLENE GLYCOL-BIS(B-AMINOETHYL*ETH ETHYLENE GLYCOL-O,O'-BIS(2-AMINOETHY Ethylenebis(oxyethylenenitrilo) Ethylene glycol-bis(β-aminoethyl ether)-N,N,N',N'-tetraacetic acid≥ 99% (Titration) Titriplex VI for analysis Ethylene glycol-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid, 99% EGTA EGTA bio grade 99% EGTA, egtazic acid, Glycol ether diamine tetraacetic acid 1,2-DI(2-AMINOETHOXY)ETHANE-NNN'N'-TETRA-ACETIC ACID 1,2-BIS[2-[BIS(CARBOXYMETHYL)AMINO]ETHOXY]ETHANE 2,2'-ETHYLENEDIOXYBIS[ETHYLIMINODI(ACETIC ACID)] GLYCOLETHERDIAMINE-N,N,N',N'-TETRAACETIC ACID GLYCOL ETHER DIAMINE TETRAACETIC ACID IDRANAL(R) VI GEDTA ETHYLENE-BIS(OXYETHYLENENITRILLO)TETRAACETIC ACID ETHYLENEBIS(OXYETHYLENENITRILO)TETRAACETIC ACID ETHYLENEDIOXYBIS(ETHYLAMINE)-N,N,N',N'-TETRAACETIC ACID ETHYLENEDIOXYBIS(ETHYLENENITRILO)-TETRAACETIC ACID ETHYLENE GLYCOL-BIS(2-AMINOETHYLETHER)-N,N,N',N'-TETRAACETIC ACID ETHYLENE GLYCOL BIS[2-AMINOETHYL ETHER]TETRAACETIC ACID ETHYLENE GLYCOL-BIS(2-AMINOETHYL)-N,N,N',N'-TETRAACETIC ACID