6-Bromonicotinic acid
- CAS No.
- 6311-35-9
- Chemical Name:
- 6-Bromonicotinic acid
- Synonyms
- 6-BROMOPYRIDINE-3-CARBOXYLIC ACID;6-bromonicotine acid;6-BrNA;NSC 43545;AURORA 23320;AKOS BBS-00001340;6-BROMONICOTIC ACID;IFLAB-BB F1921-0015;IFLAB-BB F1926-0006;6-Bromonicotinicaci
- CBNumber:
- CB7854044
- Molecular Formula:
- C6H4BrNO2
- Molecular Weight:
- 202.01
- MDL Number:
- MFCD01927100
- MOL File:
- 6311-35-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 200-203 °C(lit.) |
|---|---|
| Boiling point | 343.3±27.0 °C(Predicted) |
| Density | 1.813±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 3.24±0.10(Predicted) |
| form | Crystalline Powder |
| color | White |
| InChI | InChI=1S/C6H4BrNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3H,(H,9,10) |
| InChIKey | JDJBRMNTXORYEN-UHFFFAOYSA-N |
| SMILES | C1=NC(Br)=CC=C1C(O)=O |
| CAS DataBase Reference | 6311-35-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
6-Bromonicotinic acid price More Price(86)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 646989 | 6-Bromopyridine-3-carboxylic acid 96% | 6311-35-9 | 10g | $228 | 2026-04-30 | Buy |
| Sigma-Aldrich | 646989 | 6-Bromopyridine-3-carboxylic acid 96% | 6311-35-9 | 1g | $25 | 2023-06-20 | Buy |
| TCI Chemical | B2961 | 6-Bromonicotinic Acid >98.0%(GC)(T) | 6311-35-9 | 5g | $55 | 2026-04-30 | Buy |
| TCI Chemical | B2961 | 6-Bromonicotinic Acid >98.0%(GC)(T) | 6311-35-9 | 25g | $162 | 2026-04-30 | Buy |
| Usbiological | 230019 | 2-Bromo-5-pyridinecarboxylic acid | 6311-35-9 | 1g | $156 | 2026-06-03 | Buy |
6-Bromonicotinic acid Chemical Properties, Uses, Production
Chemical Properties
Off-white Plates
Uses
A potential hypolipidemic agent; a nicotinic acid analog
Synthesis
3510-66-5
6311-35-9
General procedure for the synthesis of 6-bromonicotinic acid from 2-bromo-5-methylpyridine: 2-bromo-5-methylpyridine (100 g, 0.291 mol) was dissolved in 1000 mL of water and Aliquat 336 (2 mL) was added as a phase transfer catalyst. Subsequently, potassium permanganate (251 g, 0.797 mol) was added slowly over 1 hr. The reaction mixture was stirred at 110 °C for 30 min and continued for 1 h to ensure complete reaction. Upon completion of the reaction, the mixture was filtered through diatomaceous earth while hot and the diatomaceous earth was washed with hot water. The filtrate was concentrated to half the original volume under reduced pressure. To the concentrate was added 48% hydrobromic acid (about 300 mL), and the precipitated 6-bromonicotinic acid crystals were filtered, washed with water and dried to give 52 g of white crystals in 44% yield. The product was characterized by 1H-NMR (CDCl3) with chemical shift δ (ppm) of 7.64 (1H, d, J = 8.0 Hz), 8.08 (1H, d, J = 8.0 Hz), 9.03 (1H, s).
References
[1] Synthesis, 1994, # 1, p. 87 - 92
[2] Journal of Materials Chemistry, 2005, vol. 15, # 48, p. 5164 - 5173
[3] Patent: EP1391451, 2004, A1. Location in patent: Page 143
[4] Journal of Organic Chemistry, 1949, vol. 14, p. 509,513
[5] Synthesis, 2003, # 4, p. 551 - 554
6-Bromonicotinic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Toplab Chemical Co., Ltd. | 021-31137757-00; 18121466954;18121466954 | 28328681@qq.com | China | 184 | 55 |
| Fuxin Yuke Chemical Technology Co., Ltd. | 0418-6696667 15724496333 | 2630398044@qq.com | China | 181 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Liaoning Tianhua Chemical Co., Ltd. | 0418-6530555 2855550 | China | 338 | 69 | |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| ITIC MEDCHEM(SUZHOU) CO.,LTD. | 0512-68323967 18015559028 | sales@iticmedchem.com | China | 528 | 61 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
View Latest Price from 6-Bromonicotinic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-16 | 6-Bromonicotinic acid
6311-35-9
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-09-02 | 6-Bromonicotinic acid
6311-35-9
|
$3.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-20 | 6-Bromonicotinic acid
6311-35-9
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 6-Bromonicotinic acid
6311-35-9
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 6-Bromonicotinic acid
6311-35-9
- $3.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 6-Bromonicotinic acid
6311-35-9
- $1.10
- 99.00%
- Dideu Industries Group Limited
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