2-Bromo-6-(trifluoromethyl)pyridine
- CAS No.
- 189278-27-1
- Chemical Name:
- 2-Bromo-6-(trifluoromethyl)pyridine
- Synonyms
- 2-Bromo-6-(t;2-bromo-6-trifluromethylpyridine;2-TRIFLUOROMETHYL-6-BROMOPYRIDINE;2-Bromo-6-trifluoronethylpyridine;2-Bromo-6-(Trifuoromethyl )pyridine;2-BROMO-6-(TRIFLUOROMETHYL)PYRIDINE;6-BROMO-2-(TRIFLUOROMETHYL)PYRIDINE;2-Bromo-6-(trifuluoromethyl)pyridine;Pyridine, 2-bromo-6-(trifluoromethyl)-;2-Bromo-6-(trifluoromethyl)pyridine >
- CBNumber:
- CB4496245
- Molecular Formula:
- C6H3BrF3N
- Molecular Weight:
- 225.99
- MDL Number:
- MFCD00153087
- MOL File:
- 189278-27-1.mol
- MSDS File:
- SDS
| Melting point | 48-52 °C |
|---|---|
| Boiling point | 78-79°C 14mm |
| Density | 1.707±0.06 g/cm3(Predicted) |
| Flash point | 78-79°C/14mm |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | soluble in Methanol |
| form | powder to lump |
| pka | -3.89±0.12(Predicted) |
| color | White to Orange to Green |
| InChI | InChI=1S/C6H3BrF3N/c7-5-3-1-2-4(11-5)6(8,9)10/h1-3H |
| InChIKey | DOWNSQADAFSSAR-UHFFFAOYSA-N |
| SMILES | C1(Br)=NC(C(F)(F)F)=CC=C1 |
| CAS DataBase Reference | 189278-27-1(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P301+P310+P330-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T,Xi,Xn | |||||||||
| Risk Statements | 25-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-37/39-45-36/37/39-22 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
2-Bromo-6-(trifluoromethyl)pyridine price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 661147 | 2-Bromo-6-(trifluoromethyl)pyridine 97% | 189278-27-1 | 500mg | $88 | 2023-01-07 | Buy |
| TCI Chemical | B3759 | 2-Bromo-6-(trifluoromethyl)pyridine >98.0%(GC) | 189278-27-1 | 1g | $19 | 2026-04-30 | Buy |
| TCI Chemical | B3759 | 2-Bromo-6-(trifluoromethyl)pyridine >98.0%(GC) | 189278-27-1 | 5g | $37 | 2026-04-30 | Buy |
| Apolloscientific | PC7657 | 2-Bromo-6-(trifluoromethyl)pyridine 98% | 189278-27-1 | 500mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC7657 | 2-Bromo-6-(trifluoromethyl)pyridine 98% | 189278-27-1 | 5g | $67 | 2026-06-04 | Buy |
2-Bromo-6-(trifluoromethyl)pyridine Chemical Properties, Uses, Production
Preparation
Preparation of 2-hydrazino-6-trifluoromethylpyridine: 14.5 g of 40% hydrazine hydrate and 10 ml of isopropanol were added to a 100 ml single-necked flask. 7 g of 2-chloro-6-trifluoromethylpyridine was slowly added dropwise to the mixture at room temperature. After the addition was complete, the mixture was heated to reflux and stirred for 1 h. After cooling, the reaction solution was poured into water and extracted with ethyl acetate. The organic phases were combined, dried over anhydrous sodium sulfate, and the solvent was evaporated to obtain 6.5 g of a white solid. Preparation of 2-bromo-6-trifluoromethylpyridine: 5 g of 2-hydrazino-6-trifluoromethylpyridine and 50 ml of chloroform were added to a 100 ml three-necked flask. 2.89 ml of bromine was added dropwise at room temperature. After the addition was complete, the mixture was heated to reflux and stirred for 1 h. After cooling, the reaction solution was poured into water, 10 ml of saturated sodium thiosulfate solution was added, the pH was adjusted to 8 with saturated sodium carbonate solution, and the mixture was extracted with ethyl acetate. The organic phases were combined, dried over anhydrous sodium sulfate, and the solvent was evaporated to give 5.57 g of a white solid.
Chemical Properties
White solid
Uses
2-Bromo-6-(trifluoromethyl)pyridine is a pyridine compound, which is widely used in medicine, pesticides, dyes, rubber and other fields.
2-Bromo-6-(trifluoromethyl)pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanijing m&m biotechnology Co. ,Ltd. | 025-87782433 18021532344 | 1345332203@qq.com | China | 4226 | 58 |
| Zhejiang Jiaguo Biotechnology Co., Ltd | 0576-057687838881 13968486607 | shxc7755@163.com | China | 157 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Latest Price from 2-Bromo-6-(trifluoromethyl)pyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 2-Bromo-6-(trifluoromethyl)pyridine
189278-27-1
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2019-12-20 | 2-Bromo-6-(trifluoromethyl)pyridine
189278-27-1
|
$1.00 | 100g | 98% | 200KG | Career Henan Chemical Co |
-
- 2-Bromo-6-(trifluoromethyl)pyridine
189278-27-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2-Bromo-6-(trifluoromethyl)pyridine
189278-27-1
- $1.00
- 98%
- Career Henan Chemical Co
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