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Fmoc-Phe-ol

Fmoc-Phe-ol Structure
Fmoc-Phe-ol structure
CAS No.
129397-83-7
Chemical Name:
Fmoc-Phe-ol
Synonyms
FMOC-L-PHENYLALANINOL;Fmoc-Phe-ol;Fmoc-L-Phe-OL;FMOC-PHENYLALANINOL;FMOC-PHE-OL USP/EP/BP;Fmoc-DL-Phenylalaninol;N-FMOC-L-PHENYLALANINOL;N-Fmoc-L-phenylalaninol,95%;N-Fmoc-L-phenylalaninol 98%;N-ALPHA-FMOC-L-PHENYLALANINOL
CBNumber:
CB8118024
Molecular Formula:
C24H23NO3
Molecular Weight:
373.45
MDL Number:
MFCD00235941
MOL File:
129397-83-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:55:11
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Fmoc-Phe-ol Properties

Melting point 129-130 °C
Boiling point 606.1±50.0 °C(Predicted)
Density 1.219±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 11.44±0.46(Predicted)
form Solid
Appearance White to off-white Solid
CAS DataBase Reference 129397-83-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  24/25
HazardClass  IRRITANT
HS Code  29051990

Fmoc-Phe-ol price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 276993 Fmoc-L-phenylalaninol Asreported 129397-83-7 2g $333 2026-06-03 Buy
Usbiological 276993 Fmoc-L-phenylalaninol Asreported 129397-83-7 5g $470 2026-06-03 Buy
Usbiological 276993 Fmoc-L-phenylalaninol Asreported 129397-83-7 10g $632 2026-06-03 Buy
Usbiological 276993 Fmoc-L-phenylalaninol Asreported 129397-83-7 25g $848 2026-06-03 Buy
Usbiological 238485 Fmoc-L-phenylalaninol 99+% (HPLC) ≥99%(HPLC) 1g $170 2026-06-03 Buy
Product number Packaging Price Buy
276993 2g $333 Buy
276993 5g $470 Buy
276993 10g $632 Buy
276993 25g $848 Buy
238485 1g $170 Buy

Fmoc-Phe-ol Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Synthesis

Fmoc-Phe-OH

35661-40-6

FMOC-PHE-OL

129397-83-7

The general procedure for the synthesis of Fmoc-L-phenylalaninol from Fmoc-L-phenylalanine was as follows: Fmoc-L-phenylalanine (10 mmol) was dissolved in THF (10 mL) at 0 °C, followed by the sequential addition of DIPEA (11 mmol, 1.42 mL) and EtOAc solution of 50% T3P (20 mmol, 6.36 mL). The reaction mixture was stirred at this temperature for about 10 minutes. Next, aqueous NaBH4 solution (10 mmol, 388 mg, dissolved in 0.3 mL H2O) was slowly added to the reaction system at the same temperature. The reaction progress was monitored by TLC until the reaction was complete. After completion of the reaction, the solvent was removed by rotary evaporation and the crude product was extracted with EtOAc. The organic phase was washed sequentially with 5% citric acid solution (10 mL × 2), 5% Na2CO3 solution (10 mL × 2), water and saturated saline. Finally, the organic phase was dried over anhydrous Na2SO4 and concentrated under reduced pressure to obtain the target product Fmoc-L-phenylalaninol.

References

[1] Tetrahedron Letters, 2012, vol. 53, # 38, p. 5059 - 5063
[2] Journal of Organic Chemistry, 2001, vol. 66, # 25, p. 8454 - 8462
[3] Tetrahedron Letters, 2000, vol. 41, # 32, p. 6131 - 6135
[4] Organic Letters, 2008, vol. 10, # 10, p. 1881 - 1884
[5] Tetrahedron Letters, 1999, vol. 40, # 23, p. 4395 - 4396

Fmoc-Phe-ol Preparation Products And Raw materials

Raw materials

Fmoc-Phe-OH L-Phenylglycinol 9-Fluorenylmethyl chloroformate N,N-Diisopropylethylamine Ethyl acetate
Sodium borohydride Propylphosphonic anhydride Water

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Preparation Products

Fmoc-Phe-OH

Fmoc-Phe-ol Suppliers

Global( 138)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
ChemFuture PharmaTech (Jiangsu) Ltd 5108538618 suger.wang@chemfuture.com China 832 65
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
ChemPep, Inc. +1 (888) 615-9178 / (561) 791-8787 service@chempep.com United States 2138 57
ZhengZhou HuaWen Chemical Co.Ltd 0370-2785118 17550508557 675141927@qq.com China 3201 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
ChemFuture PharmaTech (Jiangsu) Ltd 65
GL Biochem (Shanghai) Ltd 64
Capot Chemical Co., Ltd 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky (shanghai) International Co.,Ltd 60
ChemPep, Inc. 57
ZhengZhou HuaWen Chemical Co.Ltd 55

View Lastest Price from Fmoc-Phe-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FMOC-PHE-OL pictures 2020-02-01 FMOC-PHE-OL
129397-83-7
 $3.00 1KG 98% 100KG Career Henan Chemical Co
  • FMOC-PHE-OL pictures
  • FMOC-PHE-OL
    129397-83-7
  • $3.00
  • 98%
  • Career Henan Chemical Co

Fmoc-Phe-ol Spectrum

FMOC-PHE-OL(129397-83-7)1HNMR

129397-83-7(Fmoc-Phe-ol)Related Search:

FMOC-D-TRP(ME)-OH Fmoc-D-allo-Ile-OH Fmoc-D-Orn(Boc)-OH Fmoc-N-methyl-L-phenylalanine Fmoc-Tyr(tBu)-OH
Fmoc-O-benzyl-L-tyrosine FMOC-TYR(2-BR-Z)-OH FMOC-D-4-Chlorophe Fmoc-4-nitro-L-phenylalanine Nalpha-Fmoc-L-tyrosine
DL-PHENYLALANINOL L-Phenylglycinol FMOC-2-NAL-OH (S)-N-Fmoc-1-Naphthylalanine FMOC-3,5-DIIODO-L-TYROSINE
Fmoc-Tic-OH Fmoc-D-Pen(Trt)-OH Fmoc-Phe-OH

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N-FMOC-L-PHENYLALANINOL N-ALPHA-FMOC-L-PHENYLALANINOL N-(9-FLUORENYLMETHOXYCARBONYL)-L-PHENYLALANINOL FMOC-PHENYLALANINOL FMOC-(S)-2-AMINO-3-PHENYL-1-PROPANOL Fmoc-DL-Phenylalaninol NALPHA-9-Fluorenylmethoxycarbonyl-L-phenylalaninol (S)-2-(9-Fluorenylmethyloxycarbonyl)amino-3-phenyl-1-propanol, N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-phenylalaninol (S)-(9H-fluoren-9-yl)methyl 1-hydroxy-3-phenylpropan-2-ylcar (S)-(9H-fluoren-9-yl)methyl 1-hydroxy-3-phenylpropan-2-ylcarbamate (9H-fluoren-9-yl)methyl 1-hydroxy-3-phenylpropan-2-ylcarbamate REF DUPL: Fmoc-Phenylalaninol (S)-(9H-fluoren-9-yl)Methyl 1-hydroxy-3-phenylpropan-2-ylcarbaMa FMoc-PhenylalaninolFMoc-Phenylalan 9H-fluoren-9-ylmethyl N-[(2S)-1-hydroxy-3-phenylpropan-2-yl]carbamate Fmoc-L-Phe-OL Fmoc-L-phenylalaninol≥ 99% (HPLC) (S)-2-(Fmoc-amino)-3-phenyl-1-propanol Carbamic acid, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-, 9H-fluoren-9-ylmethyl ester N-Fmoc-L-phenylalaninol,95% FMOC-PHE-OL USP/EP/BP N-Fmoc-L-phenylalaninol 98% FMOC-L-PHENYLALANINOL Fmoc-Phe-ol 129397-83-7 Amino Alcohols Fmoc-Amino acid series Amino Acids peptides