3,5-Dichloro-2-cyanopyridine
- CAS No.
- 85331-33-5
- Chemical Name:
- 3,5-Dichloro-2-cyanopyridine
- Synonyms
- 3,5-dichloropicolinonitrile;3,5-Dichloropyridine-2-carbonitrile;3,5-Dichloropicolinitrile;Cyanodichloropyridine 235---;3,5-dichboro-2-cyanopyridine;3,5-DICHLORO-2-CYANOPYRIDINE;2-CYANO-3,5-DICHLOROPYRIDINE;3,5-Dichloror-2-cyanopyridine;3,5-Dichloro-2-cyanopyridine>3,5-Dichloro-pyridin-2-carbonitrile
- CBNumber:
- CB8232724
- Molecular Formula:
- C6H2Cl2N2
- Molecular Weight:
- 173
- MDL Number:
- MFCD03788758
- MOL File:
- 85331-33-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3,5-Dichloropyridine-2-carbonitrile 95% | 736074 | 1g | $30.7 |
| 3,5-Dichloropyridine-2-carbonitrile 95% | 736074 | 5g | $61.9 |
| 3,5-Dichloro-2-cyanopyridine >98.0%(GC) | D4059 | 1g | $21 |
| 3,5-Dichloro-2-cyanopyridine >98.0%(GC) | D4059 | 5g | $65 |
| 3,5-Dichloropicolinonitrile | D473985 | 500mg | $45 |
| More product size | |||
| Melting point | 101-103°C |
|---|---|
| Boiling point | 271.9±35.0 °C(Predicted) |
| Density | 1.49±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | -4.61±0.10(Predicted) |
| form | powder to crystal |
| color | White to Light yellow |
| BRN | 4390101 |
| InChI | InChI=1S/C6H2Cl2N2/c7-4-1-5(8)6(2-9)10-3-4/h1,3H |
| InChIKey | ATUOLSDAAPMVJJ-UHFFFAOYSA-N |
| SMILES | C1(C#N)=NC=C(Cl)C=C1Cl |
| CAS DataBase Reference | 85331-33-5(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-36-36/37 | |||||||||
| RIDADR | 3439 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2933399990 | |||||||||
| Storage Class | 6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
3,5-Dichloro-2-cyanopyridine price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 736074 | 3,5-Dichloropyridine-2-carbonitrile 95% | 85331-33-5 | 1g | $30.7 | 2023-01-07 | Buy |
| Sigma-Aldrich | 736074 | 3,5-Dichloropyridine-2-carbonitrile 95% | 85331-33-5 | 5g | $61.9 | 2023-01-07 | Buy |
| TCI Chemical | D4059 | 3,5-Dichloro-2-cyanopyridine >98.0%(GC) | 85331-33-5 | 1g | $21 | 2026-03-19 | Buy |
| TCI Chemical | D4059 | 3,5-Dichloro-2-cyanopyridine >98.0%(GC) | 85331-33-5 | 5g | $65 | 2026-03-19 | Buy |
| TRC | D473985 | 3,5-Dichloropicolinonitrile | 85331-33-5 | 500mg | $45 | 2021-12-16 | Buy |
3,5-Dichloro-2-cyanopyridine Chemical Properties,Uses,Production
Chemical Properties
Yellow to light brown crystalline powder
Uses
3,5-Dichloro-2-cyanopyridine is an intermediate in the industrial synthesis of nicotinic acid and nicotinamide.
Synthesis
15177-57-8
7677-24-9
85331-33-5
General procedure for the synthesis of 2-cyano-3,5-dichloropyridine from 3,5-dichloropyridine 1-oxide and trimethylcyanosilane: 21.8 mL (0.174 mol) of trimethylcyanosilane and 14.6 mL (0.158 mol) of dimethylcarbamoyl chloride were sequentially added to 26 g (0.158 mol) of 3,5-dichloropyridine 1-oxide in an 80-mL dichloromethane solution. The reaction mixture was stirred at room temperature for 48 hours. After the reaction was completed, 100 mL of 10% aqueous NaHCO3 solution was added and stirred vigorously for 10 minutes. After separating the organic and aqueous phases, the aqueous phase was extracted once with dichloromethane. All organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography using dichloromethane as eluent. The target fraction was collected, concentrated and recrystallized from a small amount of methanol to give 11 g (40.2% yield) of 2-cyano-3,5-dichloropyridine with a melting point of 102 °C. The target fraction was collected, concentrated and recrystallized from a small amount of methanol.
References
[1] Patent: US2003/232842, 2003, A1. Location in patent: Page 8
3,5-Dichloro-2-cyanopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd. | +86-18616643091 | info@rochipharma.com | China | 246 | 58 |
| Cangzhou Kangrui Pharma Tech Co. Ltd., | +86-18632776803 +86-13833998158 | cangzhoukangrui@126.com | China | 773 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21591 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29820 | 58 |
View Lastest Price from 3,5-Dichloro-2-cyanopyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-29 | 3,5-Dichloro-2-cyanopyridine
85331-33-5
|
US $0.00 / KG | 1KG | 99% | 100mt | Jinan Finer Chemical Co., Ltd | |
 |
2025-12-01 | 3,5-Dichloro-2-cyanopyridine
85331-33-5
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-09-25 | 3,5-Dichloro-2-cyanopyridine
85331-33-5
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- 3,5-Dichloro-2-cyanopyridine
85331-33-5
- US $0.00 / KG
- 99%
- Jinan Finer Chemical Co., Ltd
-
- 3,5-Dichloro-2-cyanopyridine
85331-33-5
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 3,5-Dichloro-2-cyanopyridine
85331-33-5
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
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