5-Chloro-3-phenylanthranil
- CAS No.
- 719-64-2
- Chemical Name:
- 5-Chloro-3-phenylanthranil
- Synonyms
- 5-CHLORO-3-PHENYLBENZO[C]ISOXAZOLE;NSC 405896;TIMTEC-BB SBB007675;Oxaliplatin Impurity 8;3-PHENYL-5-CHLOROANTHRANIL;5-Chloro-3-phenylanthranil;5-Chloro-3-phenylbenzisoxazole;3-Phenyl-5-chlorobenzisoxazole;5-Chloro-3-Phenylbenzoisoxazole;3-PHENYL-5-CHLORO-BENZOISOXAZOLE
- CBNumber:
- CB8265704
- Molecular Formula:
- C13H8ClNO
- Molecular Weight:
- 229.66
- MDL Number:
- MFCD00014573
- MOL File:
- 719-64-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 115-117 °C(lit.) |
|---|---|
| Boiling point | 395.4±22.0 °C(Predicted) |
| Density | 1.298 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | -4.98±0.30(Predicted) |
| form | Crystalline Powder |
| color | Yellow |
| InChI | InChI=1S/C13H8ClNO/c14-10-6-7-12-11(8-10)13(16-15-12)9-4-2-1-3-5-9/h1-8H |
| InChIKey | MUHJZJKVEQASGY-UHFFFAOYSA-N |
| SMILES | N1=C2C(C=C(Cl)C=C2)=C(C2=CC=CC=C2)O1 |
| CAS DataBase Reference | 719-64-2(CAS DataBase Reference) |
| FDA UNII | 8PE4QT3TQK |
| EPA Substance Registry System | 2,1-Benzisoxazole, 5-chloro-3-phenyl- (719-64-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H413-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-37/38-36 | |||||||||
| Safety Statements | 26-36/37/39-37 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2934.99.4400 | |||||||||
| NFPA 704 |
|
5-Chloro-3-phenylanthranil price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S359629 | 5-CHLORO-3-PHENYLANTHRANIL AldrichCPR | 719-64-2 | 50MG | $121 | 2026-04-30 | Buy |
| TCI Chemical | C1687 | 5-Chloro-3-phenyl-2,1-benzisoxazole >96.0%(GC) | 719-64-2 | 25g | $111 | 2026-04-30 | Buy |
| TRC | TRC-C377555-5G | 5-Chloro-3-phenyl-2,1-benzisoxazole | 719-64-2 | 5g | $91 | 2026-06-03 | Buy |
| TRC | TRC-C377555-50G | 5-Chloro-3-phenyl-2,1-benzisoxazole | 719-64-2 | 50g | $378 | 2026-06-03 | Buy |
| TRC | TRC-C377555-25G | 5-Chloro-3-phenyl-2,1-benzisoxazole | 719-64-2 | 25g | $205 | 2026-06-03 | Buy |
5-Chloro-3-phenylanthranil Chemical Properties,Uses,Production
Chemical Properties
Crystallized (ethanol). Melting point 115-117°C.
Uses
5-Chloro-3-phenyl-2,1-benzisoxazole, is a Heterocyclic Building Block used for the synthesis of pharmaceuticals and other organic compounds. It is used in the synthesis of novel 2H-1, 4-benzodiazepine-2-ones as inhibitors of HIV-1 transcription.It can also be sued for the synthesis of Nitroacridinones derivatives.
Synthesis
719-59-5
719-64-2
General procedure for the synthesis of 5-chloro-3-phenylbenzo[c]isoxazoles from 2-amino-5-chlorobenzophenone: Oxone (0.270 g, 0.44 mmol) was added to (E)-1-(2-aminophenyl)-3-(4-fluorophenyl)prop-2-en-1-one (1 g, 0.44 mmol) in a MeCN/HO (2.5 mL/2.5 mL) solution. The reaction mixture was stirred at room temperature and the reaction progress was monitored by TLC and GC-MS. After stirring for 24 h, HO (150 mL) and CHCl (150 mL) were added for extraction. The organic layer was separated and the aqueous layer was further extracted with CHCl The combined organic layers were washed with HO, dried over anhydrous NaSO, filtered and concentrated. Purification by silica gel column chromatography (n-hexane/EtOAc, 98:2) afforded 3 g of the target product 2,1-benzisoxazole.
References
[1] Synthesis (Germany), 2016, vol. 48, # 18, p. 3017 - 3030
[2] Helvetica Chimica Acta, 1979, vol. 62, p. 185 - 197
5-Chloro-3-phenylanthranil Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6746 | 52 |
| Jinan Trio PharmaTech Co., Ltd. | 0531-88811783 | sales@trio-pharmatech.com | China | 1856 | 62 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
View Lastest Price from 5-Chloro-3-phenylanthranil manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | 5-Chloro-3-phenylbenzo-2,1-isoxazole
719-64-2
|
25kg/Drum | 98.0% | 1000KG | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2021-10-30 | 5-Chloro-3-phenylbenzisoxazole
719-64-2
|
$10.00 | 1Kg/Bag | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd | |
 |
2020-01-13 | 5-CHLORO-3-PHENYLANTHRANIL
719-64-2
|
$1.00 | 1KG | 85.0-99.8% | 200kgs | Career Henan Chemical Co |
-
- 5-Chloro-3-phenylbenzo-2,1-isoxazole
719-64-2
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 5-Chloro-3-phenylbenzisoxazole
719-64-2
- $10.00
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
-
- 5-CHLORO-3-PHENYLANTHRANIL
719-64-2
- $1.00
- 85.0-99.8%
- Career Henan Chemical Co
