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SB 269970 hydrochloride

SB 269970 hydrochloride Structure
SB 269970 hydrochloride structure
CAS No.
201038-74-6
Chemical Name:
SB 269970 hydrochloride
Synonyms
CS-776;SB269970HCl;SB-269970;SB 269970;SB 269970 hydrochlor;SB269970 (SB-269970A);SB 269970 hydrochloride;(R)-3-((2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)phenol;Phenol, 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]-;(R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine;Pyrrolidine, 1-((3-hydroxyphenyl)sulfonyl)-2-(2-(4-methyl-1-piperidinyl)ethyl)-, (R)-
CBNumber:
CB3490266
Molecular Formula:
C18H28N2O3S
Molecular Weight:
352.49
MDL Number:
MFCD08056273
MOL File:
201038-74-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:05
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SB 269970 hydrochloride Properties

Boiling point 512.9±56.0 °C(Predicted)
Density 1.188
storage temp. Inert atmosphere,2-8°C
solubility H2O: 22 mg/mL
form solid
pka 8.88±0.10(Predicted)
color White to off-white
FDA UNII KC8KP5XU6F

SAFETY

Risk and Safety Statements

WGK Germany  3

SB 269970 hydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 465905 SB 269970 201038-74-6 10mg $453 2026-06-03 Buy
Usbiological 465905 SB 269970 201038-74-6 25mg $729 2026-06-03 Buy
ChemScene CS-1645 SB-269970 98.78% 201038-74-6 5mg $121 2026-06-04 Buy
ChemScene CS-1645 SB-269970 98.78% 201038-74-6 10mg $188 2026-06-04 Buy
ChemScene CS-1645 SB-269970 98.78% 201038-74-6 25mg $402 2026-06-04 Buy
Product number Packaging Price Buy
465905 10mg $453 Buy
465905 25mg $729 Buy
CS-1645 5mg $121 Buy
CS-1645 10mg $188 Buy
CS-1645 25mg $402 Buy

SB 269970 hydrochloride Chemical Properties, Uses, Production

Uses

SB 269970 is a selective and potent SR-7 antagonist.

Definition

ChEBI: 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]phenol is a sulfonamide.

Biological Activity

Potent and selective 5-HT 7 receptor antagonist (pK i values are 8.9, 7.2 and 6.0 for 5-HT 7A , 5-HT 5A and 5-HT 1B and < 6.0 for 5-HT 1A , 5-HT 1D , 5-HT 1E , 5-HT 1F , 5-HT 2A , 5-HT 2B , 5-HT 2C , 5-HT 4 and 5-HT 6 receptors respectively). Brain penetrant in vivo .

in vivo

SB-269970 (3-30 mg/kg; i.p.; once) significantly blocks amphetamine and ketamine-induced hyperactivity[2].

Animal Model:Male C57BL6/J mice[2]
Dosage:3, 10, 30 mg/kg
Administration:Intraperitoneal injection; once
Result:Significantly blocked amphetamine and ketamine-induced hyperactivity.

IC 50

Human 5-HT7 Receptor: 8.3 (pKi)

SB 269970 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

SB 269970 hydrochloride Suppliers

Global Suppliers ( 84)
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Chengdu NoVi Biotechnology Co., Ltd. 028-81458053 novibiotech@163.com sales@novi-biotech.com China 226 55
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2774 58
AdooQ Bioscience CHINA 025-58849295 info@adooq.cn China 2981 60
SPIRO PHARMA eric_feng1954@126.com China 9239 55
BePharm Ltd 400-685-9117 market@bepharm.com China 15081 60
Chengdu Huachun Technology Co., Ltd 400-1166-196 15982826727 cdhxsj@163.com China 14571 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9729 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chengdu NoVi Biotechnology Co., Ltd. 55
AdooQ BioScience, LLC 58
AdooQ Bioscience CHINA 60
SPIRO PHARMA 55
BePharm Ltd 60
Chengdu Huachun Technology Co., Ltd 60
ShangHai Biochempartner Co.,Ltd 62
Shanghai Chaolan Chemical Technology Center 58
Amadis Chemical Company Limited 58

View Latest Price from SB 269970 hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SB-269970 pictures 2026-05-22 SB-269970
201038-74-6
 $2370.00-3500.00 10g TargetMol Chemicals Inc.
SB-269970 pictures 2026-05-21 SB-269970
201038-74-6
 $2370.00-3500.00 10g TargetMol Chemicals Inc.
SB-269970 pictures 2025-08-22 SB-269970
201038-74-6
 $2420.00-4600.00 10g TargetMol Chemicals Inc.
  • SB-269970 pictures
  • SB-269970
    201038-74-6
  • $2370.00-3500.00
  • TargetMol Chemicals Inc.
  • SB-269970 pictures
  • SB-269970
    201038-74-6
  • $2370.00-3500.00
  • TargetMol Chemicals Inc.
  • SB-269970 pictures
  • SB-269970
    201038-74-6
  • $2420.00-4600.00
  • TargetMol Chemicals Inc.

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CS-776 SB-269970;SB 269970 SB269970HCl (2R)-1-[(3-HYDROXYPHENYL)SULFONYL]-2-[2-(4-METHYL-1-PIPERIDINYL)ETHYL]PYRROLIDINE HYDROCHLORIDE Pyrrolidine, 1-((3-hydroxyphenyl)sulfonyl)-2-(2-(4-methyl-1-piperidinyl)ethyl)-, (R)- (R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine (R)-3-((2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)phenol Phenol, 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]- SB 269970 hydrochlor SB269970 (SB-269970A) SB 269970 hydrochloride 201038-74-6 Serotonin receptor