ChemicalBook >> CAS DataBase List >>HL 725
HL 725
- CAS No.
- 78416-81-6
- Chemical Name:
- HL 725
- Synonyms
- TREQUINSIN;HL 725;HL 725 HCL;Trequinsin, HCl;TREQUINSIN HYDROCHLORIDE;Riluzole Impurity 13-13C;DTCZZBVPTHVXFA-OSMRDGEFSA-N;TREQUINSIN HYDROCHLORIDE MINIMUM 98%;4,6-trimethylphenyl)imino)--2-((monohydrochloride;Trequinsin, Hydrochloride - CAS 78416-81-6 - Calbiochem
- CBNumber:
- CB9238844
- Molecular Formula:
- C24H28ClN3O3
- Molecular Weight:
- 441.95
- MDL Number:
- MFCD01076563
- MOL File:
- 78416-81-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-11 16:31:51
| Product description | Number | Pack Size | Price |
| Trequinsin hydrochloride ≥98% | T2057 | 10mg | $383 |
| Trequinsin, Hydrochloride | 382425 | 10mg | $366 |
| Trequinsin (hydrochloride) ≥98% | 17217 | 1mg | $49 |
| Trequinsin (hydrochloride) ≥98% | 17217 | 5mg | $213 |
| Trequinsin (hydrochloride) ≥98% | 17217 | 10mg | $306 |
| Melting point | 210-211 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7)) |
|---|---|
| storage temp. | Desiccate at RT |
| solubility | DMSO: 100 mM; Ethanol: 100 mM |
| form | Pale yellow solid |
| color | Light yellow to yellow |
| Water Solubility | water: 500μM |
| InChI | 1S/C24H27N3O3.ClH/c1-14-9-15(2)23(16(3)10-14)25-22-13-19-18-12-21(30-6)20(29-5)11-17(18)7-8-27(19)24(28)26(22)4;/h9-13H,7-8H2,1-6H3;1H/b25-22+; |
| InChIKey | DTCZZBVPTHVXFA-OSMRDGEFSA-N |
| SMILES | Cl[H].COc1cc2CCN3C(=O)N(C)C(\C=C3c2cc1OC)=N\c4c(C)cc(C)cc4C |
| FDA UNII | 739I2958C1 |
| UNSPSC Code | 41106305 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| RTECS | UW7727000 |
| Storage Class | 11 - Combustible Solids |
HL 725 price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T2057 | Trequinsin hydrochloride ≥98% | 78416-81-6 | 10mg | $383 | 2026-04-30 | Buy |
| Sigma-Aldrich | 382425 | Trequinsin, Hydrochloride | 78416-81-6 | 10mg | $366 | 2026-04-30 | Buy |
| Cayman Chemical | 17217 | Trequinsin (hydrochloride) ≥98% | 78416-81-6 | 1mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 17217 | Trequinsin (hydrochloride) ≥98% | 78416-81-6 | 5mg | $213 | 2026-04-30 | Buy |
| Cayman Chemical | 17217 | Trequinsin (hydrochloride) ≥98% | 78416-81-6 | 10mg | $306 | 2026-04-30 | Buy |
HL 725 Chemical Properties,Uses,Production
Uses
PDE inhibitor
Uses
Trequinsin Hydrochloride is an ultrapotent inhibitor of phosphodiesterase (PDE) 3.
Biological Activity
Extremely potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3; IC 50 = 250 pM). Potently inhibits arachidonic acid-induced aggregation of human platelets (IC 50 = 50 pM). Orally active antihypertensive agent; reduces systemic blood pressure in both normotensive and hypertensive animal models.
storage
Desiccate at RT
HL 725 Preparation Products And Raw materials
Raw materials
Preparation Products
HL 725 Suppliers
Global( 53)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39039 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +8613382787392 | sales@aeechem.com | China | 10001 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8065 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2994 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
View Lastest Price from HL 725 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Trequinsin hydrochloride
78416-81-6
|
$82.00-818.00 | 99.91% | 10g | TargetMol Chemicals Inc. |
-
- Trequinsin hydrochloride
78416-81-6
- $82.00-818.00
- 99.91%
- TargetMol Chemicals Inc.
78416-81-6(HL 725)Related Search:
4,6-trimethylphenyl)imino)--2-((monohydrochloride
4h-pyrimido(6,1-a)isoquinolin-4-one,2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl
HL 725
HL 725 HCL
Trequinsin, Hydrochloride - CAS 78416-81-6 - Calbiochem
2,3,6,7-TETRAHYDRO-9,10-DIMETHOXY-3-METHYL-2-[(2,4,6-TRIMETHYLPHENYL)IMINO]-4H-PYRIMIDO[6,1-A]ISOQUINOLIN-4-ONE HYDROCHLORIDE
9,10-DIMETHOXY-2-MESITYLIMINO-3-METHYL-2,3,6,7-TETRAHYDRO-4H-PYRIMIDO-(6,1-A)-ISOQUINOLIN-4-ONE, HCL
9,10-DIMETHOXY-2-MESITYLIMINO-3-METHYL-2,3,6,7-TETRAHYDRO-4H-PYRIMIDO-[6,1A]-ISOQUINOLIN-4-ONE HYDROCHLORIDE
TREQUINSIN HYDROCHLORIDE MINIMUM 98%
TREQUINSIN HYDROCHLORIDE
Trequinsin, HCl
4H-Pyrimido(6,1-A)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride
2,3,6,7-Tetrahydro-9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-4H-pyrimido[6,1-a]isoquinolin-4-onehydrochloride
DTCZZBVPTHVXFA-OSMRDGEFSA-N
Riluzole Impurity 13-13C
TREQUINSIN
78416-81-6
C24H27N3O3HCl
C24H27N3O3
Cyclic Nucleotide Metabolism
G Proteins and Cyclic Nucleotides
Phosphodiesterase Inhibitors
BioChemical
Cell Signaling and Neuroscience
Cell Biology
