4-Amino-5-aminomethyl-2-methylpyrimidine
- CAS No.
- 95-02-3
- Chemical Name:
- 4-Amino-5-aminomethyl-2-methylpyrimidine
- Synonyms
- Grewe DiaMine;4-amino-2-methylpyrimidine-5-methylamine;2-methyl-4-amino-5-aminomethylpyrimidine;Thiamine Impurity 16;Thiamine Impurity 48;Thiamine Impurity 34;Vitamin B1 Impurity 9;Diazinon Impurity 6 (Diazoxon);Thiamine /Vitamin B1 Impurity 19;2-Methyl-4-aminopyrimidine-5-methanamine
- CBNumber:
- CB9757404
- Molecular Formula:
- C6H10N4
- Molecular Weight:
- 138.17
- MDL Number:
- MFCD00058194
- MOL File:
- 95-02-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Amino-5-aminomethyl-2-methylpyrimidine | A2633 | 200MG | $213 |
| 4-Amino-5-aminomethyl-2-methylpyrimidine | TRC-A581865-500MG | 500mg | $376 |
| 4-Amino-5-aminomethyl-2-methylpyrimidine | TRC-A581865-250MG | 250mg | $210 |
| 4-Amino-5-aminomethyl-2-methylpyrimidine | TRC-A581865-1G | 1g | $648 |
| 4-Amino-5-aminomethyl-2-methylpyrimidine | FA17606 | 0.5g | $362.81 |
| Melting point | 270-272°C |
|---|---|
| Boiling point | 121-125 °C |
| Density | 1.207 |
| vapor pressure | 0.012-0.019Pa at 20-25℃ |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly) |
| form | Solid |
| pka | 7.70±0.29(Predicted) |
| color | Off-White to Beige |
| PH | 10.65 at 20℃ and 10g/L |
| InChI | InChI=1S/C6H10N4/c1-4-9-3-5(2-7)6(8)10-4/h3H,2,7H2,1H3,(H2,8,9,10) |
| InChIKey | OZOHTVFCSKFMLL-UHFFFAOYSA-N |
| SMILES | C1(C)=NC=C(CN)C(N)=N1 |
| LogP | -2.27 at 20℃ and pH7 |
| Surface tension | 72.77mN/m at 1g/L and 20℃ |
| FDA UNII | EU1UNR0P28 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| HS Code | 2933599590 |
| REACH Registrations | Active |
4-Amino-5-aminomethyl-2-methylpyrimidine price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A2633 | 4-Amino-5-aminomethyl-2-methylpyrimidine | 95-02-3 | 200MG | $213 | 2026-04-30 | Buy |
| TRC | TRC-A581865-500MG | 4-Amino-5-aminomethyl-2-methylpyrimidine | 95-02-3 | 500mg | $376 | 2026-06-03 | Buy |
| TRC | TRC-A581865-250MG | 4-Amino-5-aminomethyl-2-methylpyrimidine | 95-02-3 | 250mg | $210 | 2026-06-03 | Buy |
| TRC | TRC-A581865-1G | 4-Amino-5-aminomethyl-2-methylpyrimidine | 95-02-3 | 1g | $648 | 2026-06-03 | Buy |
| Biosynth | FA17606 | 4-Amino-5-aminomethyl-2-methylpyrimidine | 95-02-3 | 0.5g | $362.81 | 2026-06-04 | Buy |
4-Amino-5-aminomethyl-2-methylpyrimidine Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Substrate for TenA enzyme in the thiamin salvage pathway
Definition
ChEBI: An aminopyrimidine compound having its amino substituent at the 4-position together with methyl and aminomethyl substituents at the 2- and 5-positions respectively.
Synthesis
In an autoclave, the mixture of 4-Amino-5-aminomethyl-2-methylpyrimidine (2.0 kg, 15 mol), modified Raney nickel (wet weight 300 g), and saturated methanol solution of ammonia (20 L) was heated to 100 ℃ and stirred for 5 h at this temperature under 4 MPa hydrogen pressure. Then, the mixture was cooled to room temperature and filtered; 4-Amino-5-aminomethyl-2-methyl pyrimidine was obtained as a white solid (2.0 kg, 98%) by concentrating the filtrate[1].
References
[1] Lei Zhao, Fen-Er Chen, Xiao-Dong Ma. “Development of Two Scalable Syntheses of 4-Amino-5-aminomethyl-2-methylpyrimidine: Key Intermediate for Vitamin B1.” Organic Process Research & Development 16 1 (2011): 57–60.
4-Amino-5-aminomethyl-2-methylpyrimidine Preparation Products And Raw materials
4-Amino-5-aminomethyl-2-methylpyrimidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou uniringchem Co., Ltd. | 13585446801 | sales@uniringchem.com | China | 69 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-17392712779 | 1097@dideu.com | China | 3989 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14032 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21531 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3004 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; 19817745290 | bd@blocksynth.com | China | 5971 | 58 |
View Lastest Price from 4-Amino-5-aminomethyl-2-methylpyrimidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | 4-Amino-5-aminomethyl-2-methylpyrimidine
95-02-3
|
1KG | 99.0% | 1000KG | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2025-11-18 | 4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE, DIHYDROCHLORIDE
95-02-3
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 4-Amino-5-aminomethyl-2-methylpyrimidine
95-02-3
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE, DIHYDROCHLORIDE
95-02-3
- $1.10
- 99.00%
- Dideu Industries Group Limited
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