| Company Name: |
Cool Pharm, Ltd |
| Tel: |
021-60455363 18019463053 |
| Email: |
sales@coolpharm.com |
- Biotin-PEG7-amine
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2025-06-07
- CAS:1334172-76-7
- Min. Order: 1000mg
- Purity: >95.00%
- Supply Ability: 1000mg
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| | Biotin-PEG7-Amine Basic information |
| Product Name: | Biotin-PEG7-Amine | | Synonyms: | Biotin-PEG7-Amine;Biotin-PEG7-NH2;Biotin-dPEG(R)7-NH2;N-(23-amino-3,6,9,12,15,18,21-heptaoxatricosyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide;Biotin-PEG8-amine;Biotin-PEG7-CH2CH2NH2;alpha-Biotin-omega-amino hepta(ethylene glycol);1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(23-amino-3,6,9,12,15,18,21-heptaoxatricos-1-yl)hexahydro-2-oxo-, (3aS,4S,6aR)- | | CAS: | 1334172-76-7 | | MF: | C26H50N4O9S | | MW: | 594.76 | | EINECS: | | | Product Categories: | peg;SiChem | | Mol File: | 1334172-76-7.mol |  |
| | Biotin-PEG7-Amine Chemical Properties |
| Boiling point | 785.9±60.0 °C(Predicted) | | density | 1.151±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in Water, DMSO, DCM, DMF | | form | solid or viscous liquid | | pka | 13.90±0.40(Predicted) | | color | White to off-white | | InChIKey | HRGIYGOBSBFLMX-UHFFFAOYSA-N | | SMILES | NCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | Biotin-PEG7-Amine Usage And Synthesis |
| Description | Biotin-PEG7-amine is a biotin PEG reagent that is reactive with NHS ester or with carboxutlic acid in the presence of EDC or HATU activator. | | Uses | Biotin-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | reaction suitability | reaction type: Biotinylations
reagent type: cross-linking reagent | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Biotin-PEG7-Amine Preparation Products And Raw materials |
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